Results 41 to 50 of about 576,788 (310)
iScience, 2022 Summary: The EphA2 receptor tyrosine kinase activates signaling pathways with different, and sometimes opposite, effects in cancer and other pathologies.
Maricel Gomez-Soler +7 more
doaj +1 more source
Epoxide hydrolases: biochemistry and molecular biology [PDF]
Chemico-Biological Interactions, 2000 Epoxides are organic three-membered oxygen compounds that arise from oxidative metabolism of endogenous, as well as xenobiotic compounds via chemical and enzymatic oxidation processes, including the cytochrome P450 monooxygenase system. The resultant epoxides are typically unstable in aqueous environments and chemically reactive.
A J, Fretland, C J, Omiecinski
openaire +2 more sources
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
Liberal Academic Conservatism, Conservative Academic Liberalism, and Biochemistry: A History of the Academic Faculty of Biochemistry and Molecular Biology, College of Biological Sciences, The Ohio State University [PDF]
, 1969 Prepared for the Centennial of The Ohio State University.The Department of Agricultural Chemistry, 1882-1896 -- The Department of Agricultural Chemistry, College of Agriculture, 1896-1916 -- The Department of Agricultural Chemistry Soils, College of ...
Deatherage, Fred E., 1913-
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Bioinformatic approaches for the structure and function of membrane proteins [PDF]
, 2019 Membrane proteins play important roles in the biology of the cell, including intercellular communication and molecular transport. Their well-established importance notwithstanding, the high-resolution structures; of membrane proteins remain elusive due ...
Nam, HJ, Kim, S, Jeon, J
core +1 more source
N6-methyladenosine (m6A) modification of TXNIP in 3′UTR instigates abdominal aorta aneurysm in mice
iScienceSummary: The thioredoxin-interacting protein (TXNIP) pathway is a central regulator of oxidative stress and contributes to vascular pathology. Here, we define how stress-responsive mRNA methylation controls TXNIP expression and drives abdominal aortic ...
Fransky Hantelys +2 more
doaj +1 more source
A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control
PLoS Biology, 2005 Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Vanácová Stepánka +8 more
doaj +1 more source
Biological consequences of structural and functional proteasome diversity
Heliyon, 2018 Cell homeostasis and regulation of metabolic pathways are ensured by synthesis, proper folding and efficient degradation of a vast amount of proteins.
Alexey V. Morozov, Vadim L. Karpov
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
HP1β recruits RING1A to ubiquitinate histone H2A for BRCA1-mediated resection of double-stand breaks
iScienceSummary: Efficient DNA double-strand break (DSB) repair by homologous recombination (HR), as initiated by BRCA1 recruitment orchestrated by histone and non-histone proteins, is critical to genome stability, replication, transcription, and cancer ...
Vijaya Charaka +13 more
doaj +1 more source