Results 41 to 50 of about 15,321 (234)

Noninsulin pharmacological management of type 1 diabetes mellitus

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
The injectable nature and other shortcomings of insulin have stimulated interest in studying the noninsulin pharmacological therapies to manage type 1 diabetes mellitus (T1DM).
Vishvas Garg
doaj   +1 more source

Biguanide iridium(III) complexes with potent antimicrobial activity [PDF]

open access: yes, 2018
We have synthesized novel organoiridium(III) antimicrobial complexes containing a chelated biguanide, including the antidiabetic drug metformin. These 16- and 18-electron complexes were characterized by NMR, ESI-MS, elemental analysis, and X-ray ...
Chen, Feng   +8 more
core   +2 more sources

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin [PDF]

open access: yes, 2018
Metformin use is associated with reduced cancer mortality, but how metformin impacts cancer outcomes is controversial. Although metformin can act on cells autonomously to inhibit tumor growth, the doses of metformin that inhibit proliferation in tissue ...
Bush, Lauren N.   +9 more
core   +1 more source

Quantitative determination of 0.05 % chlorhexidine solution by capillary electrophoresis

open access: yesZaporožskij Medicinskij Žurnal, 2019
The aim of the work was to estimate the quantitative content of 0.05 % chlorhexidine solution by capillary electrophoresis. Materials and methods.
A. M. Sampiiev   +3 more
doaj   +1 more source

The role of pharmacogenetics in the treatment of diabetes mellitus [PDF]

open access: yesJournal of Medical Biochemistry, 2014
Diabetes mellitus is a heterogeneous group of disorders in which particular disease phenotypes can be characterized by a specific etiology and/or pathogenesis of the disease, but in many cases its classification is greatly impeded due to significant ...
Topić Elizabeta
doaj  

LKB1 and AMPK and the cancer-metabolism link - ten years after [PDF]

open access: yes, 2013
The identification of a complex containing the tumor suppressor LKB1 as the critical upstream kinase required for the activation of AMP-activated protein kinase (AMPK) by metabolic stress was reported in an article in Journal of Biology in 2003.
A Decensi   +90 more
core   +3 more sources

Determination of Biguanide Groups in Polyhexamethylene Biguanide Hydrochloride by Titrimetric Methods

open access: yesAnalytical Sciences, 2003
The biguanide concentration of polyhexamethylene biguanide hydrochloride (PHMB-HCl) was measured by non-aqueous titration with HClO4, argentometric titration, the Kjeldhal method, and colloidal titration. The summation value of non-aqueous titration and argentometric titration corresponded to two titrable nitrogens in five nitrogens per one unit of ...
Toshiaki Hattori   +2 more
openaire   +3 more sources

Metformin: mechanistic and cardiovascular effects [PDF]

open access: yes, 2022
Metformin is a drug that has been used for the treatment of diabetes for 65 years. Research shows that metformin is a versatile drug that not only has beneficial effects on lowering blood sugar levels, but also has protective effects on cardiovascular ...
Top, Michel
core   +1 more source

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