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Bile Salts

2013
Bile salts play a crucial role in hepatobiliary and intestinal homeostasis and digestion. The liver synthesizes primary bile salts from cholesterol. Enzymatic modifications during their enterohepatic circulation lead to the formation of secondary and tertiary bile salts.
Maillette de Buy Wenniger, Lucas   +2 more
openaire   +1 more source

Bile salts and cholestasis

Digestive and Liver Disease, 2010
Bile salts have a crucial role in hepatobiliary and intestinal homeostasis and digestion. Primary bile salts are synthesized by the liver from cholesterol, and may be modified by the intestinal flora to form secondary and tertiary bile salts. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
Maillette de Buy Wenniger, Lucas   +1 more
openaire   +3 more sources

Bile salts and hydrodynamics of bile formation

Journal of Hepatology, 1989
We report a novel method to assess bile secretory pressure using a Statham pressure transducer. The studies were performed in vivo in male Sprague-Dawley rats under pentobarbital anesthesia. Maximal secretory pressure averaged 21.8 +/- 1.1 (S.D.) cmH2O.
Cotting, J., Reichen, J.
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Bile Salt Structure and Phase Equilibria in Aqueous Bile Salt and Bile Salt-Lecithin Systems

Hepatology, 1984
The hydrophilic-hydrophobic balance of bile salt monomers can be readily quantified by their elution sequence during reverse-phase high-performance liquid chromatography. Such studies have demonstrated that subtle variations in bile salt structure have profound effects on the hydrophilic-hydrophobic balance of ...
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Effects of bile salts on bile formation in rabbits

Life Sciences, 1986
The effects of different species of bile salts: deoxycholate, taurochenodeoxycholate, ursodeoxycholate, glycodeoxycholate, tauroursodeoxycholate, chenodeoxycholate and cholate (DCA, TCDC, UDCA, GDCA, TUDC, CDCA, CA) on bile secretion were examined in anesthetized rabbits using two different infusion routes.
K, Miyasaka, K, Kitani
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The role of bile salts in digestion

Advances in Colloid and Interface Science, 2011
Bile salts (BS) are bio-surfactants present in the gastrointestinal tract (GIT) that play a crucial role in the digestion and absorption of nutrients. The importance of BS for controlled release and transport of lipid soluble nutrients and drugs has recently stimulated scientific interest in these physiological compounds.
Julia Maldonado-Valderrama   +3 more
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Calcium binding to bile salts

Chemistry and Physics of Lipids, 1991
Calcium binding to bile salt monomers and micelles is an important issue with respect to the possible (but rare) precipitation of calcium bile salts in the gallbladder. In the present work the binding of Ca2+ to six bile salts was measured in solutions containing 2 to 100 mM bile salts by means of a calcium-sensitive dye, murexide, which determines the
E, Baruch   +3 more
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The solubilization of quinine by bile salts

Journal of the American Pharmaceutical Association (Scientific ed.), 1947
Abstract From turbidimetric titrations of bile salts with quinine and turbidity‐concentration curves of colloidal solutions of quinine‐dehydrocholic acid and tauroglycocholic acid complexes, it has been concluded that solubilization takes place through the formation of micelles composed of quinine and bile salts.
S, MUKHERJEE, R P, BANERJEE
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Bile salts and platelet aggregation

Experientia, 1971
Nachweis, dass der Zusatz von Gallensaure die Aggregation menschlicher Plattchen im Plasma in vitro herbeifuhren kann und dass die Saure selbst in den Plattchen vorhanden sein durfte.
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Bile Salts and Lipolysis

Enzymologia biologica et clinica, 1968
A, Stork, E, Fabian, J, Sponarová
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