Results 31 to 40 of about 163,662 (341)
Loss of pancreas upon activated Wnt signaling is concomitant with emergence of gastrointestinal identity [PDF]
, 2016 Organ formation is achieved through the complex interplay between signaling pathways and transcriptional cascades. The canonical Wnt signaling pathway plays multiple roles during embryonic development including patterning, proliferation and ...
Cano, David A. +7 more
core +8 more sources
Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma. [PDF]
, 2015 Adamantinomatous craniopharyngiomas (ACPs) are the most common pituitary tumours in children. Although histologically benign, these are clinically aggressive tumours, difficult to manage and associated with poor quality of life for the patients.
Martinez-Barbera, JP
core +1 more source
Journal of Oral and Maxillofacial Pathology, 2016 In continuation with the previous review on "β-catenin in health", in this review we discuss the role of β-catenin in the pathogenesis of common oral lesions in the oral and maxillofacial region- oral potentially malignant disorders, their progression to oral squamous cell carcinoma, salivary gland tumors and odontogenic tumours.
Prakash, Sharada +3 more
openaire +3 more sources
Smad7:β-catenin Complex Regulates Myogenic Gene Transcription [PDF]
, 2019 Recent reports indicate that Smad7 promotes skeletal muscle differentiation and growth. We previously documented a non-canonical role of nuclear Smad7 during myogenesis, independent of its role in TGF-β signaling.
McDermott, John +2 more
core +1 more source
Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling. [PDF]
PLoS ONE, 2009 Deviation from proper muscle development or homeostasis results in various myopathic conditions. Employing genetic as well as chemical intervention, we provide evidence that a tight regulation of Wnt/beta-catenin signaling is essential for muscle fiber ...
Jin-Ming Tee +3 more
doaj +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
CTNNB1 (catenin, beta-1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on CTNNB1 (catenin, beta-1), with data on DNA, on the protein encoded, and where the gene is implicated.
B Debuire, A Lemoine, R Saffroy
openaire +1 more source
eLife, 2019 Beta-catenin (i.e., canonical Wnt) signaling controls CNS angiogenesis and the blood-brain and blood-retina barriers. To explore the role of the Discs large/membrane-associated guanylate kinase (Dlg/MAGUK) family of scaffolding proteins in beta-catenin ...
Chris Cho +4 more
doaj +1 more source
E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]
, 2015 Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke +27 more
core +2 more sources
Beta catenin mutated hepatic adenoma
, 2015 Matt Morgan, Joshua Yap, Jeremy Jones
openalex +2 more sources