Results 31 to 40 of about 154,226 (253)
Live to cheat another day: bacterial dormancy facilitates the social exploitation of beta-lactamases [PDF]
, 2015 The breakdown of antibiotics by β-lactamases may be cooperative, since resistant cells can detoxify their environment and facilitate the growth of susceptible neighbours. However, previous studies of this phenomenon have used artificial bacterial vectors
A Bloor +52 more
core +1 more source
Angewandte Chemie, EarlyView.Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg +21 more
wiley +2 more sources
The effect of imipenem and diffusible signaling factors on the secretion of outer membrane vesicles and associated Ax21 proteins in Stenotrophomonas maltophilia [PDF]
, 2015 Outer membrane vesicles (OMVs) are small nanoscale structures that are secreted by bacteria and that can carry nucleic acids, proteins, and small metabolites. They can mediate intracellular communication and play a role in virulence.
Bart eDevreese +9 more
core +5 more sources
Mechanism of resistance to beta-lactam antibiotics
BULLETIN of the L.N. Gumilyov Eurasian National University. BIOSCIENCE Series, 2023 Acinetobacter baumannii is the most commonly associated human pathogen with infections in the genus. This opportunistic pathogen causes quite serious infections, especially in fond patients, and has the ability to quickly develop resistance to new antibiotics. In the recent past, carbapenems, a.
R. Khalilov +2 more
openaire +1 more source
Angewandte Chemie, EarlyView.Targeted covalent inhibitors (TCI) containing cyclic imine warheads react with tyrosine and tryptophan residues via the Mannich reaction. These cyclic imine warheads show comparable reaction kinetics to cysteine‐reactive electrophiles commonly used in TCIs.
Sijie Wang +6 more
wiley +2 more sources
Characterization of extended-spectrum β-lactamases produced by Escherichia coli isolated from hospitalized and nonhospitalized patients : emergence of CTX-M-15-producing strains causing urinary tract infections [PDF]
, 2010 Extended-spectrum β-lactamase-producing Escherichia coli isolates were obtained from hospitalised and non-hospitalised patients in Belgium between August 2006 and November 2007.
Butaye, Patrick +10 more
core +1 more source
Frontiers in Veterinary Science, 2019 Quantitative data on fecal shedding of antimicrobial-resistant bacteria are crucial to assess the risk of transmission from dogs to humans. Our first objective was to investigate the prevalence of quinolone/fluoroquinolone-resistant and beta-lactam ...
V. Dupouy +12 more
semanticscholar +1 more source
beta-Lactamases and beta-lactam resistance in Escherichia coli [PDF]
Antimicrobial Agents and Chemotherapy, 1985 Escherichia coli strains determining 17 different plasmid-determined beta-lactamases were tested for resistance to new broad-spectrum beta-lactam antibiotics. Several beta-lactamases demonstrated enhanced resistance to cefamandole but only low-level resistance to other agents. High production of cloned E.
G. Jacoby, L. Sutton
semanticscholar +3 more sources
Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine feces [PDF]
, 2007 The aim of this study was to assess the impact of three ampicillin dosage regimens on ampicillin resistance among Enterobacteriaceae recovered from swine feces using phenotypic and genotypic approaches.
Bibbal, Delphine +6 more
core +5 more sources
PLoS ONE, 2019 The goal of this work was to study the phenotypic susceptibility and resistance determinants of N. gonorrhoeae isolates to beta-lactam antimicrobials (benzylpenicillin and ceftriaxone).
B. Shaskolskiy +9 more
semanticscholar +1 more source