Results 11 to 20 of about 26,722 (309)

A new insight into the physiological role of bile salt hydrolase among intestinal bacteria from the genus Bifidobacterium. [PDF]

open access: yesPLoS ONE, 2014
This study analyzes the occurrence of bile salt hydrolase in fourteen strains belonging to the genus Bifidobacterium. Deconjugation activity was detected using a plate test, two-step enzymatic reaction and activity staining on a native polyacrylamide gel.
Piotr Jarocki   +3 more
doaj   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 2. Regulation of bile acid synthesis by enterohepatic circulation of bile acids.

open access: yesJournal of Lipid Research, 1984
Isotope dilution within bile acid pools and radiochemical assessment of cholesterol oxidation to bile acids were methods used to measure short-term feedback regulation of bile acid synthesis in baboons with controlled enterohepatic circulations ...
R N Redinger
doaj   +1 more source

Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2+ ions.

open access: yesJournal of Lipid Research, 1992
The principles governing the in vitro solubility of the common natural conjugated and unconjugated bile acids and salts in relation to pH, micelle formation, and Ca2+ concentration are considered from a theoretical standpoint and then correlated first ...
AF Hofmann, KJ Mysels
doaj   +1 more source

Comprehensive evaluation of the bactericidal activities of free bile acids in the large intestine of humans and rodents

open access: yesJournal of Lipid Research, 2017
In addition to functioning as detergents that aid digestion of dietary lipids in the intestine, some bile acids have been shown to exhibit antimicrobial activity.
Masamichi Watanabe   +2 more
doaj   +1 more source

Brucella abortus choloylglycine hydrolase affects cell envelope composition and host cell internalization. [PDF]

open access: yesPLoS ONE, 2011
Choloylglycine hydrolase (CGH, E.C. 3.5.1.24) is a conjugated bile salt hydrolase that catalyses the hydrolysis of the amide bond in conjugated bile acids.
María Inés Marchesini   +6 more
doaj   +1 more source

Bile salts of vertebrates: structural variation and possible evolutionary significance[S]

open access: yesJournal of Lipid Research, 2010
Biliary bile salt composition of 677 vertebrate species (103 fish, 130 reptiles, 271 birds, 173 mammals) was determined. Bile salts were of three types: C27 bile alcohols, C27 bile acids, or C24 bile acids, with default hydroxylation at C-3 and C-7.
Alan F. Hofmann   +2 more
doaj   +1 more source

Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions.

open access: yesJournal of Lipid Research, 1989
This paper describes the derivation of a bile salt monomeric hydrophobicity index that quantitatively defines the composite hydrophilic-hydrophobic balance of a mixture of bile salts.
D M Heuman
doaj   +1 more source

A fast and simple ion-pair high performance liquid chromatography method for analysis of primary bile salts in in vitro digested bean samples

open access: yesMethodsX, 2021
Bile salts (BS) play a key role in cholesterol and lipid metabolism as well as in many other key metabolic pathways. High performance liquid chromatography (HPLC) is the most common technique used to analyze BS in diverse type of samples.
Tiantian Lin   +2 more
doaj   +1 more source

Recent advances in nonalcoholic fatty liver disease metabolomics [PDF]

open access: yesClinical and Molecular Hepatology, 2021
The clinical phenotypes of nonalcoholic fatty liver disease (NAFLD) encompass from simple steatosis to nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis or cirrhosis. Liver biopsy has been the standard to diagnose NASH.
Hwi Young Kim
doaj   +1 more source

Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat.

open access: yesJournal of Lipid Research, 1989
Hepatic bile acid synthesis is thought to be under negative feedback control by bile salts in the enterohepatic circulation, acting at the level of cholesterol 7 alpha-hydroxylase (C7 alpha H), the initial and rate-limiting step in the bile acid ...
D M Heuman, P B Hylemon, Z R Vlahcevic
doaj   +1 more source

Home - About - Disclaimer - Privacy