Results 21 to 30 of about 8,121,841 (424)

Binding sites analyser (BiSA): software for genomic binding sites archiving and overlap analysis. [PDF]

open access: yesPLoS ONE, 2014
Genome-wide mapping of transcription factor binding and histone modification reveals complex patterns of interactions. Identifying overlaps in binding patterns by different factors is a major objective of genomic studies, but existing methods to archive ...
Matloob Khushi   +3 more
doaj   +1 more source

Galactoside-Binding Site in LacY [PDF]

open access: yesBiochemistry, 2014
Although an X-ray crystal structure of lactose permease (LacY) has been presented with bound galactopyranoside, neither the sugar nor the residues ligating the sugar can be identified with precision at ~3.5 Å. Therefore, additional evidence is important for identifying side chains likely to be involved in binding.
Jiang, Xiaoxu   +4 more
openaire   +6 more sources

Computing the protein binding sites [PDF]

open access: yesBMC Bioinformatics, 2011
Identifying the location of binding sites on proteins is of fundamental importance for a wide range of applications including molecular docking, de novo drug design, structure identification and comparison of functional sites. Structural genomic projects are beginning to produce protein structures with unknown functions.
Lusheng Wang, Fei Guo, Fei Guo
openaire   +4 more sources

Monolayer Gas Adsorption on Graphene-Based Materials: Surface Density of Adsorption Sites and Adsorption Capacity

open access: yesSurfaces, 2020
Surface density of adsorption sites on an adsorbent (including affinity-based sensors) is one of the basic input parameters in modeling of process kinetics in adsorption based devices.
Olga Jakšić   +3 more
doaj   +1 more source

Interaction of haemin with albumin-based macroporous cryogel: Adsorption isotherm and fluorescence quenching studies

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Albumin-based cryogels for capturing haemin were synthesised by crosslinking different biomolecules, bovine serum albumin (BSA) and ovalbumin (OVA). The impact of the protein and coupling agent concentrations on cryogel’s mechanical properties, swelling ...
Solmaz Hajizadeh   +2 more
doaj   +1 more source

Being a binding site: Characterizing residue composition of binding sites on proteins [PDF]

open access: yesBioinformation, 2007
The Protein Data Bank contains the description of more than 45,000 three-dimensional protein and nucleic-acid structures today. Started to exist as the computer-readable depository of crystallographic data complementing printed articles, the proper interpretation of the content of the individual files in the PDB still frequently needs the detailed ...
Ivan, G, Szabadka, Z, Grolmusz, V
openaire   +3 more sources

Distinct In Vitro Binding Profile of the Somatostatin Receptor Subtype 2 Antagonist [177Lu]Lu-OPS201 Compared to the Agonist [177Lu]Lu-DOTA-TATE

open access: yesPharmaceuticals, 2021
Treatment of neuroendocrine tumours with the radiolabelled somatostatin receptor subtype 2 (SST2) peptide agonist [177Lu]Lu-DOTA-TATE is effective and well-established.
Rosalba Mansi   +3 more
doaj   +1 more source

Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABAA and Nicotinic Acetylcholine Receptors

open access: yesToxins, 2021
Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABAA receptors (GABAARs) with different efficacy, an important role of the TFTs ...
Lina Son   +7 more
doaj   +1 more source

Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2

open access: yesComputational and Structural Biotechnology Journal, 2014
We have shown earlier that Kir2 channels are suppressed by the elevation of membrane cholesterol. Moreover, it is also well known that activation of Kir channels is critically dependent on a regulatory phospholipid, phosphatidylinositol-4,5-bisphosphate (
Avia Rosenhouse-Dantsker   +2 more
doaj   +1 more source

Crystal engineering of porous coordination networks for C3 hydrocarbon separation

open access: yesSmartMat, 2021
C3 hydrocarbons (HCs), especially propylene and propane, are high‐volume products of the chemical industry as they are utilized for the production of fuels, polymers, and chemical commodities.
Mei‐Yan Gao   +3 more
doaj   +1 more source

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