Bias and loss: the two sides of a biased coin [PDF]
The paper assesses biased-coin designs for sequential treatment allocation in clinical trials. Comparisons emphasise the importance of considering randomness, as well as treatment balance, which are calculated as bias and loss. In the numerical examples,
Anthony C. Atkinson +1 more
core +1 more source
Item Selection With Biased-Coin Up-and-Down Designs [PDF]
Targeting any arbitrary percentile, the biased-coin up-and-down design is theoretically appealing and can provide an efficient alternative to the current maximum Fisher information method for item selection in adaptive testing. This paper illustrates the
Zhaohui Sheng, Yanyan Sheng
core
ED90 of spinal 2-chloroprocaine 1% in ambulatory knee arthroscopy up to 45 min: a randomized biased-coin- up-and-down sequential allocation trial [PDF]
BACKGROUND: A short acting spinal anesthetic facilitates smooth flow since quick recovery of motor function will facilitate unassisted ambulation. The aim of this study was to estimate the effective dose (ED90) of intrathecal 2-chloroprocaine 1% in ...
Swart, Eleonora L +12 more
core +1 more source
Optimal response and covariate-adaptive biased-coin designs for clinical trials with continuous multivariate or longitudinal responses [PDF]
Adaptive randomization of the sequential construction of optimum experimental designs is used to derive biased-coin designs for longitudinal clinical trials with continuous responses.
Biswas, Atanu, Atkinson, Anthony C.
core +1 more source
Central Limit Theorems for Doubly Adaptive Biased Coin Designs
Subjects are assumed to arrive sequentially at an experimental site and are immediately assigned to one of two treatments \(A\) or \(B\). Responses from the subjects for the treatments are assumed to be independent random variables from exponential families. Let \(\rho\) denote the desired allocation proportion under Eiseles biased coin design [\textit{
Eisele, Jeffrey R. +1 more
openaire +2 more sources
A doubly adaptive biased coin design. [PDF]
A doubly adaptive biased coin design is formulated for the allocation of patients to treatments A and B in a clinical trial. The design is doubly adaptive in the sense that it takes account of the proportion of patients assigned to each treatment and the
Eisele, Jeffrey Robert
core
Biased Judgements of Euro Coins’ sizes: Stimuli-specific and Interindividual Suggestive Effects [PDF]
Suggestibility regarding the biased estimations of Euro coins from alleged different countries was examined. It was predicted that images regarding different nations would affect these estimations.
Molz, Günter
core +1 more source
Spin and Charge Control of Topological End States in Chiral Graphene Nanoribbons on a 2D Ferromagnet
Chiral graphene nanoribbons on a ferromagnetic gadolinium‐gold surface alloy display tunable spin and charge states at their termini. Atomic work function variations and exchange fields enabe transitions between singlet, doublet, and triplet configurations.
Leonard Edens +8 more
wiley +1 more source
Exact optimum coin bias in Efron's randomization procedure [PDF]
Efron’s biased coin design is a restricted randomization procedure that has very favorable balancing properties, yet it is fully randomized, in that subjects are always randomized to one of two treatments with a probability less than 1.
ZAGORAIOU, MAROUSSA +3 more
core +1 more source
This work develops bias‐triggered conductivity relaxation as a novel technique to study oxygen reactions in mixed ionic‐electronic conducting thin films by integrating electrochemical titration and electrical conductivity relaxation to achieve synchronous multi‐parameter characterization, providing simultaneous electronic, ionic, and extraordinarily ...
Alexander Stangl +4 more
wiley +1 more source

