Results 11 to 20 of about 19,462 (277)

Biguanide- and Oligo(Ethylene Glycol)-Functionalized Poly(3,4-Ethylenedioxythiophene): Electroactive, Antimicrobial, and Antifouling Surface Coatings

open access: yesFrontiers in Chemistry, 2022
The challenge of infectious diseases remains a critical concern to the global public health. Recently, it is common to encounter touch-screen electronic devices everywhere to access services.
Hailemichael Ayalew   +6 more
doaj   +1 more source

Mild Biamidine-Transfer Conditions for the Synthesis of Aliphatic Biguanides

open access: yesSynOpen, 2021
This study focuses on the development of new synthetic pathways to monosubstituted biguanides from amines. An exhaustive comparison of the conditions and reagents used for biamidine transfer was performed.
Rostyslav Bardovskyi   +3 more
doaj   +1 more source

Synthesis of antibacterial polyether biguanide curing agent and its cured antibacterial epoxy resin

open access: yesDesigned Monomers and Polymers, 2021
At present, bacteria continue to threaten human health, and the resistance of bacteria to antibiotics continues to increase, so the development of new antibacterial agents and antibacterial materials is increasingly important to ensure human health.
Rui Li   +6 more
doaj   +1 more source

Synthesis, Characterization and Structural Analysis of Two New Biguanide Complexes

open access: yesCrystals, 2023
This study reports on the synthesis and characterization of two new coordination compounds of the active pharmaceutical ingredient metformin and transition metals.
Andrea Pastrana-Dávila   +4 more
doaj   +1 more source

Polyhexamethylene biguanide promotes adaptive cross-resistance to gentamicin in Escherichia coli biofilms

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Antimicrobial resistance is a critical public health issue that requires a thorough understanding of the factors that influence the selection and spread of antibiotic-resistant bacteria.
Raphaël Charron   +9 more
doaj   +1 more source

Repurposing Metabolic Inhibitors in the Treatment of Colon Adenocarcinoma Patient-Derived Models

open access: yesCells, 2023
The effect of agonists on AMP-activated protein kinase (AMPK), mainly metformin and phenformin, has been appreciated in the treatment of multiple types of tumors.
Bora Lee   +5 more
doaj   +1 more source

The Effect of Metformin as an Adjunct Therapy in Adolescents with Type 1 Diabetes [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: The strict control of blood glucose levels in adolescents with Type 1 Diabetes Mellitus (T1DM) is accompanied with a considerable long term decrease in microvasular and macrovascular complications.
Aria Setoodeh   +6 more
doaj   +1 more source

Mono- and Dinuclear Aluminium Complexes Derived from Biguanide and Carbothiamide Ligands

open access: yesInorganics, 2021
Dianionic N,N-chelating ligands play a crucial role in coordination chemistry, but reports on related complexes remain limited to certain types of ligands.
Maximilian Dehmel   +2 more
doaj   +1 more source

Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]

open access: yes, 2017
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània   +6 more
core   +2 more sources

Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity

open access: yesFrontiers in Oncology, 2019
The lack of in-depth knowledge about the molecular determinants of glioblastoma (GBM) occurrence and progression, combined with few effective and BBB crossing-targeted compounds represents a major challenge for the discovery of novel and efficacious ...
Federica Barbieri   +9 more
doaj   +1 more source

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