Results 91 to 100 of about 29,386 (262)

The small protein CydX is required for function of cytochrome bd oxidase in Brucella abortus. [PDF]

, 2012
A large number of hypothetical genes potentially encoding small proteins of unknown function are annotated in the Brucella abortus genome. Individual deletion of 30 of these genes identified four mutants, in BAB1_0355, BAB2_0726, BAB2_0470, and BAB2_0450
de Jong, Maarten F, den Hartigh, Andreas B, Rolán, Hortensia G, Roux, Christelle M, Sun, Yao-Hui, Tsolis, Renée M   +5 more
core   +3 more sources

Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference

Microbiota Medicine Research, EarlyView.
ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang, Sunny Hei Wong, Gaochen Lu, Zheshun Pi, Ting Zhang, Hon Ho Yu, Nan Bu, Xiong Chen, Bota Cui, Dafa Ding, Hainv Gao, Suyu He, Xingxiang He, Shengjuan Hu, Jia Hu, Yunlian Hu, Xiaomeng Jiang, Jiang Jin, Jingnan Li, Pan Li, Juan Liao, Weiwei Liao, Jiang Liu, Ling Liu, Yaping Liu, Yanyan Liu, Yu Liu, Muhan Lv, Xiangjun Meng, Yongzhan Nie, Qian Ren, Lixuan Sang, Yang Sun, Xiaowen Tang, Liangjing Wang, Wei Wang, Xin Wang, Yanling Wei, Quan Wen, Lihao Wu, Xia Wu, Fang Xiao, Lijing Xiong, Shaoqi Yang, Song Yang, Guoliang Ye, Yue Zeng, Huihong Zhai, Xiaoqian Zhang, Yu Zhang, Kun Zhao, Li Zhou, Li Zhu, Kaichun Wu   +53 more
wiley   +1 more source

THE NEW METALL-BETA-LACTAMASE’S INHIBITOR EFFICACY IN A MODEL SYSTEM IN VITRO

Инфекция и иммунитет, 2017
The Enterobacteriaceae antibiotics resistance depends on a combination of several mechanisms, such as the beta-lactamases overproduction, the microbial cell reduction outer membrane permeability (usually associated with loss of protein porin), the ...
A. G. Afinogenova, T. M. Voroshilova, G. E. Afinogenov, D. Yu. Maday   +3 more
doaj   +1 more source

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

Veterinary Record, EarlyView.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker, Dan O'Neill, Huw Stacey, Dave Brodbelt   +3 more
wiley   +1 more source

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

Veterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins, Peers Davies, Peter‐John Noble, Anna Bunford‐Davies, April Lawson, Gina Pinchbeck, Ifan Lloyd, Robert Smith, Alan D. Radford   +8 more
wiley   +1 more source

Multiple Drug-Resistant CLABSI from an Extremely Rare Bacterium, Chryseobacterium gleum

Case Reports in Infectious Diseases, 2020
Chryseobacterium gleum is a lactose nonfermenting Gram-negative bacillus (NFGNB) found in soil, plants, and some water sources but rarely implicated as a human pathogen.
David Anson, Benjamin Chaucer, Joseph Norton, Saurabh Bansal   +3 more
doaj   +1 more source

Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]

, 2016
This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...
Armstrong, Jon, Arrieta, Antonio, Bishai, Raafat, Bradley, John S, Das, Shampa, Delair, Shirley, Edeki, Timi, Holmes, William C, Li, Jianguo, Moffett, Kathryn S, Mukundan, Deepa, Perez, Norma, Romero, José R, Speicher, David, Sullivan, Janice E, Zhou, Diansong   +15 more
core  

The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]

, 2016
Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie, Devos, Simon, Devreese, Bart   +2 more
core   +2 more sources

A novel fusion tool to enable G protein‐coupled receptor structure determination

Acta Crystallographica Section D, EarlyView.
The development of a new fusion tool in which a β‐lactamase fusion tag and a binding partner enabled the structure determination of an antagonist‐bound G protein‐coupled receptor by cryo‐EM is reported.Structure determination of G protein‐coupled receptors (GPCRs) plays an important role in accelerating drug development against this medically important
Nita R. Shah, Mathieu Oosterlaken, Claudine Bisson, Mattia Bertinelli, Alicia M. Churchill-Angus, Andrew Hutchin, Jola Kopec, Vadim Kotov, Ciaran R. McFarlane, Erika Griss Pascualli, Ana Pavic, Matthias Zebisch, Cédric Fiez-Vandal, Edoardo Fabini, Stéphanie Duclos   +14 more
wiley   +1 more source

Cefdinir binding to a class A β‐lactamase revealed by serial cryo‐crystallography

Acta Crystallographica Section D, EarlyView.
Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gargi Gore, Andreas Prester, Kim Bartels, David von Stetten, Eike C. Schulz   +4 more
wiley   +1 more source