Results 1 to 10 of about 1,493,364 (293)

Concerted Complex Assembly and GTPase Activation in the Chloroplast Signal Recognition Particle [PDF]

, 2011
The universally conserved signal recognition particle (SRP) and SRP receptor (SR) mediate the cotranslational targeting of proteins to cellular membranes.
Chandrasekar, Sowmya, Neher, Saskia, Nguyen, Thang X., Shan, Shu-ou, Walter, Peter   +4 more
core   +3 more sources

Disposition and Challenges of Alternative to Physical Classroom Teaching and Learning in a Pandemic; an Appraisal of Biochemistry Students COVID-19 Learning with WhatsApp

Galician Medical Journal, 2020
The objective of the study was to assess the disposition and challenges of students towards teaching and learning of biochemistry through WhatsApp. Materials and Methods. The study was a cross-sectional survey which had 200 level (Second Year) and 400
Peter Agbadobi Uloku Ossai, Chukwudi Ogwu, Patrick Chukwuyenum Ichipi-Ifukor, Fidelis Ifeakachuku Achuba   +3 more
doaj   +1 more source

Planning an Objective and Need Based Curriculum: The Logistics with Reference to the Undergraduate Medical Education in Biochemistry [PDF]

Journal of Clinical and Diagnostic Research, 2013
Purpose: The medical education is recently being transformed into several domains in order to adapt to the need and the value based academics which is required for the quality doctors who serve the community. Presently, the biochemistry curricula for
Ramesh Ramasamy, Niranjan Gopal, Srinivasan A R, Sathish Babu Murugaiyan   +3 more
doaj   +1 more source

Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays

Toxins, 2020
Botulinum neurotoxins (BoNTs) are potent neurotoxins produced by bacteria, which inhibit neurotransmitter release, specifically in their physiological target known as motor neurons (MNs).
Maren Schenke, Brit-Maren Schjeide, Gerhard P. Püschel, Bettina Seeger   +3 more
doaj   +1 more source

X-ray Crystallographic Characterization of the Co(II)-substituted Tris-bound Form of the Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]

, 2007
The X-ray crystal structure of the Co(II)-loaded form of the aminopeptidase from Aeromonas proteolytica ([CoCo(AAP)]) was solved to 2.2 Å resolution. [CoCo(AAP)] folds into an α/β globular domain with a twisted β-sheet hydrophobic core sandwiched between
Bennett, Brian, Holz, Richard C., Moulin, Aaron, Munih, Petra, Petsko, Gregory A., Ringe, Dagmar, Stamper, Carin   +6 more
core   +1 more source

MHC2-SCALE enhances identification of immunogenic neoantigens

iScience
Summary: Recent studies suggest that CD4+ T cells can exert potent anti-tumor effects and improve immunotherapy efficacy by aiding CD8+ T cells. However, characterizing the mechanism of CD4+ T cells’ anti-tumor activity has been challenging due to ...
Joshua G. Gober, Aude-Hélène Capietto, Reyhane Hoshyar, Martine Darwish, Richard Vandlen, Jonathan L. Linehan, Lélia Delamarre, Adel M. ElSohly   +7 more
doaj   +1 more source

Research opportunities in muscle atrophy [PDF]

Muscle atrophy in a weightless environment is studied. Topics of investigation include physiological factors of muscle atrophy in space flight, biochemistry, countermeasures, modelling of atrophied muscle tissue, and various methods of measurement of ...
Herbison, G. J., Talbot, J. M.
core   +1 more source

Technical pre-analytical effects on the clinical biochemistry of Atlantic salmon (Salmo salar L.) [PDF]

, 2016
Clinical biochemistry has long been utilized in human and veterinary medicine as a vital diagnostic tool, but despite occasional studies showing its usefulness in monitoring health status in Atlantic salmon (Salmo salar L.), it has not yet been widely ...
Ashby, A., Braceland, M., Eckersall, P.D., Haining, H., Houston, K., Matthews, C., Rodger, H.   +6 more
core   +1 more source

Structure-based inhibitors of amyloid beta core suggest a common interface with tau. [PDF]

, 2019
Alzheimer's disease (AD) pathology is characterized by plaques of amyloid beta (Aβ) and neurofibrillary tangles of tau. Aβ aggregation is thought to occur at early stages of the disease, and ultimately gives way to the formation of tau tangles which ...
Bowler, Jeannette, Cascio, Duilio, Eisenberg, David S, Glabe, Charles G, Gonen, Tamir, Griner, Sarah L, Murray, Kevin A, Philipp, Stephan, Rodriguez, Jose A, Sahay, Shruti, Sawaya, Michael R, Seidler, Paul, Sosna, Justyna, Yang, Tianxiao Peter   +13 more
core   +1 more source

Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem Interval [PDF]

, 2013
Death is likely to result in very extensive biochemical changes in all body tissues due to lack of circulating oxygen, altered enzymatic reactions, cellular degradation, and cessation of anabolic production of metabolites.
Donaldson, Andrea
core   +1 more source