Results 21 to 30 of about 153,861 (252)

Anti-beta 2 glycoprotein I antibodies in centenarians [PDF]

Experimental Gerontology, 2004
Non-organ-specific autoantibodies are present in centenarians without evidence of autoimmune diseases but conflicting or no data on anti-phospholipid and anti-phospholipid binding proteins were reported.To investigate the presence and antigen specificity of anti-phospholipid and anti-phospholipid binding proteins in centenarians.Seventy-seven ...
Meroni P. L., Mari D., Monti D., Coppola R., CAPRI, MIRIAM, SALVIOLI, STEFANO, Tincani A., Gerli R., FRANCESCHI, CLAUDIO   +8 more
openaire   +5 more sources

Dimers of β2-Glycoprotein I Mimic thein Vitro Effects of β2-Glycoprotein I-Anti-β2-glycoprotein I Antibody Complexes [PDF]

Journal of Biological Chemistry, 2001
Anti-beta(2)-glycoprotein I antibodies are thought to cause lupus anticoagulant activity by forming bivalent complexes with beta(2)-glycoprotein I (beta(2)GPI). To test this hypothesis, chimeric fusion proteins were constructed of the dimerization domain (apple 4) of factor XI and beta(2)GPI.
Lutters, B. C., Meijers, J. C., Derksen, R. H., Arnout, J., de Groot, P. G.   +4 more
openaire   +3 more sources

Budd-Chiari Syndrome as an Initial Presentation of Antiphospholipid Syndrome in a Male [PDF]

Journal of Clinical and Diagnostic Research, 2022
In Budd-Chiari Syndrome (BCS) there is narrowing and obstruction of the veins of the hepatic veins. Patients have upper quadrant abdominal pain, hepatomegaly and/or ascites.
Pusala Varun Narayana, Prasanna Kumar Satpathy, S Bharath Gowda, Srivatsav Addepalli   +3 more
doaj   +1 more source

Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching

Frontiers in Immunology, 2023
BackgroundThrombosis is a unique complication of coronavirus disease 2019 (COVID-19). Although antiphospholipid antibodies (aPL) are detected in COVID-19 patients, their clinical significance remains elusive.
Seiya Oba, Tadashi Hosoya, Risa Kaneshige, Daisuke Kawata, Taiki Yamaguchi, Takahiro Mitsumura, Takahiro Mitsumura, Sho Shimada, Sho Shibata, Tomoya Tateishi, Ryuji Koike, Shuji Tohda, Akihiro Hirakawa, Nukui Yoko, Nukui Yoko, Yasuhiro Otomo, Junzo Nojima, Yasunari Miyazaki, Shinsuke Yasuda   +18 more
doaj   +1 more source

Morphology, biophysical properties and protein-mediated fusion of archaeosomes. [PDF]

PLoS ONE, 2012
As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds.
Vid Šuštar, Jasna Zelko, Patrizia Lopalco, Simona Lobasso, Ajda Ota, Nataša Poklar Ulrih, Angela Corcelli, Veronika Kralj-Iglič   +7 more
doaj   +1 more source

Anticardiolipin and anti-beta-2-glycoprotein I antibodies

Autoimmunity, 2005
The anticardiolipin (aCL) antibody test was first established in 1983, using cardiolipin (negatively charged phospholipid) as an antigen in a solid-phase immunoassAy. It was first applied to the study of systemic lupus erythematosus patients, and was found associated with thromboses and recurrent pregnancy losses.
Marai I, TINCANI, Angela, Balestrieri G, Shoenfeld Y.   +3 more
openaire   +3 more sources

beta 2-Glycoprotein I and anti-beta 2-glycoprotein I antibodies: where are we now? [PDF]

Rheumatology, 1997
beta 2-Glycoprotein I (beta 2-GPI), a plasma protein with in vitro anticoagulant properties, has been recognized to have an important role in the antiphospholipid syndrome (APS) as a cofactor and an (co)antigen in ELISA assays. Although beta 2-GPI levels were found to be increased in some patients with APS, the clinical value of measuring beta 2-GPI ...
openaire   +1 more source

Prevalence of beta 2-glycoprotein I antibody in systemic lupus erythematosus patients with beta 2-glycoprotein I dependent antiphospholipid antibodies. [PDF]

Annals of the Rheumatic Diseases, 1995
To investigate whether beta 2-glycoprotein I antibody (aGPI) exists in sera that are positive for antiphospholipid antibodies (aPL).Thirty six patients with systemic lupus erythematosus (SLE) and 20 healthy volunteers were recruited. GPI independent and dependent aPL (anticardiolipin (aCL), antiphosphatidylserine, antiphosphatidylinositol ...
J, Matsuda, N, Saitoh, M, Gotoh, K, Gohchi, M, Tsukamoto   +4 more
openaire   +2 more sources

In vivo modulation of angiogenesis by beta 2 glycoprotein I [PDF]

Journal of Autoimmunity, 2010
Beta 2 glycoprotein I (β2GPI) is the major auto antigen in the antiphospholipid syndrome but also interacts with fibrinolytic and angiogenic proteins. The aim of this study was to examine the angiogenic potential of β2GPI in vivo in β2GPI deficient mice utilizing angiogenic assays. β2GPI deficient mice show increased microvessel formation in comparison
Passam, F.H, Qi, Jian, Tanaka, K, Matthaei, Klaus, Krilis, Steven   +4 more
openaire   +3 more sources

Antiphospholipid Antibodies and Antiphospholipid Syndrome During Pregnancy: Diagnostic Concepts

Frontiers in Immunology, 2015
Antiphospholipid syndrome comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies. APS was described in the context of lupus and later as an isolated syndrome or primary APS.
Roger A Levy, Flavia eCunha, Guilherme R de Jesús, Nilson R de Jesús   +3 more
doaj   +1 more source