Results 71 to 80 of about 956,419 (320)

Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics. [PDF]

, 2015
Microtubule dynamics and polarity stem from the polymerization of αβ-tubulin heterodimers. Five conserved tubulin cofactors/chaperones and the Arl2 GTPase regulate α- and β-tubulin assembly into heterodimers and maintain the soluble tubulin pool in the ...
Al-Bassam, Jawdat, Corbett, Kevin D, Jia, Weitao, Le, Sinh, Leary, Julie, Moore, Jeffrey K, Nithianantham, Stanley, Seto, Elbert   +7 more
core   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Corrigendum to “Effects of therapeutic hypothermia on the gut microbiota and metabolome of infants suffering hypoxic-ischemic encephalopathy at birth” [Int. J. Biochem. Cell Biol. 93 (December) (2017), 110-118] [PDF]

, 2019
peer-reviewedCorrigendum Refers to: Watkins, C., Murphy, K., Yen, S., Carafa, I., Dempsey, E., O’Shea, C., Vercoe, E., Ross, R., Stanton, C. and Ryan, C. (2017).
Allen-Vercoe, Emma, Carafa, Ilaria, Dempsey, Eugene M., Murphy, Kevin M., O’ Shea, C. A., Ross, R Paul, Ryan, Cornelius A., STANTON, CATHERINE, Watkins, Claire, Yen, Sandi   +9 more
core   +1 more source

Pleurotus ostreatus as a model mushroom in genetics, cell biology, and material sciences

Applied Microbiology and Biotechnology
Pleurotus ostreatus , also known as the oyster mushroom, is a popular edible mushroom cultivated worldwide. This review aims to survey recent progress in the molecular genetics of this fungus and demonstrate its potential as a model mushroom for future ...
T. Nakazawa, Moriyuki Kawauchi, Yuitsu Otsuka, Jun-Woo Han, D. Koshi, Kim Schiphof, Lucía Ramírez, A. Pisabarro, Yoichi Honda   +8 more
semanticscholar   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. [PDF]

, 2013
The secretory pathway of eukaryotic cells packages cargo proteins into COPII-coated vesicles for transport from the endoplasmic reticulum (ER) to the Golgi.
Adams, Elizabeth, Bai, Yongsheng, Baines, Andrea, Bajaj, Kanika, Chen, Xiao-Wei, Ginsburg, David, Lin, Jiandie, Liu, Hui-Hui, Ma, Danjun, Meng, Zhuo-Xian, Sartor, Maureen A, Schekman, Randy, Wang, He, Yi, Zhengping, Young, Stephen G, Yu, Genggeng, Zhang, Bin, Zhang, Pengcheng   +17 more
core   +1 more source

Detection of Extracellular Vesicle RNA Using Molecular Beacons

iScience, 2020
Summary: Extracellular vesicles (EVs) have recently emerged as intercellular conveyors of biological information and disease biomarkers. Identification and characterization of RNA species in single EVs are currently challenging.
Getulio Pereira de Oliveira, Jr., Eric Zigon, Gaenna Rogers, Danny Davodian, Shulin Lu, Tijana Jovanovic-Talisman, Jennifer Jones, John Tigges, Sanjay Tyagi, Ionita Calin Ghiran   +9 more
doaj  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]

, 2015
The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D, Moeller, Arne, Rosenberg, Scott C, Speir, Jeffrey A, Su, Tiffany Y, Ye, Qiaozhen   +5 more
core   +2 more sources

Impact of Completion of a Pre-Pharmacy Biochemistry Course and Competency Levels in Pre-Pharmacy Courses on Pharmacy Student Performance

Pharmacy, 2019
Poor performance in foundational science courses, which are usually taken during the first or second year of pharmacy school, can have several negative consequences including increases in student drop-out rates and increases in the number of dismissals ...
Ruth Vinall, Parto Khansari, Jason McDowell, L. Douglas Ried, Eugene Kreys   +4 more
doaj   +1 more source