Results 181 to 190 of about 81,348 (224)
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A review on analytical methods for natural berberine alkaloids
Journal of Separation Science, 2019AbstractBerberine alkaloids, a group of protoberberine alkaloids under the classification of isoquinoline alkaloids, include berberine, coptisine, palmatine, columbamine, dehydrocorydaline, jatrorrhizine, and epiberberine from natural sources. Studies have shown that berberine alkaloids have various pharmacological functions, such as antibacterial ...
Bing Wang
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Inhibitory Effects of Berberine-Type Alkaloids on Elastase
Planta Medica, 1993Berberine-type alkaloids and some structurally related alkaloids were tested for inhibitory activity on porcine pancreatic elastase (PPE) and human sputum elastase (HSE). The chlorides of berberine, coptisine, and sanguinarine significantly inhibited the elastolytic activity of both the enzymes, but tetrahydroberberine had no effect on the activity. It
Masao Hirotani, Tsutomu Furuya
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Biomolecules, 2022 Tuberculosis (TB) is a widespread infectious disease caused by Mycobacterium tuberculosis. The increasing incidence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has created a need for new antiTB agents with new chemical ...
Klara Konecna +2 more
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Berberine: An Antihypoglycemic Alkaloid
Journal of Functional And Environmental Botany, 2013The term diabetes mellitus describes a metabolic disorder of multiple aetiology characterised by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. The effects of diabetes mellitus include long-term damage, dysfunction and failure of various organs ...
Abhimanyu Sharma, Amla Batra
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Effect of alkaloid berberine on the susceptibility of nontuberculous mycobacteria to antibiotics
Polish Journal of Veterinary Sciences, 2022Nontuberculous mycobacteria (NTM) have recently emerged as important bacterial pathogens of both animals and humans. In this study, we aimed to evaluate the effect of a combination of ten antibiotics with an inhibitor of efflux pumps (EPI), i.e. berberine (BER), against 6 strains of NTM.
K, Puk, L, Guz
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Berberine: A naturally occurring phototoxic alkaloid
Journal of Chemical Ecology, 1984The isoquinoline alkaloid berberine, present in nine different plant families was found to be phototoxic to mosquito larvae. In the presence of near UV the LC50 for acute 24-hr toxicity was 8.8 ppm compared to 250 ppm for dark controls. Mosquito larvae that were treated with 10 ppm berberine plus near UV for 24 hr and then transferred to berberine-free
B J, Philogène +6 more
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Anticonvulsant activity of berberine, an isoquinoline alkaloid in mice
Epilepsy & Behavior, 2010Berberine, an isoquinoline alkaloid is reported to modulate several neurotransmitter systems like N-methyl-D-aspartate, nitric oxide and serotonin, which modulate convulsions. In addition, it is suggested that Berberis vulgaris may be useful in treatment of convulsion and epilepsy.
Pravinkumar, Bhutada +5 more
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Alkaloids as Aldose Reductase Inhibitors, with Special Reference to Berberine
The Journal of Alternative and Complementary Medicine, 2014Aldose reductase is the rate-limiting enzyme of the polyol pathway that leads to conversion of glucose to sorbitol. Its increased activity, which results in abnormal activation of the polyol pathway, is implicated in the development of long-term complications of diabetes mellitus. Different plant species and their active components have shown potent in
Sakshi, Gupta +2 more
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Genotoxicity of the isoquinoline alkaloid berberine in prokaryotic and eukaryotic organisms
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1993Berberine, a medically important isoquinoline alkaloid, was tested for the presence of genotoxic, mutagenic and recombinogenic activities in microorganisms. This alkaloid did not show genotoxic activity with or without metabolic activation in the SOS chromotest.
M S, Pasqual +3 more
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The mechanisms of ROS-photogeneration by berberine, a natural isoquinoline alkaloid
Journal of Photochemistry and Photobiology B: Biology, 2010The reactive oxygen species (ROS)-photogenerating mechanisms of berberine (BER) have been elucidated based on the time-dependent density functional theory calculated triplet excited (T(1)) state characters in explicit solvent models. The lowest triplet excitation energy of BER is obtained for the first time.
Liang, Shen, Hong-Fang, Ji
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