Results 21 to 30 of about 26,722 (309)

Bile resistance mechanisms in Lactobacillus and Bifidobacterium

Frontiers in Microbiology, 2013
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Most of the probiotic bacteria currently available in the market belong to the genera Lactobacillus and Bifidobacterium, and specific ...
Lorena eRuiz, Abelardo eMargolles, Borja eSánchez   +2 more
doaj   +1 more source

New Kids on the Block: Bile Salt Conjugates of Microbial Origin

Metabolites, 2022
Biotransformation of host bile salts by gut microbes results in generation of secondary bile salt species that have biological and physicochemical properties that are distinct from the parent compounds.
Ümran Ay, Martin Leníček, Arno Classen, Steven W. M. Olde Damink, Carsten Bolm, Frank G. Schaap   +5 more
doaj   +1 more source

Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties[S]

Journal of Lipid Research, 2015
Cytotoxic bile acids, such as deoxycholic acid (DCA), are responsible for hepatocyte cell death during intrahepatic cholestasis. The mechanisms responsible for this effect are unclear, and recent studies conflict, pointing to either a modulation of ...
Tânia Sousa, Rui E. Castro, Sandra N. Pinto, Ana Coutinho, Susana D. Lucas, Rui Moreira, Cecília M.P. Rodrigues, Manuel Prieto, Fábio Fernandes   +8 more
doaj   +1 more source

Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions

mSphere, 2018
Clostridium difficile is a Gram-positive obligate anaerobe that forms spores in order to survive for long periods in the unfavorable environment outside a host. C. difficile is the leading cause of nosocomial infectious diarrhea worldwide. C.
Travis J. Kochan, Michelle S. Shoshiev, Jessica L. Hastie, Madeline J. Somers, Yael M. Plotnick, Daniela F. Gutierrez-Munoz, Elissa D. Foss, Alyxandria M. Schubert, Ashley D. Smith, Sally K. Zimmerman, Paul E. Carlson, Philip C. Hanna   +11 more
doaj   +1 more source

Method for removal of surface-active impurities and calcium from conjugated bile salt preparations: comparison with silicic acid chromatography.

Journal of Lipid Research, 1995
Some commercial preparations of common natural conjugated bile salts contain impurities (e.g., amines, lipids, and calcium) that are likely to affect their physicochemical properties. A method was developed for purifying commercial preparations of sodium
S. Del Vecchio, J.D. Ostrow, P. Mukerjee, H.T. Ton-Nu, C.D. Schteingart, A.F. Hofmann, C. Cerrè, A. Roda   +7 more
doaj   +1 more source

A phylogenetic survey of biliary lipids in vertebrates1,

Journal of Lipid Research, 2005
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta, Fang Xu, Lee R. Hagey, Gerard P. van Berge-Henegouwen, Karel J. van Erpecum, Jos F. Brouwers, Jonathan C. Cohen, Molly Bierman, Helen H. Hobbs, Joseph H. Steinbach, Alan F. Hofmann   +10 more
doaj   +1 more source

A high-throughput LC-MS/MS method for the measurement of the bile acid/salt content in microbiome-derived sample sets

MethodsX, 2020
Due to the physicochemical properties of bile acids/salts (i.e., hydrophobic and ionizable), the application of reverse-phase liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based methods are ideally suited for the measurement of these ...
Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Jennifer M. Auchtung, Anthony M. Haag   +4 more
doaj   +1 more source

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

npj Biofilms and Microbiomes, 2022
The Clostridioides difficile pathogen is responsible for nosocomial infections. Germination is an essential step for the establishment of C. difficile infection (CDI) because toxins that are secreted by vegetative cells are responsible for the symptoms ...
Andrea Martinez Aguirre, Adegoke Oyeleye Adegbite, Joseph A. Sorg   +2 more
doaj   +1 more source

Bile salt evolution

Journal of Lipid Research, 1967
Viewed against the background of known or supposed biosynthetic pathways for cholic and chenodeoxycholic acids in man and laboratory animals, the chemical nature of bile salts in more primitive animals clearly indicates that evolution from C27, 5α ...
G.A.D. Haslewood
doaj   +1 more source

Human and rat bile acid–CoA:amino acid N -acyltransferase are liver-specific peroxisomal enzymes: Implications for intracellular bile salt transport [PDF]

Hepatology, 2007
Bile acid–coenzyme A:amino acid N -acyltransferase (BAAT) is the sole enzyme responsible for conjugation of primary and secondary bile acids to taurine and ...
Pellicoro, Antonella, van den Heuvel, Fiona A. J., Geuken, Mariska, Moshage, Han, Jansen, Peter L. M., Faber, Klaas Nico   +5 more
openaire   +2 more sources