Results 1 to 10 of about 26,722 (309)

Effect of Digestion on Ursolic Acid Self-Stabilized Water-in-Oil Emulsion: Role of Bile Salts [PDF]

Foods, 2023
Exploring the effect of bile salts on the properties of emulsion carriers containing hydrophobic bioactive compounds is particularly critical to understanding the stability and bioavailability of these hydrophobic bioactive compounds in the digestive ...
Yumeng Yan, Yugang Liu, Chaoxi Zeng, Huiping Xia   +3 more
doaj   +2 more sources

Role of Bile Acids and Bile Salts in Acute Pancreatitis

Pancreas, 2020
Abstract Acute pancreatitis (AP) is one of the most common gastroenterological disorders leading to hospitalization. It has long been debated whether biliary AP, about 30% to 50% of all cases, is induced by bile acids (BAs) when they reach the pancreas via reflux or via the systemic blood circulation.
Quang Trung Tran, Van Huy Tran, Matthias Sendler, Julia Doller, Mats L. Wiese, Robert Bolsmann, Anika Wilden, Juliane Glaubitz, Jana Marielle Modenbach, Franziska G. Thiel, Laura L. de Freitas Chama, Frank Ulrich Weiß, Markus M. Lerch, Ali A. Aghdassi   +13 more
openalex   +4 more sources

Bile Acids and Bile Salts: Ionization and Solubility Properties [PDF]

Hepatology, 1984
The number, position and orientation of nuclear OH substituents profoundly influence the equilibrium solubilities of undissociated bile acids in water. Estimates from several studies range from 5 × 10″8 for lithocholic acid to 1.6 × 10−3 Af for ursocholic acid at 37°C.
Martin C. Carey
openalex   +3 more sources

Antimicrobial and healing efficacy of bile salts with insights into cytotoxic activity [PDF]

Scientific Reports
Bile salts play crucial roles in lipid digestion and metabolism, with emerging evidence suggesting their involvement in cell signaling, wound healing, and potential antimicrobial activities.
Aisha M. H. Al-Rajhi, Sulaiman A. Alsalamah, Abdullah M. Almotayri, Nourah M. Almimoni, Rabab A. Hegazy, Husam Qanash, Tarek M. Abdelghany   +6 more
doaj   +2 more sources

Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling [PDF]

Nature Communications, 2016
AbstractAutotaxin (ATX) generates the lipid mediator lysophosphatidic acid (LPA). ATX-LPA signalling is involved in multiple biological and pathophysiological processes, including vasculogenesis, fibrosis, cholestatic pruritus and tumour progression. ATX has a tripartite active site, combining a hydrophilic groove, a hydrophobic lipid-binding pocket ...
Willem‐Jan Keune, Jens Hausmann, Ruth Bolier, Dagmar Tolenaars, Andreas E. Kremer, Tatjana Heidebrecht, Robbie P. Joosten, Manjula Sunkara, Andrew J. Morris, Elisa Matas-Rico, Wouter H. Moolenaar, Ronald P.J. Oude Elferink, Anastassis Perrakis   +12 more
openalex   +7 more sources

Solubility of calcium salts of unconjugated and conjugated natural bile acids.

Journal of Lipid Research, 1992
The approximate solubility products of the calcium salts of ten unconjugated bile acids and several taurine conjugated bile acids were determined. The formation of micelles, gels, and/or precipitates in relation to Ca2+,Na+, and bile salt concentration ...
JJ Gu, AF Hofmann, HT Ton-Nu, CD Schteingart, KJ Mysels   +4 more
doaj   +2 more sources

Bile Salt Composition and Distribution of the D-Cysteinolic Acid Conjugated Bile Salts in Fish

Fisheries science, 1996
Takanobu Goto, Takuji Ui, Mizuho Une, Taiju Kuramoto, Kenji Kihira, Takahiko Hoshita   +5 more
openalex   +3 more sources

Antiviral and virucidal activities against SARS-CoV-2 and antibacterial properties of bile acids and their salts with naturally occurring organic cations of l-carnitine, creatinine, and choline. [PDF]

RSC Adv
Varongkriengkrai C, Chutiwitoonchai N, Leerach N, Sureram S, Pooprasert T, Aree T, Khoomrung S, Mahidol C, Ruchirawat S, Kittakoop P.   +9 more
europepmc   +3 more sources

Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

Journal of Lipid Research, 2023
N-acyl taurines (NATs) are bioactive lipids with emerging roles in glucose homeostasis and lipid metabolism. The acyl chains of hepatic and biliary NATs are enriched in polyunsaturated fatty acids (PUFAs).
Samuel A.J. Trammell, Luke F. Gamon, Kamil Gotfryd, Katja Thorøe Michler, Bandar D. Alrehaili, Iben Rix, Filip K. Knop, Pontus Gourdon, Yoon-Kwang Lee, Michael J. Davies, Matthew P. Gillum, Trisha J. Grevengoed   +11 more
doaj   +1 more source

Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts [PDF]

Journal of Biological Chemistry, 2019
The fish olfactory receptor ORA family is orthologous to the mammalian vomeronasal receptors type 1. It consists of six highly conserved chemosensory receptors expected to be essential for survival and communication. We deorphanized the zebrafish ORA family in a heterologous cell system. The six receptors responded specifically to lithocholic acid (LCA)
Xiaojing Cong, Qian Zheng, Wenwen Ren, Jean-Baptiste Chéron, Sébastien Fiorucci, Tieqiao Wen, Chunbo Zhang, Hongmeng Yu, Jérôme Golebiowski, Yiqun Yu   +9 more
openaire   +3 more sources