Results 51 to 60 of about 762,060 (221)

INFLUENCE OF PLEUROTUS OSTREATUS β-GLUCANS ON THE GROWTH AND ACTIVITY OF CERTAIN LACTIC ACID BACTERIA

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2018
Over the last few decades, polysaccharides of fungi, namely beta-glucans captivated researchers' attention for they hold many significant properties; the most important ones are immunomodulating and antitumor properties. Although, beta-glucans are widely
M. S. KOKINA   +6 more
doaj  

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

open access: yesAdvanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou   +11 more
wiley   +1 more source

The importance of beta-glucans in human nutrition.

open access: yes, 2009
V bakalářské práci je zpracována problematika vlákniny a její konkrétní složky -beta-glukanů. Pojednáno je o charakteristice, zdrojích a fyziologických účincích jak beta-glukanů tak i vlákniny.
Janírková, Gabriela
core   +2 more sources

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Oral beta-glucan adjuvant therapy converts nonprotective Th2 response to protective Th1 cell-mediated immune response in mammary tumor-bearing mice.

open access: yesFolia Histochemica et Cytobiologica, 2007
Beta (1-3)-D-glucans were identified almost 40 years ago as biological response modifiers that stimulated tumor rejection. In vitro studies have shown that beta-glucans bind to a lectin domain within complement receptor type 3 (CR3), or to, more recently
Gordon D Ross   +3 more
doaj   +1 more source

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

open access: yesAdvanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang   +8 more
wiley   +1 more source

A Synthetic β‐Mannan Epitope Enables Immunization and Detection of Candida auris

open access: yesAngewandte Chemie, EarlyView.
A synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Emelie E. Reuber   +8 more
wiley   +2 more sources

Oat beta-glucan: health benefits and quantification methods

open access: yesInternational Journal of Food Properties
Beta-glucans are linear polysaccharides composed of glucopyranose units linked by β-(1,3) and β-(1,4) linkages found in cereals. These polysaccharides are known to be associated with various health benefits, including the reduction of blood cholesterol ...
Duc Doan Nguyen   +7 more
doaj   +1 more source

Detection of Beta-Glucan Contamination in Nanotechnology-Based Formulations

open access: yesMolecules, 2020
Understanding the potential contamination of pharmaceutical products with innate immunity modulating impurities (IIMIs) is essential for establishing their safety profiles.
Barry W. Neun   +4 more
doaj   +1 more source

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