Evolutionary ecology of beta‐lactam gene clusters in animals [PDF]
Molecular Ecology, 2017 Beta-lactam biosynthesis was thought to occur only in fungi and bacteria, but we recently reported the presence of isopenicillin N synthase in a soil-dwelling animal, Folsomia candida.
Wouter Suring +10 more
semanticscholar +3 more sources
Expert opinion: The clinical usefulness of skin tests prior to the administration of beta-lactam antibiotics [PDF]
, 2022 An allergy skin test is used to diagnose certain allergies by identifying sensitized allergens. In other words, it is a test for patients who are already sensitized to certain allergens.
박혜정, 이재현
core +1 more source
Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation:Development and External Validation of Three Novel (Machine Learning) Models [PDF]
, 2023 In the intensive care unit (ICU), infection-related mortality is high. Although adequate antibiotic treatment is essential in infections, beta-lactam target non-attainment occurs in up to 45% of ICU patients, which is associated with a lower likelihood ...
+12 more
core +1 more source
Investigation of beta-lactam antibiotics residues in fresh cow\u27s milk [PDF]
, 2023 The presence of beta-lactam antibiotics in milk as raw material for other dairy products is prohibited by legal regulations. The research on the presence of beta-lactam antibiotics in milk was done during the six months (January – June) 2021, including ...
Bytyçi, Xhavit +4 more
core +2 more sources
Procalcitonin Predicts Response to Beta-Lactam Treatment in Hospitalized Children with Community-Acquired Pneumonia [PDF]
, 2012 BACKGROUND: Antibiotic treatment of community-acquired pneumonia (CAP) in children remains mostly empirical because clinical and paraclinical findings poorly discriminate the principal causes of CAP.
Alexander Leis +39 more
core +14 more sources
Image-based dynamic phenotyping reveals genetic determinants of filamentation-mediated beta-lactam tolerance [PDF]
, 2020 Antibiotic tolerance characterized by slow killing of bacteria in response to a drug can lead to treatment failure and promote the emergence of resistance.
Camacho, Rafael +8 more
core +2 more sources
Effect of β-lactamase inhibitors on in vitro activity of β-lactam antibiotics against Burkholderia cepacia complex species [PDF]
, 2016 Background: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of beta-
Coenye, Tom, Everaert, Annelien
core +2 more sources
The Infectious Disease Ontology in the Age of COVID-19 [PDF]
, 2021 The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane +3 more
core +1 more source
An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]
, 2018 Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
core +1 more source
Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing [PDF]
, 2022 Free PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431576/The increasing threat of drug resistance and a stagnated pipeline of novel therapeutics endanger the eradication of tuberculosis.
Anes, Elsa +8 more
core +1 more source