Results 41 to 50 of about 546,030 (294)

Opioids in COVID-19: Two Sides of a Coin

Frontiers in Pharmacology, 2022
Introduction: The treatment of most severe COVID-19 patients included the large-scale use of sedatives and analgesics–possibly in higher doses than usual–which was reported in the literature.
Camila Vantini Capasso Palamim, Camila Vantini Capasso Palamim, Matheus Negri Boschiero, Matheus Negri Boschiero, Aléthea Guimarães Faria, Aléthea Guimarães Faria, Felipe Eduardo Valencise, Felipe Eduardo Valencise, Fernando Augusto Lima Marson, Fernando Augusto Lima Marson   +9 more
doaj   +1 more source

OrgTrace – No Difference in Levels of Bioactive Compounds found in Crops from Selected Organic and Conventional Cultivation Systems [PDF]

, 2011
The objective of the present study was to compare the content of selected bioactive compounds in organically and conventionally grown crops, and to evaluate if the ability of the crops to synthesize selected secondary metabolites was systematically ...
Bysted, Anette, Halekoh, Ulrich, Husted, Søren, Knuthsen, Pia, Laursen, Kristian Holst, Madsen, Katja H, Nielsen , John, Soeltoft, Malene   +7 more
core  

Biological Activities of Extracts from Sumac (Rhus spp.): A Review [PDF]

, 2007
Sumac is the common name for a genus (Rhus) that contains over 250 individual species of flowering plants in the family Anacardiaceae. These plants are found in temperate and tropical regions worldwide, often grow in areas of marginal agricultural ...
Giuseppe Mazza, Sierra Rayne
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Isolation and Genetic Identification of Endophytic Lactic Acid Bacteria From the Amazonian Açai Fruits: Probiotics Features of Selected Strains and Their Potential to Inhibit Pathogens

Frontiers in Microbiology, 2021
The açai palm (Euterpe oleracea) is native to the Amazon basin, a humid tropical forest. High levels of total mesophilic bacteria with high diversity have been consistently reported in açai fruits.
Suenne Taynah Abe Sato, Joana Montezano Marques, Joana Montezano Marques, André da Luz de Freitas, Raphaela Cristina Sanches Progênio, Márcio Roberto Teixeira Nunes, Janaína Mota de Vasconcelos Massafra, Fábio Gomes Moura, Hervé Rogez   +8 more
doaj   +1 more source

Bioactive metabolites in crops, diets and human samples [PDF]

, 2007
The objective of the PhD-project is to characterize bioactive metabolites, such as polyphenols, in selected crops and investigate the influence of different organic farming systems on the ability of crops to synthesize bioactive compounds with health ...
Knuthsen, Pia, Nielsen, John, Søltoft, Malene   +2 more
core  

Bioactive glass-ceramic scaffolds from novel 'inorganic gel casting' and sinter-crystallization [PDF]

, 2017
Highly porous wollastonite-diopside glass-ceramics have been successfully obtained by a new gel-casting technique. The gelation of an aqueous slurry of glass powders was not achieved according to the polymerization of an organic monomer, but as the ...
Bernardo, Enrico, Elsayed, HAMADA SAID ABDELWAHAB, Ferroni, Letizia, Gardin, Chiara, Romero, Acacio Rinc\uf3n, Zavan, Barbara   +5 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

In Vitro and In Silico Investigations of Natural Compounds with Predicted Activity against Neuroblastomas

Chemistry Proceedings, 2022
In the present study, the ability of an ethanolic extract from Stokesia laevis to inhibit the development of human glioblastoma cell line U87 has been investigated. Cytotoxic activity has been estimated at 78% in comparison to normal human astrocyte cell
Lucia Camelia Pirvu, Georgeta Neagu, Özge Çığ, Adrian Albulescu, Lucia Pintilie, Amalia Stefaniu   +5 more
doaj   +1 more source

Extraction of Anthocyanins and Total Phenolic Compounds from Acai (Euterpe oleracea Mart.) Using an Experimental Design Methodology. Part 2: Ultrasound-Assisted Extraction [PDF]

, 2020
Two optimized methods for ultrasound-assisted extraction were evaluated for the extraction of two types of acai bioactive compounds: Total anthocyanins (TAs) and total phenolic compounds (TPCs).
Aliaño González, María José, Ayuso Vilacides, Jesús, Carrera Fernández, Ceferino Adrián, Espada Bellido, Estrella, Fernández Barbero, Gerardo, Ferreiro González, Marta, Palma Lovillo, Miguel, Álvarez Saura, José Ángel   +7 more
core   +1 more source