Results 71 to 80 of about 63,634 (227)
British Journal of Clinical Pharmacology, EarlyView.Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti +9 more
wiley +1 more source
NH‐Sulfilimine Synthesis Catalyzed by Nonheme Iron(II) Complex
ChemistryEurope, EarlyView.Sulfilimines are emerging as valuable functional group in modern medicinal chemistry. Yet, their catalytic preparation is underexplored compared to sulfoximines. Here, the iron‐catalyzed synthesis of 14 examples of unprotected sulfilimines in good yields, under aerobic atmosphere and at room temperature, is described.
Léa Tesson +2 more
wiley +1 more source
PLoS Pathogens, 2009 It has long been recognized that the modification of penicillin-binding proteins (PBPs) to reduce their affinity for beta-lactams is an important mechanism (target modification) by which Gram-positive cocci acquire antibiotic resistance.
Bartolomé Moya +6 more
doaj +1 more source
Phenotypic expression of resistance to penicillinase-stable beta-lactams in Staphylococcus aureus: growth rate, cross wall morphogenesis, and cell division cycle [PDF]
, 1982 F Rozgonyi
openalex +1 more source
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, EarlyView.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Periodontology 2000, EarlyView., 2023 Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
BMC Research Notes, 2019 Objective Extended spectrum β-lactamases (ESBL) producing Enterobacteriaceae predominantly E. coli and K. pneumoniae bacteremia have limited treatment options and high mortality.
Nosheen Nasir +4 more
doaj +1 more source
European Journal of Organic Chemistry, EarlyView.The absorption spectra of amoxicillin degradation by colloidal MnO2 in the presence and absence of surfactants. Herein, the oxidative degradation of amoxicillin (AMX) by water‐soluble colloidal MnO2 is investigated spectrophotometrically at 298 K in both uncatalyzed and nonionic micellar‐catalyzed media (Triton X‐100 and Brij‐35).
Neelam Sen +4 more
wiley +1 more source