Results 221 to 230 of about 211,042 (267)

A theoretical analysis of the power of biased coin designs [PDF]

Journal of Statistical Planning and Inference, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Alessandro Baldi Antognini
exaly   +5 more sources

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Power efficiency of Efron’s biased coin design

Journal of Statistical Planning and Inference, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
David Azriel
exaly   +3 more sources

Balance and randomness in sequential clinical trials: the dominant biased coin design [PDF]

Pharmaceutical Statistics, 2014
AbstractEfron's biased coin design (BCD) is a well‐known randomization technique that helps neutralize selection bias, while keeping the experiment fairly balanced for every sample size. Several extensions of this rule have been proposed, and their properties were analyzed from an asymptotic viewpoint and compared via simulations in a finite setup. The
BALDI ANTOGNINI, ALESSANDRO, ZAGORAIOU, MAROUSSA   +1 more
semanticscholar   +4 more sources

Biased coin design with imbalance tolerance

Stochastic Models, 1999
Summary: One of the main aspects of a sampling procedure is to determine how to collect samples. A completely random sampling scheme is free of any bias and provides a basis for valid statistical inferences. A balanced sampling scheme strengthens efficiency in statistical inference procedures.
Chen Yung-Pin
exaly   +3 more sources

Saddlepoint approximation p-values of weighted log-rank tests based on censored clustered data under block Efron’s biased-coin design

Statistical Methods in Medical Research, 2023
Clustered survival data frequently occurs in biomedical research fields and clinical trials. The log-rank tests are used for two independent samples of clustered data tests.
Haidy A Newer
exaly   +2 more sources

Covariate-adjusted inference for doubly adaptive biased coin design

Statistical Methods in Medical Research
Randomized controlled trials (RCTs) are pivotal for evaluating the efficacy of medical treatments and interventions, serving as a cornerstone in clinical research. In addition to randomization, achieving balances among multiple targets, such as statistical validity, efficiency, and ethical considerations, is also a central issue in RCTs.
Fuyi Tu, Wei Ma
openaire   +3 more sources

Adaptive biased-coin designs for clinical trials with several treatments [PDF]

Discussiones Mathematicae Probability and Statistics, 2023
Summary: Adaptive designs are used in phase III clinical trials for skewing the allocation pattern towards the better treatments. We use optimum design theory to provide a skewed biased-coin procedure for sequential designs with continuous responses.
Atkinson, Anthony
openaire   +3 more sources

Asymptotic Properties of Biased Coin Designs for Treatment Allocation [PDF]

, 2004
Biased coin designs (BCD) are a special type of randomized sequential experiments. A common feature of several BCD’s is their Markov property, which allows a direct study of the design asymptotics. Possible criteria for comparing different biased coin designs are discussed with reference to particular cases.
GIOVAGNOLI, ALESSANDRA
openaire   +3 more sources