Results 71 to 80 of about 9,884 (217)

Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study

Acta Pharmaceutica, 2018
Extensive in vitro studies have been conducted to evaluate the anticancer activity of oral hypoglycemic agents. Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media ...
Bardaweel Sanaa K., Alsalamat Husam A., Aleidi Shereen M., Bashatwah Rasha M.   +3 more
doaj   +1 more source

Surface-Modified Carboxylated Cellulose Nanofiber Hydrogels for Prolonged Release of Polyhexamethylene Biguanide Hydrochloride (PHMB) for Antimicrobial Applications [PDF]

, 2023
Pichapar O-chongpian, Tanpong Chaiwarit, Kittisak Jantanasakulwong, Pornchai Rachtanapun, Patnarin Worajittiphon, Nutthapong Kantrong, Pensak Jantrawut   +6 more
openalex   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Biguanides enhance antifungal activity against Candida glabrata

Virulence, 2018
Candida spp. are the fourth leading cause of nosocomial blood stream infections in North America. Candida glabrata is the second most frequently isolated species, and rapid development of antifungal resistance has made treatment a challenge.
Shuying Xu, Marianela Feliu, Allison K. Lord, Daniel P. Lukason, Paige E. Negoro, Nida S. Khan, Zeina Dagher, Michael B. Feldman, Jennifer L. Reedy, Samantha N. Steiger, Jenny M. Tam, Alexander A. Soukas, David B. Sykes, Michael K. Mansour   +13 more
doaj   +1 more source

Impact of Insulin, Biguanide and Sulfonylurea Treatment on hba1c in Diabetic Patients: An Interventional Study in Rajshahi, Bangladesh

, 2023
Md Saif Zaman, Parvez Hassan, SM Shahinul Islam, Md Anayet Ullah, Md. Golam Rabbani   +4 more
openalex   +2 more sources

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

Cancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa, N. D. Amal Wageesha, Sameera R. Samarakoon, Sagarika Ekanayake, H. M. Kasuni Akalanka   +4 more
wiley   +1 more source

Inhibitory and lethal effects of chlorhexidine and a polymeric biguanide on some strains of Providencia stuartii [PDF]

, 1987
Nashat A. Ismaeel, J. R. Furr, A.D. Russell   +2 more
openalex   +1 more source

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

Acta Ophthalmologica, Volume 104, Issue 1, Page 44-51, February 2026.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Anders Ivarsen   +5 more
wiley   +1 more source

Amlodipine and valsartan improving effect on the survival rate and deleterious pathological changes in streptozotocin-induced diabetic rats treated with metformin

Pharmaceutical and Biomedical Research, 2019
Diabetes mellitus (DM) and hypertension usually co-exist, and when this happens, the prognosis would be worse than each disease alone. Given this, we evaluated the possible effects of valsartan and amlodipine administration on metformin-treated diabetic ...
Israel Olapeju Bolanle, Eric Kelly Inanemo Omogbai, Enitome Bafor   +2 more
doaj  

Sita‐ and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross‐sectional study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Sören Dräger, Claudia Kauderer, Svenja Meyhöfer, Leonie Dräger, Jens U. Marquardt, Ralf J. Ludwig, Stephan Arndt, Katharina Boch, Katja Bieber   +8 more
wiley   +1 more source