Synthesis of Biguanides as Potential hypoglycemic Agents: Some heterocyclic Derivatives [PDF]
, 1966 Synthesis of Biguanides as Potential hypoglycemic Agents: Some heterocyclic ...
Auditi Kumar Acharyya +2 more
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Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production [PDF]
, 2017 Metformin is widely prescribed as a first-choice antihyperglycemic drug for treatment of type 2 diabetes mellitus, and recent epidemiological studies showed its utility also in cancer therapy.
Josef Houstek +8 more
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Metformin and Other Biguanides in Oncology: Advancing the Research Agenda [PDF]
, 2010 Retrospective studies that may be impractical to confirm prospectively suggest that diabetics treated with metformin have a substantially reduced cancer burden compared with other diabetics.
Michael Pollak
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Pharmaceutics, 2021 Aging is considered a contributing factor to many diseases such as cardiovascular disease, Alzheimer’s disease, and hearing loss. Age-related hearing loss, also termed presbycusis, is one of the most common sensory impairments worldwide, affecting one in
Jacqueline Chester +10 more
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Mono- and Dinuclear Aluminium Complexes Derived from Biguanide and Carbothiamide Ligands
Inorganics, 2021 Dianionic N,N-chelating ligands play a crucial role in coordination chemistry, but reports on related complexes remain limited to certain types of ligands.
Maximilian Dehmel +2 more
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Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. [PDF]
, 2023 The molecular mode of action of biguanides, including the drug metformin, which is widely used in the treatment of diabetes, is incompletely characterized.
Blaza, James N +5 more
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Analyses of biguanides and related compounds in biological and environmental samples by HPLC [PDF]
, 2015 Biguanides are nitrogen containing compounds and classified as antidiabetic (metformin, phenformin, buformin), antimalarial (proguanil, cycloproguanil, 4-chlorophenyl biguanide), and antimicrobial (chlorhexidine, polyhexamethylene biguanide) drugs. These
Hussain, Iqbal +4 more
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Noninsulin pharmacological management of type 1 diabetes mellitus
Indian Journal of Endocrinology and Metabolism, 2011 The injectable nature and other shortcomings of insulin have stimulated interest in studying the noninsulin pharmacological therapies to manage type 1 diabetes mellitus (T1DM).
Vishvas Garg
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Antimicrobial Action of Biguanides on the Viability of Acanthamoeba Cysts and Assessment of Cell Toxicity [PDF]
, 2013 PURPOSE. To assess dose- and concentration-dependent rates of biguanides on the viability of Acanthamoeba cysts isolated from severe ulcerative keratitis, and to correlate cysticidal activites with cytotoxic profiles in corneal and endothelial cells ...
Mafra, Cecilia Sales Pires [UNIFESP] +6 more
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Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders
Molecules, 2016 Natural products have always been exploited to promote health and served as a valuable source for the discovery of new drugs. In this review, the great potential of natural compounds and medicinal plants for the treatment or prevention of cardiovascular ...
Birgit Waltenberger +4 more
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