Results 251 to 260 of about 3,456,901 (302)
Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies. [PDF]
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Annual Review of Biochemistry, 1975
INTRODUCTION 233 FORMATION OF BILE ACIDS 234 5fl Bile Acids 234 5~ Bile Acids 236 7c~ Hydroxylation of Cholesterol 237 12o~ Hydroxylation 238 26 Hydroxylation 238 Oxidation of 5fl-Chole~tane-3c~,7~t,12~,26-tetrol 239 METABOLISM OF BILE ACIDS 239 Conju,qation with Glycine and Taurine 240 Esterification with Sulfute and Glucuronic ...
H, Danielsson, J, Sjövall
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INTRODUCTION 233 FORMATION OF BILE ACIDS 234 5fl Bile Acids 234 5~ Bile Acids 236 7c~ Hydroxylation of Cholesterol 237 12o~ Hydroxylation 238 26 Hydroxylation 238 Oxidation of 5fl-Chole~tane-3c~,7~t,12~,26-tetrol 239 METABOLISM OF BILE ACIDS 239 Conju,qation with Glycine and Taurine 240 Esterification with Sulfute and Glucuronic ...
H, Danielsson, J, Sjövall
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Oxysterols in bile acid metabolism
Clinica Chimica Acta, 2011Increasing body of evidence is available indicating that oxysterols are more much than intermediates of metabolic pathways. Oxysterols play a role in the regulation of cholesterol synthesis, transport and efflux. A scavenger effect of cholesterol 27-hydroxylase on elevated serum cholesterol levels is well demonstrated.
Crosignani, A +3 more
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Bile acids and the metabolic syndrome
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2019Bile acids have important roles in the regulation of lipid, glucose and energy metabolism. Metabolic diseases linked to obesity, including type 2 diabetes mellitus and non-alcoholic fatty liver disease, are associated with dysregulation of bile acid homeostasis.
Emma Rose McGlone, Stephen R Bloom
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Bile acid metabolism and fiber
The American Journal of Clinical Nutrition, 1978Studies in experimental animals and in humans have shown a definite interaction of dietary fiber with bile acid metabolism. In experimental animals, some types of fiber have been shown to increase bile acid excretion as well as increase pool size and turnover of bile acids.
J A, Story, D, Kritchevsky
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Species differences in bile acids II. Bile acid metabolism
Journal of Applied Toxicology, 2018AbstractOne of the mechanisms of drug‐induced liver injury (DILI) involves alterations in bile acid (BA) homeostasis and elimination, which encompass several metabolic pathways including hydroxylation, amidation, sulfation, glucuronidation and glutathione conjugation.
Rhishikesh Thakare +4 more
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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Physiological Reviews, 2009The incidence of the metabolic syndrome has taken epidemic proportions in the past decades, contributing to an increased risk of cardiovascular disease and diabetes. The metabolic syndrome can be defined as a cluster of cardiovascular disease risk factors including visceral obesity, insulin resistance, dyslipidemia, increased blood pressure, and ...
Philippe, Lefebvre +4 more
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Bile Acid Metabolism and Signaling
Comprehensive Physiology, 2013Abstract Bile acids are important physiological agents for intestinal nutrient absorption and biliary secretion of lipids, toxic metabolites, and xenobiotics. Bile acids also are signaling molecules and metabolic regulators that activate nuclear receptors and G protein‐coupled receptor (GPCR) signaling to regulate
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Bile-acid metabolism and the liver
Clinical Biochemistry, 1976Primary bile acids are exclusively synthesize, and all bile acids are conjugated, in the liver. When hepatic function is altered by disease, not surprisingly the bile-acid metabolism reflects this change. 1. In chronic liver disorders the glycine: taurine ratio of serum and bile is reduced. 2.
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Bile acids and their receptors in metabolic disorders
Progress in Lipid Research, 2021Bile acids are a large family of atypical steroids which exert their functions by binding to a family of ubiquitous cell membrane and nuclear receptors. There are two main bile acid activated receptors, FXR and GPBAR1, that are exclusively activated by bile acids, while other receptors CAR, LXRs, PXR, RORγT, S1PR2and VDR are activated by bile acids in ...
Fiorucci, Stefano +4 more
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