Results 21 to 30 of about 29,638 (318)

The effect of bile acids on the growth and global gene expression profiles in Akkermansia muciniphila

Applied Microbiology and Biotechnology, 2020
Akkermansia muciniphila is a prominent member of the gut microbiota and the organism gets exposed to bile acids within this niche. Several gut bacteria have bile response genes to metabolize bile acids or an ability to change their membrane structure to ...
T. Hagi, Sharon Y. Geerlings, Bart Nijsse, C. Belzer   +3 more
semanticscholar   +1 more source

Impact of bile salts and a medium chain fatty acid on the physical properties of self-emulsifying drug delivery systems

Drug Development and Industrial Pharmacy, 2020
The aim of this study was the evaluation of the influence of bile salts and fatty acids, important components of intestinal fluids, on physical characteristics of self-emulsifying drug delivery systems (SEDDS) such as size, polydispersity (PDI), zeta ...
Noemi Lupo, Christian Steinbring, J. Friedl, Bao Le-Vinh, A. Bernkop‐Schnürch   +4 more
semanticscholar   +1 more source

Bile resistance mechanisms in Lactobacillus and Bifidobacterium

Frontiers in Microbiology, 2013
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Most of the probiotic bacteria currently available in the market belong to the genera Lactobacillus and Bifidobacterium, and specific ...
Lorena eRuiz, Abelardo eMargolles, Borja eSánchez   +2 more
doaj   +1 more source

Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

Journal of Lipid Research, 2023
N-acyl taurines (NATs) are bioactive lipids with emerging roles in glucose homeostasis and lipid metabolism. The acyl chains of hepatic and biliary NATs are enriched in polyunsaturated fatty acids (PUFAs).
Samuel A.J. Trammell, Luke F. Gamon, Kamil Gotfryd, Katja Thorøe Michler, Bandar D. Alrehaili, Iben Rix, Filip K. Knop, Pontus Gourdon, Yoon-Kwang Lee, Michael J. Davies, Matthew P. Gillum, Trisha J. Grevengoed   +11 more
doaj  

Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions

mSphere, 2018
Clostridium difficile is a Gram-positive obligate anaerobe that forms spores in order to survive for long periods in the unfavorable environment outside a host. C. difficile is the leading cause of nosocomial infectious diarrhea worldwide. C.
Travis J. Kochan, Michelle S. Shoshiev, Jessica L. Hastie, Madeline J. Somers, Yael M. Plotnick, Daniela F. Gutierrez-Munoz, Elissa D. Foss, Alyxandria M. Schubert, Ashley D. Smith, Sally K. Zimmerman, Paul E. Carlson, Philip C. Hanna   +11 more
doaj   +1 more source

Bile Salt Hydrolase-Competent Probiotics in the Management of IBD: Unlocking the “Bile Acid Code”

Nutrients, 2022
Bile acid (BA) species and the gut microbiota (GM) contribute to intestinal mucosa homeostasis. BAs shape the GM and, conversely, intestinal bacteria with bile salt hydrolase (BSH) activity modulate the BA pool composition. The mutual interaction between BAs and intestinal microorganisms also influences mucosal barrier integrity, which is important for
Raffaella Maria Gadaleta, Marica Cariello, Lucilla Crudele, Antonio Moschetta   +3 more
openaire   +3 more sources

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

npj Biofilms and Microbiomes, 2022
The Clostridioides difficile pathogen is responsible for nosocomial infections. Germination is an essential step for the establishment of C. difficile infection (CDI) because toxins that are secreted by vegetative cells are responsible for the symptoms ...
Andrea Martinez Aguirre, Adegoke Oyeleye Adegbite, Joseph A. Sorg   +2 more
doaj   +1 more source

Dietary Bile Salt Types Influence the Composition of Biliary Bile Acids and Gut Microbiota in Grass Carp

Frontiers in Microbiology, 2018
Lipid metabolism can influence host’s health. There is increasing evidence for interplay between two key regulating factors in lipid metabolism: bile acids (BAs) and gut microbiota.
Fan Xiong, S. Wu, Jing Zhang, Ivan Jakovlić, Wenxiang Li, H. Zou, Ming Li, Gui‐tang Wang   +7 more
semanticscholar   +1 more source

Bile Composition - which Components Can Have Clinical Significance? A Review of the Literature.

Journal of Gastrointestinal and Liver Diseases, 2023
Over the years, scientific research concerning the qualitative analysis of bile and its use in diagnostics and treatment, have been very limited. Due to unsatisfactory results of detection, inter alia, cholangiocarcinoma or gallbladder carcinoma, and the
Pawel Podgorski, A. Przybyłkowski, P. Nehring   +2 more
semanticscholar   +1 more source

Comparison of Biochemical Characteristics of Lactobacilli Isolates from Food and Bovine Rumen Sources under Low pH and Bile Salt Stress Conditions

Chemical Engineering Transactions, 2017
In this study, two lactobacilli isolates, from dairy food and bovine rumen, were used to investigate the differences in their biochemical characteristics when exposed to low pH and bile salt stress conditions.
N.M. Jose, C.R. Bunt, M.A. Hussain
doaj   +1 more source