Results 151 to 160 of about 949,943 (203)

Bile salt hydrolase catalyses formation of amine-conjugated bile acids. [PDF]

Nature
Rimal B, Collins SL, Tanes CE, Rocha ER, Granda MA, Solanki S, Hoque NJ, Gentry EC, Koo I, Reilly ER, Hao F, Paudel D, Singh V, Singh V, Yan T, Kim MS, Bittinger K, Zackular JP, Krausz KW, Desai D, Amin S, Coleman JP, Shah YM, Bisanz JE, Gonzalez FJ, Vanden Heuvel JP, Wu GD, Zemel BS, Dorrestein PC, Weinert EE, Patterson AD.   +30 more
europepmc   +1 more source

7β-Hydroxysteroid dehydratase Hsh3 eliminates the 7-hydroxy group of the bile salt ursodeoxycholate during degradation by <i>Sphingobium</i> sp. strain Chol11 and other <i>Sphingomonadaceae</i>. [PDF]

Appl Environ Microbiol
Richtsmeier P, Nedielkov R, Haring M, Yücel O, Elsner L, Lülf RH, Wöhlbrand L, Rabus R, Moeller H, Philipp B, Mueller FM.   +10 more
europepmc   +1 more source

Odevixibat: A Novel Bile Salt Inhibitor Treatment for Pruritus in Progressive Familial Intrahepatic Cholestasis. [PDF]

Cureus
Flattmann FE, Mohiuddin FS, Singh A, Tandon A, Lockett SJ, Hirsch JD, Mosieri CN, Kaye AM, Varrassi G, Ahmadzadeh S, Shekoohi S, Kaye AD.   +11 more
europepmc   +1 more source

High-Throughput Assessment of Bile Salt Export Pump Inhibition Using RapidFire-MS and DESI-MS. [PDF]

ACS Med Chem Lett
Li J, Morato NM, Westover LS, Abeywickrema P, Geng J, Piassek M, Harden D, Strambeanu I, Shi Z, Cooks RG, Meng J.   +10 more
europepmc   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Bert Groen, Folkert Kuipers, Jurre Hageman   +2 more
exaly   +2 more sources

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Bile Salt Metabolism:I. The Physiology of Bile Salts

Australian and New Zealand Journal of Medicine, 1977
Bile salts are synthesized in the liver from cholesterol, conjugated with glycine or taurine and secreted in bile with cholesterol and lecithin. The molar concentrations of these three lipids determine solubility of cholesterol in bile. Within the gastrointestinal lumen bile salts play an essential role in lipid absorption and faty transport.
A E, Cowen, C B, Campbell
openaire   +2 more sources

Bile Salt Metabolism:II. Bile Salts and Disease

Australian and New Zealand Journal of Medicine, 1977
Alterations of bile salt metabolism have been shown in numerous diseases. Liver damage results in elevated serum bile salt concentrations which may be useful as a sensitive index of hepatocellular disease. Changes in the relative proportions of the individual bile salts in serum occur with cholestasis.
C B, Campbell, A E, Cowen
openaire   +2 more sources

Bile Salt Roles in Bile-Salt-Stimulated Lipase Activity

Journal of Pediatric Gastroenterology and Nutrition, 1986
SummaryThe hydrolysis of 4‐nitrophenylacetate and phenylsalicylate, catalyzed by human milk lipase in the presence of a range of concentrations of sodium cholate, has been measured at pH 7.3 and 37.5°C, and maximum activity was observed for both substrates at 1 mmole/ dm−3 bile salt.
C J, O'Connor, P, Walde, R G, Wallace
openaire   +2 more sources

Bile salt diarrhea

Current Gastroenterology Reports, 2005
Alterations in bile acid metabolism and in the enterohepatic circulation are often associated with chronic diarrhea and should be considered when more common causes of chronic diarrhea have been excluded. Bile acid diarrhea most often occurs in disease or resection of the terminal ileum, in which there is increased exposure of the colonic mucosa to ...
Bruce W, Robb, Jeffrey B, Matthews
openaire   +2 more sources

Solubility of Bile Salts

Nature, 1969
BILE salts are detergent-like molecules which occur widely in living systems. The dihydroxy and trihydroxy bile salts have an extraordinary ability to solubilize insoluble lipids such as phospholipids1–5, monoglycerides6 and long chain alkyl alcohols7.
D M, Small, W, Admirand
openaire   +2 more sources