Results 161 to 170 of about 39,146 (248)

Transcriptomic Analysis in the Liver of Two Rabbit Lines Divergently Selected for Intramuscular Fat Content

open access: yesAnimal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT The intramuscular fat (IMF) content is an important indicator of meat quality, affecting the sensory properties of meat. IMF is a complex trait with polygenic nature. This research aimed to identify differentially expressed (DE) genes and key transcription factors (TFs) associated with IMF deposition in the liver of two rabbit lines ...
Jesús Valdés‐Hernández   +4 more
wiley   +1 more source

Glycine: The missing link between carbohydrate and xenobiotic metabolism in the maturing human hepatocyte. [PDF]

open access: yesiScience
Pozo Garcia V   +6 more
europepmc   +1 more source

Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists

open access: yesArchiv der Pharmazie, Volume 359, Issue 6, June 2026.
Despite its long tradition in the treatment of liver‐related ailments, the precise mode of action of the milk thistle fruit extract remains vague. Here we identified liver X receptor as a molecular target of silymarin, a mixture of bioactive compounds from milk thistle extract, and its major flavanonol lignan components, which account for their anti ...
Nils C. Bandomir   +3 more
wiley   +1 more source

Harnessing Gut Microbiota to Enhance Immunotherapy in NSCLC: From Mechanisms to Translational Applications

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT The gut microbiome has emerged as a pivotal regulator of immunotherapy efficacy in non‐small cell lung cancer (NSCLC), with mounting evidence demonstrating that microbial‐immune crosstalk significantly influences therapeutic responses. Current research reveals that commensal bacteria modulate host immunity through complex metabolic and ...
Liming Zhu   +4 more
wiley   +1 more source

Ceramide‐mediated mitochondrial dysfunction in nonobese nonalcoholic fatty liver disease: A regulatory role for serine palmitoyltransferase subunit 2

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Serine palmitoyltransferase long chain base subunit 2 (Sptlc2) promotes ceramide‐associated mitochondrial dysfunction in nonobese nonalcoholic fatty liver disease (NAFLD). A dry‐fried soybean‐induced nonobese NAFLD model shows Sptlc2 upregulation, ceramide accumulation, and mitochondrial dysfunction.
Li‐Jun Xue   +4 more
wiley   +1 more source

Structural and Functional Properties of Ingredient Composition in Kenkey Preparation: A Review

open access: yesChemFoodChem, Volume 2, Issue 2, June 2026.
This review synthesizes three decades of research on kenkey, a fermented maize staple of West Africa. Examining the structural, functional, and nutritional properties that emerge from traditional fermentation and thermal processing, and identifying priorities for future research toward quality standardization and commercial development. ABSTRACT Kenkey,
Afia Sakyiwaa Amponsah
wiley   +1 more source

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