Results 1 to 10 of about 1,103,793 (328)

Antibacterial activity of Syzygium aromaticum (clove) against uropathogens producing ESBL, MBL, and AmpC beta-lactamase: Are we close to getting a new antibacterial agent?

Journal of Family Medicine and Primary Care, 2020
Introduction: The present study was done to access the antibacterial activity of clove (Syzygium aromaticum) against extended-spectrum beta-lactamase (ESBL), metallo-beta-lactamase (MBL), and AmpC beta-lactamase-producing gram-negative bacteria causing ...
Sameer S Faujdar, Dakshina Bisht, Amisha Sharma   +2 more
doaj   +2 more sources

Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor

Nature Communications, 2020
Beta-lactam antibiotics and beta-lactamase inhibitors compete for the same binding site on beta-lactamases; thus, mutations that increase beta-lactamase activity likely increase also susceptibility to the inhibitor. Here, Russ et al.
Dor Russ, Fabian Glaser, Einat Shaer Tamar, Idan Yelin, Michael Baym, Eric D. Kelsic, Claudia Zampaloni, Andreas Haldimann, Roy Kishony   +8 more
doaj   +2 more sources

Beta-Lactamase [PDF]

Definitions, 2020
3
A. Kovačević, David, R. M. Smith, E. Rahbé, S. Novelli, Paul Henriot, L. Temime, L. Opatowski   +7 more
semanticscholar   +2 more sources

Extended spectrum and metalo beta-lactamase producing airborne Pseudomonas aeruginosa and Acinetobacter baumanii in restricted settings of a referral hospital: a neglected condition

Antimicrobial Resistance and Infection Control, 2017
Background Frequently encountered multidrug-resistant bacterial isolates of P. aeruginosa and A. baumannii are common and prevalent in a hospital environment.
Fithamlak Bisetegen Solomon, Fiseha Wadilo, Efrata Girma Tufa, Meseret Mitiku   +3 more
doaj   +2 more sources

Beta-lactamase induction and cell wall metabolism in Gram-negative bacteria

Frontiers in Microbiology, 2013
Production of beta-lactamases, the enzymes that degrade beta-lactam antibiotics, is the most widespread and threatening mechanism of antibiotic resistance.
Ximin eZeng, Jun eLin
doaj   +2 more sources

Prevalence of extended-spectrum beta-lactamases, AmpC beta-lactamase, and metallo-beta-lactamase producing Pseudomonas aeruginosa and Acinetobacter baumannii in an intensive care unit in a tertiary care hospital

Journal of the Scientific Society, 2013
Background: Resistance to broad-spectrum beta-lactams, mediated by extended-spectrum beta-lactamases (ESBL), AmpC beta-lactamase, and metallo-beta-lactamase (MBL) enzymes, is an increasing problem worldwide. Aim of the study: This study was undertaken to
Varun Goel, Sumati A Hogade, S G Karadesai   +2 more
doaj   +2 more sources

Molecular characterization of the whole genome in clinical multidrug-resistant strains of Klebsiella pneumoniae

Journal of Infection in Developing Countries, 2023
Introduction: Antimicrobial resistance (AMR) is a major public health concern. The spread of AMR-encoding genes between enterobacteria, especially in Klebsiella pneumoniae strains, lead to failure in the treatment of most individuals.
Amina Rahmani, Laarem Meradi, Rudolph Piris   +2 more
doaj   +1 more source

Old and New Beta-Lactamase Inhibitors: Molecular Structure, Mechanism of Action, and Clinical Use

Antibiotics, 2021
The β-lactams have a central place in the antibacterial armamentarium, but the increasing resistance to these drugs, especially among Gram-negative bacteria, is becoming one of the major threats to public health worldwide.
D. Carcione, Claudia Siracusa, A. Sulejmani, V. Leoni, J. Intra   +4 more
semanticscholar   +1 more source

Ampicillinase C Beta-lactamase Producers among Isolates of Enterobacteriaceae in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: Ampicillinase C beta-lactamase-producing organisms are often resistant to multiple antimicrobial agents, and therapeutic options against these pathogens are limited. Limited information is available regarding Ampicillinase C beta-lactamase
Shusila Khadka, Achut Barakoti, Ram Prasad Adhikari, Laxmi Kant Khanal, Jyotshna Sapkota   +4 more
doaj   +1 more source

P-1707. Rapid Detection of Extended-Spectrum Beta-Lactamase-Producing Bacteria Using MBT STAR-Cepha® Technology [PDF]

Open Forum Infect Dis
Victoria Petty, Brent Nelson, Ashley Rogers, Heather Fillmore, Bert K. Lopansri   +4 more
europepmc   +3 more sources