ABSTRACT The intramuscular fat (IMF) content is an important indicator of meat quality, affecting the sensory properties of meat. IMF is a complex trait with polygenic nature. This research aimed to identify differentially expressed (DE) genes and key transcription factors (TFs) associated with IMF deposition in the liver of two rabbit lines ...
Jesús Valdés‐Hernández +4 more
wiley +1 more source
From probiotic depletion to inflammatory cascade: multi-omics reveals the temporal progression of sleep deprivation-induced gut-liver axis disruption in mice. [PDF]
Dai MK +6 more
europepmc +1 more source
Glycine: The missing link between carbohydrate and xenobiotic metabolism in the maturing human hepatocyte. [PDF]
Pozo Garcia V +6 more
europepmc +1 more source
Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists
Despite its long tradition in the treatment of liver‐related ailments, the precise mode of action of the milk thistle fruit extract remains vague. Here we identified liver X receptor as a molecular target of silymarin, a mixture of bioactive compounds from milk thistle extract, and its major flavanonol lignan components, which account for their anti ...
Nils C. Bandomir +3 more
wiley +1 more source
Ureic clearance granule ameliorates chronic kidney disease by reshaping microbial dysbiosis via modulating bile acid metabolism. [PDF]
Liu LM +8 more
europepmc +1 more source
ABSTRACT The gut microbiome has emerged as a pivotal regulator of immunotherapy efficacy in non‐small cell lung cancer (NSCLC), with mounting evidence demonstrating that microbial‐immune crosstalk significantly influences therapeutic responses. Current research reveals that commensal bacteria modulate host immunity through complex metabolic and ...
Liming Zhu +4 more
wiley +1 more source
Integrated Metabolomic and Transcriptomic Analysis Reveals Host Response Mechanisms to Porcine Epidemic Diarrhea Virus Infection in Pigs. [PDF]
Zhou Y +7 more
europepmc +1 more source
Serine palmitoyltransferase long chain base subunit 2 (Sptlc2) promotes ceramide‐associated mitochondrial dysfunction in nonobese nonalcoholic fatty liver disease (NAFLD). A dry‐fried soybean‐induced nonobese NAFLD model shows Sptlc2 upregulation, ceramide accumulation, and mitochondrial dysfunction.
Li‐Jun Xue +4 more
wiley +1 more source
Integrative multi‑omics analysis of lipid metabolism during the growth and development of Qiandongnan Xiaoxiang chickens based on the gut‑muscle axis. [PDF]
Xie Y +7 more
europepmc +1 more source
Structural and Functional Properties of Ingredient Composition in Kenkey Preparation: A Review
This review synthesizes three decades of research on kenkey, a fermented maize staple of West Africa. Examining the structural, functional, and nutritional properties that emerge from traditional fermentation and thermal processing, and identifying priorities for future research toward quality standardization and commercial development. ABSTRACT Kenkey,
Afia Sakyiwaa Amponsah
wiley +1 more source

