Results 41 to 50 of about 22,636 (317)

Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders

open access: yesMolecules, 2016
Natural products have always been exploited to promote health and served as a valuable source for the discovery of new drugs. In this review, the great potential of natural compounds and medicinal plants for the treatment or prevention of cardiovascular ...
Birgit Waltenberger   +4 more
doaj   +1 more source

Noninsulin pharmacological management of type 1 diabetes mellitus

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
The injectable nature and other shortcomings of insulin have stimulated interest in studying the noninsulin pharmacological therapies to manage type 1 diabetes mellitus (T1DM).
Vishvas Garg
doaj   +1 more source

Biguanides exert antitumoral actions in pituitary tumor cells through AMPK-dependent and -independent mechanisms.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2019
CONTEXT Pituitary neuroendocrine tumors (PitNETs) comprise a commonly underestimated pathology in terms of incidence and associated morbimortality. Currently, an appreciable subset of patients is resistant or poorly responsive to the main current medical
M. Vazquez-Borrego   +16 more
semanticscholar   +1 more source

Risk of cardiovascular events from current, recent, and cumulative exposure to abacavir among persons living with HIV who were receiving antiretroviral therapy in the United States: a cohort study. [PDF]

open access: yes, 2017
BackgroundThere is ongoing controversy regarding abacavir use in the treatment of HIV infection and the risk of subsequent development of cardiovascular disease.
Baxi, Sanjiv M   +3 more
core   +3 more sources

Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans

open access: yeseLife, 2023
Biguanides, including the world’s most prescribed drug for type 2 diabetes, metformin, not only lower blood sugar, but also promote longevity in preclinical models.
Lucydalila Cedillo   +18 more
doaj   +1 more source

The Biguanides Metformin and Buformin in Combination with 2-Deoxy-glucose or WZB-117 Inhibit the Viability of Highly Resistant Human Lung Cancer Cells

open access: yesStem Cells International, 2019
The biguanides metformin (MET) and to a lesser extent buformin (BUF) have recently been shown to exert anticancer effects. In particular, MET targets cancer stem cells (CSCs) in a variety of cancer types but these compounds have not been extensively ...
J. Yakisich   +3 more
semanticscholar   +1 more source

Ueber Biguanid [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft, 1879
n ...
openaire   +2 more sources

Quantitative determination of 0.05 % chlorhexidine solution by capillary electrophoresis

open access: yesZaporožskij Medicinskij Žurnal, 2019
The aim of the work was to estimate the quantitative content of 0.05 % chlorhexidine solution by capillary electrophoresis. Materials and methods.
A. M. Sampiiev   +3 more
doaj   +1 more source

Type 2 Diabetes in Neuroendocrine Tumors: Are Biguanides and Statins Part of the Solution?

open access: yesJournal of Clinical Endocrinology and Metabolism, 2018
Context Biguanides and statins exert beneficial effects on various cancer types. Their precise effects and underlying molecular mechanisms are poorly understood.
A. Herrera-Martínez   +6 more
semanticscholar   +1 more source

Mild Biamidine-Transfer Conditions for the Synthesis of Aliphatic Biguanides

open access: yesSynOpen, 2021
This study focuses on the development of new synthetic pathways to monosubstituted biguanides from amines. An exhaustive comparison of the conditions and reagents used for biamidine transfer was performed.
Rostyslav Bardovskyi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy