Results 11 to 20 of about 238,773 (337)
Bile acids. LXVII. The major bile acids of Varanus monitor
Journal of Lipid Research, 1982 The major bile acids of gall bladder bile of Varanus monitor have been separated by thin-layer chromatography and shown to be derivatives of taurine.
S S Ali, E Stephenson, W H Elliott
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Annals of Hepatology, 2017 The primary bile acids (BAs) are synthetized from colesterol in the liver, conjugated to glycine or taurine to increase their solubility, secreted into bile, concentrated in the gallbladder during fasting, and expelled in the intestine in response to dietary fat, as well as bio-transformed in the colon to the secondary BAs by the gut microbiota ...
Agostino Di Ciaula +6 more
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Journal of Lipid Research, 2009 In liver and intestine, transporters play a critical role in maintaining the enterohepatic circulation and bile acid homeostasis. Over the past two decades, there has been significant progress toward identifying the individual membrane transporters and unraveling their complex regulation.
Tian Lan, Paul A. Dawson, Anuradha Rao
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Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice [PDF]
Journal of Lipid Research, 2010 An improved ultra performance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS) method was established for the simultaneous analysis of various bile acids (BA) and applied to investigate liver BA content in C57BL/6 mice fed 1% cholic acid (CA), 0.3% deoxycholic acid (DCA), 0.3% chenodeoxycholic acid (CDCA), 0.3% lithocholic acid (LCA), 3 ...
Youcai Zhang, Curtis D. Klaassen
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The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease. [PDF]
, 2018 BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia.
Bao, X +7 more
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Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation. [PDF]
, 2017 Fructus Gardenia (FG), containing the major active constituent Geniposide, is widely used in China for medicinal purposes. Currently, clinical reports of FG toxicity have not been published, however, animal studies have shown FG or Geniposide can cause ...
Feng, Xiaoyi +17 more
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Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells [PDF]
, 2009 In patients with bile acid malabsorption, high concentrations of bile acids enter the colon and stimulate Cl− and fluid secretion, thereby causing diarrhoea. However, deoxycholic acid (DCA), the predominant colonic bile acid, is normally present at lower
Alan F. Hofmann +45 more
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Bile Acids Conjugation in Human Bile Is Not Random: New Insights from 1H-NMR Spectroscopy at 800 MHz [PDF]
, 2009 Bile acids constitute a group of structurally closely related molecules and represent the most abundant constituents of human bile. Investigations of bile acids have garnered increased interest owing to their recently discovered additional biological ...
Cooper, Amanda +4 more
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Profiling of Urinary Glucuronidated Bile Acids across Age Groups
Metabolites, 2022 We investigated the age-dependent changes in urinary excretion of glucuronidated bile acids at the C-3 position. Bile acid 3-glucuronides accounted for 0.5% of urinary bile acids in neonates, and the proportion of bile acid 3-glucuronides plateaued at 1 ...
Yamato Muto +6 more
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