Results 51 to 60 of about 90,186 (160)
Bioactive Peptides in Milk Products.
Journal of Food Technology in Africa, 2000 Some peptides produced in vitro or in vivo by enzymatic hydrolysis of caseins and whey protein can affect some biological functions of the body and therefore they are called bioactive peptides. In this paper the physiological significance of bioactive peptides is reviewed and the analytical methods for their purification and determination are ...
A. TIRELLI, I. De Noni, P. Resmini
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Discovery of Bioactive Peptides Through Peptide Scanning
Journal of Peptide ScienceABSTRACTTherapeutic peptides targeted at various diseases are becoming increasingly relevant for the pharmaceutical industry. Several of these drugs were originally designed by mimicking a segment of a protein of interest. As such, protein mimicry represents a promising strategy both in immunology, for the identification of B‐ and T‐cell epitopes, as ...
Debora Iaculli, Steven Ballet
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Prokineticin 2 Plays a Pivotal Role in Psoriasis
EBioMedicine, 2016 Psoriasis is histologically characterized by keratinocytes (KC) hyperproliferation, inflammation, and increased angiogenesis, but the pathological factor responsible for these symptoms is unknown.
Xiaoqin He +11 more
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Characterization of Alpha-Bungarotoxin Antibodies Prepared by Different Strategies
ToxinsThe preparation of an antibody to treat snake envenomation requires a large amount of snake venom. In China, only four types of anti-snake venom sera are clinically available, and the production and immunization strategies for clinically approved anti ...
Huijuan Lu +6 more
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A clinical and mechanistic study of topical borneol‐induced analgesia
EMBO Molecular Medicine, 2017 Bingpian is a time‐honored herb in traditional Chinese medicine (TCM). It is an almost pure chemical with a chemical composition of (+)‐borneol and has been historically used as a topical analgesic for millennia. However, the clinical efficacy of topical
Shu Wang +11 more
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Ghrelin is essential for lowering blood pressure during torpor
Frontiers in EndocrinologyIntroductionDaily torpor is an active hypothermic phenomenon that is observed in some mammals and birds during fasting. A decrease in blood pressure has also been observed in torpor; however, there remains a lack of knowledge of the underlying mechanism.
Kazuma Matsui +4 more
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Anti-HIV-1 Activity of the Integrase Strand Transfer Inhibitor ACC017
VirusesHIV-1 integrase strand transfer inhibitors (INSTIs) are pivotal to antiretroviral therapy. However, the emergence of drug-resistant mutations necessitates the development of new agents. Here, we present ACC017 as a novel INSTI candidate.
Meng-Di Ma +8 more
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MicroorganismsThe venoms of Theraphosidae spiders have evolved into diverse natural pharmacopeias through selective pressures. Cryptococcus neoformans is a global health threat that frequently causes life-threatening meningitis and fungemia, particularly in ...
Brenda B. Michira +10 more
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