Results 21 to 30 of about 57,138 (354)

Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions.

Journal of Lipid Research, 1989
This paper describes the derivation of a bile salt monomeric hydrophobicity index that quantitatively defines the composite hydrophilic-hydrophobic balance of a mixture of bile salts.
D M Heuman
doaj   +1 more source

Recent advances in nonalcoholic fatty liver disease metabolomics [PDF]

Clinical and Molecular Hepatology, 2021
The clinical phenotypes of nonalcoholic fatty liver disease (NAFLD) encompass from simple steatosis to nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis or cirrhosis. Liver biopsy has been the standard to diagnose NASH.
Hwi Young Kim
doaj   +1 more source

A fast and simple ion-pair high performance liquid chromatography method for analysis of primary bile salts in in vitro digested bean samples

MethodsX, 2021
Bile salts (BS) play a key role in cholesterol and lipid metabolism as well as in many other key metabolic pathways. High performance liquid chromatography (HPLC) is the most common technique used to analyze BS in diverse type of samples.
Tiantian Lin, Sean O'Keefe, Cristina Fernández-Fraguas   +2 more
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Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat.

Journal of Lipid Research, 1989
Hepatic bile acid synthesis is thought to be under negative feedback control by bile salts in the enterohepatic circulation, acting at the level of cholesterol 7 alpha-hydroxylase (C7 alpha H), the initial and rate-limiting step in the bile acid ...
D M Heuman, P B Hylemon, Z R Vlahcevic
doaj   +1 more source

New Kids on the Block: Bile Salt Conjugates of Microbial Origin

Metabolites, 2022
Biotransformation of host bile salts by gut microbes results in generation of secondary bile salt species that have biological and physicochemical properties that are distinct from the parent compounds.
Ümran Ay, Martin Leníček, Arno Classen, Steven W. M. Olde Damink, Carsten Bolm, Frank G. Schaap   +5 more
doaj   +1 more source

Wormlike reverse micelles in lecithin/bile salt/water mixtures in oil [PDF]

, 2017
Knowing the ability of water and bile salts to promote the reverse wormlike micelle growth in lecithin/water or lecithin/bile salt mixtures in oil, this work was aimed at elucidating the association properties of the three solutes lecithin, water and the
Cautela, Jacopo, Galantini, Luciano, Giustini, Mauro, Palazzo, Gerardo, Pavel, Nicolae Viorel   +4 more
core   +1 more source

Bile resistance mechanisms in Lactobacillus and Bifidobacterium

Frontiers in Microbiology, 2013
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Most of the probiotic bacteria currently available in the market belong to the genera Lactobacillus and Bifidobacterium, and specific ...
Lorena eRuiz, Abelardo eMargolles, Borja eSánchez   +2 more
doaj   +1 more source

Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties[S]

Journal of Lipid Research, 2015
Cytotoxic bile acids, such as deoxycholic acid (DCA), are responsible for hepatocyte cell death during intrahepatic cholestasis. The mechanisms responsible for this effect are unclear, and recent studies conflict, pointing to either a modulation of ...
Tânia Sousa, Rui E. Castro, Sandra N. Pinto, Ana Coutinho, Susana D. Lucas, Rui Moreira, Cecília M.P. Rodrigues, Manuel Prieto, Fábio Fernandes   +8 more
doaj   +1 more source

Preliminary evaluation of probiotic properties of Lactobacillus strains isolated from Sardinian dairy products [PDF]

, 2014
Twenty-three Lactobacillus strains of dairy origin were evaluated for some functional properties relevant to their use as probiotics. A preliminary subtractive screening based on the abilities to inhibit the growth of microbial pathogens and hydrolyze ...
Conti S, Cosentino S, Deiana M, Deplano M, Fadda ME, Melis MP, Pisano MB, Viale S   +7 more
core   +1 more source

Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions

mSphere, 2018
Clostridium difficile is a Gram-positive obligate anaerobe that forms spores in order to survive for long periods in the unfavorable environment outside a host. C. difficile is the leading cause of nosocomial infectious diarrhea worldwide. C.
Travis J. Kochan, Michelle S. Shoshiev, Jessica L. Hastie, Madeline J. Somers, Yael M. Plotnick, Daniela F. Gutierrez-Munoz, Elissa D. Foss, Alyxandria M. Schubert, Ashley D. Smith, Sally K. Zimmerman, Paul E. Carlson, Philip C. Hanna   +11 more
doaj   +1 more source