Berberine: A nematocidal alkaloid from Argemone mexicana against Strongyloides venezuelensis
Experimental Parasitology, 2021Strongyloidiasis is a parasitosis that represents a public health problem, in tropical regions. The present study aimed to investigate the anthelmintic effects of several extracts of Argemone mexicana, as well as its main component berberine (Ber) against the third-stage larvae (L3) of Strongyloides venezuelensis in-vitro experiments.
Joel H, Elizondo-Luévano +7 more
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Fungicidal and Herbicidal Activities of Berberine Related Alkaloids
Bioscience, Biotechnology, and Biochemistry, 2000The 23 quaternary and tertiary protoberberines related to berberine were tested for in vitro and/or in vivo fungicidal and herbicidal activities. Among the compounds tested, there was some activity observed with some of only the protoberberinium salts, but not sufficiently strong or broad spectrum for agrochemical use. From the structure-activity point
K, Iwasa, M, Moriyasu, B, Nader
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Anticonvulsant activity of berberine, an isoquinoline alkaloid in mice
Epilepsy & Behavior, 2010Berberine, an isoquinoline alkaloid is reported to modulate several neurotransmitter systems like N-methyl-D-aspartate, nitric oxide and serotonin, which modulate convulsions. In addition, it is suggested that Berberis vulgaris may be useful in treatment of convulsion and epilepsy.
Pravinkumar, Bhutada +5 more
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Antinociceptive effect and identification of berberine alkaloid in Berberis ruscifolia extracts
Journal of Ethnopharmacology, 2023Aerial parts (leaves and stems) of Berberis ruscifolia Lam. are a usual preparation as an analgesic, anti-inflammatory, antimalarial, antibacterial, and digestive in folk medicine. However, there were no previous studies of its chemical composition and biological activity related to analgesic effects.The evaluation of the anti-nociception of the ...
Micaela Paula Del Gaudio +4 more
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Alkaloids as Aldose Reductase Inhibitors, with Special Reference to Berberine
The Journal of Alternative and Complementary Medicine, 2014Aldose reductase is the rate-limiting enzyme of the polyol pathway that leads to conversion of glucose to sorbitol. Its increased activity, which results in abnormal activation of the polyol pathway, is implicated in the development of long-term complications of diabetes mellitus. Different plant species and their active components have shown potent in
Sakshi, Gupta +2 more
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Abstract Photochemical and selective synthesis of 1-benzyl-1,2-dihydroisoquinolines was achieved from isoquinolines, methyl chloroformate and electron-rich benzyltrifluoro-borates in the presence of pyridine that inhibited subsequent formation of possible cyclized pavine type products.
Takumi Makiura, Yutaka Nishigaichi
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Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry
Journal of Biochemical and Biophysical Methods, 2008The growth thermogenic curves of Escherichia coli (E. coli) affected by berberine, coptisine and palmatine were determined quantitatively by microcalorimetry. The power-time curves of E. coli with and without the three berberines alkaloids (BA) were acquired, meanwhile the extent and duration of inhibitory effects on the metabolism were evaluated by ...
Dan, Yan +3 more
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Genotoxicity of the isoquinoline alkaloid berberine in prokaryotic and eukaryotic organisms
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1993Berberine, a medically important isoquinoline alkaloid, was tested for the presence of genotoxic, mutagenic and recombinogenic activities in microorganisms. This alkaloid did not show genotoxic activity with or without metabolic activation in the SOS chromotest.
M S, Pasqual +3 more
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The mechanisms of ROS-photogeneration by berberine, a natural isoquinoline alkaloid
Journal of Photochemistry and Photobiology B: Biology, 2010The reactive oxygen species (ROS)-photogenerating mechanisms of berberine (BER) have been elucidated based on the time-dependent density functional theory calculated triplet excited (T(1)) state characters in explicit solvent models. The lowest triplet excitation energy of BER is obtained for the first time.
Liang, Shen, Hong-Fang, Ji
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Berberine Alkaloid as a Sensitive Fluorescent Probe for Bile Salt Aggregates
The Journal of Physical Chemistry B, 2007Effect of sodium cholate (NaC) bile salt on the absorption and fluorescence properties of berberine cation was studied in aqueous solution and water-cosolvent mixtures. The alteration of the fluorescent behavior with increasing NaC concentration showed an entirely different trend from that found previously in the presence of sodium dodecylsulfate ...
Megyesi, Mónika, Biczók, László
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