Results 101 to 110 of about 399,922 (291)

Bilosomes as a Versatile Drug Delivery System: Preparation Techniques and Biomedical Application [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences
Bilosomal are considered as nano structures with bile salts incorporated into the lipid bilayer of the membrane are abundant. Drug-loaded bilosomes have received considerable attention as drug delivery systems for a variety of drugs.
Shadeed Gad   +4 more
doaj   +1 more source

Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): in vitro characterization and improved corneal permeation

open access: yes, 2013
Yikang Dai,1 Rui Zhou,2 Lin Liu,1 Yi Lu,2 Jianping Qi,2 Wei Wu21Department of Ophthalmology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 2Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy ...
Liu L, Qi J, Lu Y, Zhou R, Wu W, Dai Y
core  

Effects of an Organic Acid Blend on Growth Performance, Redox Homeostasis, and Intestinal Microbiota of Broilers in an Antibiotic‐Free Production System Under Winter Environmental Challenges

open access: yesAnimal Research and One Health, EarlyView.
Schematic summary of the effects of organic acids on growth performance and gut health‐related parameters in broilers. ABSTRACT This study was conducted to evaluate the effects of an organic acid blend on growth performance, redox homeostasis, and intestinal microbiota of broilers raised in an antibiotic‐free system during the winter season in China ...
Rong‐Hui Huang   +11 more
wiley   +1 more source

A Comparison of the Crystallization Inhibition Properties of Bile Salts

open access: yes, 2016
Bile salts are natural surfactants present in the human gastrointestinal tract. Therefore, it is essential to consider their effect on the dissolution and crystallization tendency of oral drug formulations.
Na Li (6550)   +7 more
core   +1 more source

Beyond Protein Synthesis: The Multifunctional Role of Functional Amino Acids in Modulating Meat Quality in Ruminants

open access: yesAnimal Research and One Health, EarlyView.
Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu   +5 more
wiley   +1 more source

Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni   +20 more
wiley   +1 more source

Alteration of Bile Salts by Bacteria.

open access: yesExperimental Biology and Medicine, 1962
SummaryThe ability of a variety of common intestinal microrganisms to grow in bile salt-containing media and to alter the structure of those bile salts was studied. Strains of Escherichia coli, Proteus vulgaris, and Streptococcus faecalis were adapted by serial transfer in cholate-containing media to grow more rapidly in high concentrations of cholate ...
O W, PORTMAN   +3 more
openaire   +2 more sources

Protection against hydrophobic bile salt-induced cell membrane damage by liposomes and hydrophilic bile salts

open access: yes, 1993
Under physiological circumstances, cell membrane damage is not evident in biliary systems, despite the fact that hydrophobic bile salts are known to induce such damage by their detergent effects. The aim of this study was to determine the cytoprotective
S. Tazuma, H. Sagawa, G. Kajiyama
core   +1 more source

Controllable engineered probiotic microspheres for treating ulcerative colitis: A cascade enzyme‐catalyzed strategy to restore intestinal redox homeostasis

open access: yesBMEMat, EarlyView.
A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao   +9 more
wiley   +1 more source

Evolution of the bile salt nuclear receptor FXR in vertebrates*s⃞

open access: yesJournal of Lipid Research, 2008
Bile salts, the major end metabolites of cholesterol, vary significantly in structure across vertebrate species, suggesting that nuclear receptors binding these molecules may show adaptive evolutionary changes.
Erica J. Reschly   +6 more
doaj   +1 more source

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