Results 261 to 270 of about 3,456,901 (302)
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Bile acid metabolism and circadian rhythms
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2020Circadian rhythms are biological systems that synchronize cellular circadian oscillators and regulate nutrient absorption and utilization. Bile acids are important modulators that facilitate nutrient absorption and regulate energy metabolism. Bile acid metabolism and circadian rhythms are related to metabolic diseases, and their intersections have not ...
Yunxia Yang, Jianfa Zhang
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Inborn errors of bile acid metabolism
Journal of Inherited Metabolic Disease, 1991SummaryCholesterol is converted to cholic acid and chenodeoxycholic acid by a series of reactions involving modifications to the steroid nucleus and oxidation of the side chain. These reactions can be affected by a number of inborn errors of metabolism. When this happens unusual bile acids or bile alcohols are synthesized; these can be identified using
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Biochemical Medicine and Metabolic Biology, 1986
The objective of this study was to examine the effect of glucocorticoid treatment in early neonatal life on plasma cholesterol and hepatic cholesterol 7 alpha-hydroxylase (CH-7A), the rate-limiting enzyme of bile acid biosynthesis from cholesterol, measured at weaning (Postnatal Day 20).
A S, Hassan, J J, Hackley, C J, Fischer
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The objective of this study was to examine the effect of glucocorticoid treatment in early neonatal life on plasma cholesterol and hepatic cholesterol 7 alpha-hydroxylase (CH-7A), the rate-limiting enzyme of bile acid biosynthesis from cholesterol, measured at weaning (Postnatal Day 20).
A S, Hassan, J J, Hackley, C J, Fischer
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Bile acid sequestrants: Mechanisms of action on bile acid and cholesterol metabolism
European Journal of Clinical Pharmacology, 1991Interruption of the enterohepatic circulation of bile acids by cholestyramine or colestipol influences the hepatic metabolism of cholesterol in many ways. The synthesis of bile acids is increased, as reflected by a several-fold increase in the activity of the cholesterol 7 alpha hydroxylase, the rate-determining enzyme in bile acid synthesis.
K, Einarsson +6 more
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Bile acids and lipoprotein metabolism
Current Opinion in Lipidology, 1999Based on an improved molecular understanding of how bile acid metabolism is regulated, an exciting period of research developments can be expected. By new ways of stimulating cholesterol breakdown to bile acids, novel therapeutic principles can be forseen which will further improve our potential for treating and preventing atherosclerosis.
B, Angelin, M, Eriksson, M, Rudling
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Unique bile acid metabolism in centenarians
Nature Reviews Microbiology, 2021A study of centenarians from Japan shows that they have unique bile-metabolizing bacteria in their gut microbiota.
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2017
Bile acids are biosynthesized from cholesterol in the liver. Cholic acid (CA), chenodeoxycholic acid (CDCA), and deoxycholic acid (DCA) are major bile acids in humans. Neutral (classical) pathway is the major pathway of the bile acid biosynthesis in adult humans, which starts from 7ɑ-hydroxylation of cholesterol, catalyzed by cholesterol 7ɑ-hydroxylase
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Bile acids are biosynthesized from cholesterol in the liver. Cholic acid (CA), chenodeoxycholic acid (CDCA), and deoxycholic acid (DCA) are major bile acids in humans. Neutral (classical) pathway is the major pathway of the bile acid biosynthesis in adult humans, which starts from 7ɑ-hydroxylation of cholesterol, catalyzed by cholesterol 7ɑ-hydroxylase
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Bile acid metabolism in analbuminemic rats
Lipids, 1998AbstractThe bile acid concentrations in the serum, liver, bile, intestines, and feces of 3‐ and 19‐mon‐old male and female Nagase analbuminemic (NA) rats were compared with those in Sprague‐Dawley (SD) rats. There was no significant difference in the bile acid levels between NA and SD rats.
A, Kambe +4 more
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Chemistry and Metabolism of Bile Alcohols and Higher Bile Acids
1968Publisher Summary This chapter discusses the chemistry and metabolism of bile alcohols and higher bile acids. The bile acids, occurring in the bile of mammals, birds, some snakes, and most bony fish are all mono-, di-or trihydroxy derivatives of the cholanoic acid.
T, Hoshita, T, Kazuno
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1986
Transport and metabolism of bile acids by the liver have been the subject of several recent reviews.1–3 In this chapter, however, the problem is analyzed in a different context. An attempt is made to integrate the development of these functions in the fetal and newborn liver with the transport and metabolic regulation of bile acids observed in the ...
Jorge J. Gumucio +2 more
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Transport and metabolism of bile acids by the liver have been the subject of several recent reviews.1–3 In this chapter, however, the problem is analyzed in a different context. An attempt is made to integrate the development of these functions in the fetal and newborn liver with the transport and metabolic regulation of bile acids observed in the ...
Jorge J. Gumucio +2 more
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