Neuroplastin Modulates Anti-inflammatory Effects of MANF
Summary: Endoplasmic reticulum (ER) stress is known to induce pro-inflammatory response and ultimately leads to cell death. Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an ER-localized protein whose expression and secretion is induced by
Takuya Yagi +6 more
doaj +1 more source
Yeast lunapark regulates the formation of trans-Sey1p complexes for homotypic ER membrane fusion
Summary: The endoplasmic reticulum (ER) consists of the nuclear envelope and a connected peripheral network of tubules and interspersed sheets. The structure of ER tubules is generated and maintained by various proteins, including reticulons, DP1/Yop1p ...
Eunhong Jang +8 more
doaj +1 more source
ADP-ribosylation factor 6 (ARF6) bidirectionally regulates dendritic spine formation depending on neuronal maturation and activity [PDF]
Recent studies have reported conflicting results regarding the role of ARF6 in dendritic spine development, but no clear answer for the controversy has been suggested.
Kim Y. +6 more
core +1 more source
Laboratory of molecular biology and clinical biochemistry, Institute of Animal Biology NAAS: the history and present state [PDF]
The Laboratory of molecular biology and clinical biochemistry was established with the foundation of Scientific Production Center (SPC) for the study of prion infections in 2001.
I. M. Petrukh +5 more
core +1 more source
This is a problem-based learning case for a medical biochemistry-molecular biology course suitable for first- or second-year medical students. The case is that of a young girl who is diagnosed as a compound heterozygote for Gaucher disease and is treated
Marshall Anderson
doaj +1 more source
Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors
Summary: The 30+ unique ligands of the TGFβ family signal by forming complexes using different combinations of type I and type II receptors. Therapeutically, the extracellular domain of a single receptor fused to an Fc molecule can effectively neutralize
Erich J. Goebel +14 more
doaj +1 more source
EFFECTIVENESS OF ACADEMIC ADVICE IN THE LEARNING OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
Due to the importance of solving the low academic performance of medical students, a constant problem in higher education, and which is a widely researched multifactorial variable, the following research work was proposed to determine the ...
Sandra Rosales-Gracia +4 more
doaj +1 more source
The biochemistry and molecular biology of chlorophyll breakdown [PDF]
Chlorophyll breakdown is one of the most obvious signs of leaf senescence and fruit ripening. The resulting yellowing of leaves can be observed every autumn, and the color change of fruits indicates their ripening state. During these processes, chlorophyll is broken down in a multistep pathway, now termed the 'PAO/phyllobilin' pathway, acknowledging ...
Kuai, Benke +2 more
openaire +4 more sources
Gli-similar 3 (Glis3) is Krüppel-like transcription factor associated with the transcriptional regulation of insulin. Mutations within the Glis3 locus have been implicated in a number of pathologies including diabetes mellitus and hypothyroidism. Despite
Tyler M. Hoard +3 more
doaj +1 more source
N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis
Summary: Red blood cells supply the oxygen required for all human cells and are in demand for emerging blood-loss therapy. Here we identified N6-methyl-2′-deoxyadenosine (6mdA) as an agonist that promotes the hyperproliferation of burst-forming unit ...
Yao Li, Zi-Yu Liang, Hai-Lin Wang
doaj +1 more source

