Results 21 to 30 of about 1,493,364 (293)

Editorial: Research methods in biochemistry and biophysics

BBA Advances
Daniel E. Otzen
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Characterization of heterologously expressed Fibril, a shape and motility determining cytoskeletal protein of the helical bacterium Spiroplasma

iScience, 2022
Summary: Fibril is a constitutive filament-forming cytoskeletal protein of unidentified fold, exclusive to members of genus Spiroplasma. It is hypothesized to undergo conformational changes necessary to bring about Spiroplasma motility through changes in
Shrikant Harne, Pananghat Gayathri
doaj   +1 more source

In situ observation of mitochondrial biogenesis as the early event of apoptosis

iScience, 2021
Summary: Mitochondrial biogenesis is a cell response to external stimuli which is generally believed to suppress apoptosis. However, during the process of apoptosis, whether mitochondrial biogenesis occurs in the early stage of the apoptotic cells ...
Chang-Sheng Shao, Xiu-Hong Zhou, Yu-Hui Miao, Peng Wang, Qian-Qian Zhang, Qing Huang   +5 more
doaj   +1 more source

Towards molecular systems biology of gene transcription and regulation [PDF]

, 2010
Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, Patrick
core   +1 more source

Integrative approaches in cryogenic electron microscopy: Recent advances in structural biology and future perspectives

iScience, 2021
Summary: Cellular factories engage numerous highly complex “molecular machines” to perform pivotal biological functions. 3D structural visualization is an effective way to understand the functional mechanisms of these biomacromolecules.
Aneek Banerjee, Sayan Bhakta, Jayati Sengupta   +2 more
doaj   +1 more source

Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics

iScience, 2023
Summary: T cells become activated following one or multiple contacts with antigen-presenting cells. Calcium influx is a key signaling event elicited during these cellular interactions; however, it is unclear whether T cells recall and integrate calcium ...
Béatrice Corre, Yassine El Janati Elidrissi, Justine Duval, Mailys Quilhot, Gaëtan Lefebvre, Solène Ecomard, Fabrice Lemaître, Zacarias Garcia, Armelle Bohineust, Erica Russo, Philippe Bousso   +10 more
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Methods ‌ Laboratory ‌ Biochemistry

, 2021
با توجه به اهميت بيوشيمی پایه ای و بالينی برای آموزش دانشجویان علوم پزشکی و زیستی در این کتاب سعی شده است عالوه بر مرور مطالب پایه و مهم بيوشيمی به جنبههـای کـاربردی بيوشـيمی در شناخت و تشخيص بيماریها نيز اشاره گردد. مطالب در پانزده فصل جمع آوری شـده اسـت. در فصل اول رعایت شرایط ایمنی در آزمایشگاه و در فصل دوم آشنایی با وسایل آزمایشـگاه شـر داده شده که
openaire   +2 more sources

In vitro determination of hemoglobin A1c for diabetes diagnosis and management: technology update [PDF]

, 2014
It is fascinating to consider the analytical improvements that have occurred since glycated hemoglobin was first used in routine clinical laboratories for diabetes monitoring around 1977; at that time methods displayed poor precision, there were no ...
English, Emma, John, W Garry, Milosevich, Elise T   +2 more
core   +1 more source

Light-Triggered Electron Transfer between a Conjugated Polymer and Cytochrome C for Optical Modulation of Redox Signaling

iScience, 2020
Summary: Protein reduction/oxidation processes trigger and finely regulate a myriad of physiological and pathological cellular functions. Many biochemical and biophysical stimuli have been recently explored to precisely and effectively modulate ...
Ilaria Abdel Aziz, Marco Malferrari, Francesco Roggiani, Gabriele Tullii, Stefania Rapino, Maria Rosa Antognazza   +5 more
doaj   +1 more source

Improving self-directed learning ability of medical students using the blended teaching method: a quasi-experimental study

BMC Medical Education, 2023
Background Self-directed learning (SDL) is one of the most important abilities for medical students in terms of their future clinical medical practice. During the blended teaching process, teachers can design a variety of learning activities to cultivate
Si Ying Lu, Xiang Peng Ren, Huang Xu, Dong Han   +3 more
doaj   +1 more source