Results 11 to 20 of about 19,462 (277)
The challenge of infectious diseases remains a critical concern to the global public health. Recently, it is common to encounter touch-screen electronic devices everywhere to access services.
Hailemichael Ayalew+6 more
doaj +1 more source
Mild Biamidine-Transfer Conditions for the Synthesis of Aliphatic Biguanides
This study focuses on the development of new synthetic pathways to monosubstituted biguanides from amines. An exhaustive comparison of the conditions and reagents used for biamidine transfer was performed.
Rostyslav Bardovskyi+3 more
doaj +1 more source
Synthesis of antibacterial polyether biguanide curing agent and its cured antibacterial epoxy resin
At present, bacteria continue to threaten human health, and the resistance of bacteria to antibiotics continues to increase, so the development of new antibacterial agents and antibacterial materials is increasingly important to ensure human health.
Rui Li+6 more
doaj +1 more source
Synthesis, Characterization and Structural Analysis of Two New Biguanide Complexes
This study reports on the synthesis and characterization of two new coordination compounds of the active pharmaceutical ingredient metformin and transition metals.
Andrea Pastrana-Dávila+4 more
doaj +1 more source
Antimicrobial resistance is a critical public health issue that requires a thorough understanding of the factors that influence the selection and spread of antibiotic-resistant bacteria.
Raphaël Charron+9 more
doaj +1 more source
Repurposing Metabolic Inhibitors in the Treatment of Colon Adenocarcinoma Patient-Derived Models
The effect of agonists on AMP-activated protein kinase (AMPK), mainly metformin and phenformin, has been appreciated in the treatment of multiple types of tumors.
Bora Lee+5 more
doaj +1 more source
The Effect of Metformin as an Adjunct Therapy in Adolescents with Type 1 Diabetes [PDF]
Introduction: The strict control of blood glucose levels in adolescents with Type 1 Diabetes Mellitus (T1DM) is accompanied with a considerable long term decrease in microvasular and macrovascular complications.
Aria Setoodeh+6 more
doaj +1 more source
Mono- and Dinuclear Aluminium Complexes Derived from Biguanide and Carbothiamide Ligands
Dianionic N,N-chelating ligands play a crucial role in coordination chemistry, but reports on related complexes remain limited to certain types of ligands.
Maximilian Dehmel+2 more
doaj +1 more source
Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània+6 more
core +2 more sources
The lack of in-depth knowledge about the molecular determinants of glioblastoma (GBM) occurrence and progression, combined with few effective and BBB crossing-targeted compounds represents a major challenge for the discovery of novel and efficacious ...
Federica Barbieri+9 more
doaj +1 more source