Results 81 to 90 of about 1,353,519 (253)
A retrospective analysis of bacterial pathogens in wounds in an equine hospital (2017–2022)
Equine Veterinary Education, EarlyView.Summary Background Bacterial infections are a major cause of morbidity in horses, particularly in soft tissue wounds (STW) and surgical site infections (SSI). Rising antimicrobial resistance poses challenges for timely treatment. Knowledge of common pathogens and their resistance patterns is therefore essential.
J. Nebes +3 more
wiley +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley +1 more source
Multiple Drug-Resistant CLABSI from an Extremely Rare Bacterium, Chryseobacterium gleum
Case Reports in Infectious Diseases, 2020 Chryseobacterium gleum is a lactose nonfermenting Gram-negative bacillus (NFGNB) found in soil, plants, and some water sources but rarely implicated as a human pathogen.
David Anson +3 more
doaj +1 more source
Diketene analogs as .BETA.-lactamase inhibitor.
Chemical and Pharmaceutical Bulletin, 1989 Compounds having a structural analogy with diketene have been synthesized and their potencies as beta-lactamase inhibitors have been studied. Among six compounds so far tested, alpha-phenyl-beta-benzylidene-3-propanolide was shown to be an irreversible inhibitor of the enzyme. The availability of simple monocyclic compounds as beta-lactamase inhibitors
YANIZAWA, Kazutaka +2 more
openaire +3 more sources
Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]
, 2007 The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core
Nanomolar inhibitors of AmpC beta-lactamase
, 2003 beta-lactamases are the most widespread resistance mechanism to beta-lactam antibiotics, such as the penicillins and the cephalosporins. In an effort to combat these enzymes, a combination of stereoselective organic synthesis, enzymology, microbiology ...
MORANDI, federica +6 more
core +1 more source
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
Journal of Periodontal Research, EarlyView.This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
Exploring the secrets of virus entry: the first respiratory syncytial virus carrying beta lactamase
Frontiers in MicrobiologyBackgroundRespiratory Syncytial Virus (RSV) presents a significant health threat, especially to young children. In-depth understanding of RSV entry mechanisms is essential for effective antiviral development.
Marcio De Ávila-Arias +12 more
doaj +1 more source
Impact of the New Delhi metallo-beta-lactamase on beta-lactam antibiotics
, 2015 Monika T Zmarlicka,1 Michael D Nailor,2 David P Nicolau3 1Department of Pharmacy, Hartford Hospital, Hartford, 2School of Pharmacy, Department of Pharmacy Practice, University of Connecticut, Storrs, 3Center for Anti-Infective Research and Development ...
Zmarlicka MT, Nicolau DP, Nailor MD
core
Background/Objectives: The emergence of hypervirulent Pseudomonas aeruginosa strains resistant to β-lactamase inhibitor antibiotics is a critical health problem as they impede the treatment of infections. The objective of this study was to determine
Elizabeth Olvera-Navarro +19 more
core +1 more source