Efficacy of a Tibia Counter Rotator System for the Treatment of Internal Tibial Torsion in Children
Children, 2022 Internal tibial torsion is more common in the Asian population than in Western populations. Generally, surgery should be considered for the treatment of severe internal tibial torsion. As an alternative approach, the usefulness of a tibia counter rotator
Sungmi Kim +4 more
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Bile acids as inflammatory mediators and modulators of intestinal permeability
Frontiers in Immunology, 2022 Bile acids are critical for the digestion and absorption of lipids and fat-soluble vitamins; however, evidence continues to emerge supporting additional roles for bile acids as signaling molecules. After they are synthesized from cholesterol in the liver,
Nathan Calzadilla +9 more
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Bile acid patterns in commercially available oxgall powders used for the evaluation of the bile tolerance ability of potential probiotics. [PDF]
PLoS ONE, 2018 This study aimed to analyze the bile acid patterns in commercially available oxgall powders used for evaluation of the bile tolerance ability of probiotic bacteria.
Peng-Li Hu +3 more
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A Recent Ten-Year Perspective: Bile Acid Metabolism and Signaling
Molecules, 2022 Bile acids are important physiological agents required for the absorption, distribution, metabolism, and excretion of nutrients. In addition, bile acids act as sensors of intestinal contents, which are determined by the change in the spectrum of bile ...
Yulia Shulpekova +13 more
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Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). [PDF]
PLoS ONE, 2016 Besides their role in intestinal resorption of lipids, bile acids are regarded as endocrine and metabolic signaling molecules. The detailed profile of bile acid species in peripheral blood after an oral lipid tolerance test (OLTT) is unknown.We ...
Andreas Schmid +4 more
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Bile Acids: Physiological Activity and Perspectives of Using in Clinical and Laboratory Diagnostics
Molecules, 2022 Bile acids play a significant role in the digestion of nutrients. In addition, bile acids perform a signaling function through their blood-circulating fraction. They regulate the activity of nuclear and membrane receptors, located in many tissues.
Yaroslav Shansky, Julia Bespyatykh
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Biosynthesis and biotransformation of bile acids [PDF]
Hospital Pharmacology, 2017 Bile acids are steroidal compounds, which contain 24 carbon atoms. They can be classified into two major groups: primary and secondary. The most abundant bile acids: The primary bile acids include cholic acid and chenodeoxycholic acid, while the major ...
Šarenac Tanja M., Mikov Momir M.
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Cholestasis impairs gut microbiota development and bile salt hydrolase activity in preterm neonates
Gut Microbes, 2023 Cholestasis refers to impaired bile flow from the liver to the intestine. In neonates, cholestasis causes poor growth and may progress to liver failure and death.
Lauren E. Lynch +7 more
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Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]
arXiv, 2023 Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv