Results 151 to 160 of about 85,054 (209)

Advances in neurotensin receptor 1-targeted molecular probes for tumor molecular imaging and therapy. [PDF]

Front Oncol
Liu C, Fu J, Tang S, Hu H, Guo H, Liu T, Wen L, Yang Y, Yang Y, Chen S, Yu L, Zhou H.   +11 more
europepmc   +1 more source

CDCA-Derived NE3TA Conjugate for Liver-Selective ⁶⁴Cu PET Imaging. [PDF]

ACS Omega
Wang H, Ren S, Bandara N, Zhang S, Fujimori R, Nguyen HH, Minh DDL, Rogers BE, Chong HS.   +8 more
europepmc   +1 more source

Development of a Highly Effective Bifunctional Ligand 2E-C-NETA for Targeted Lu-177 Therapy: Synthesis, Radiolabeling, In Vitro Stability, and In Vivo Biodistribution. [PDF]

ChemMedChem
Chen Y, Lee Y, Kang CS, Ren S, Chen Y, Wang H, Bandara N, Rogers BE, Chong HS.   +8 more
europepmc   +1 more source

Development and evaluation of the first-in-class nanobody based PET tracer targeting human inducible T-cell co-stimulator receptor. [PDF]

EJNMMI Res
Li J, Duan S, You W, Zhao Y, Li W, Xiao Z, Liu J.   +6 more
europepmc   +1 more source

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Biodegradation, biodistribution and toxicity of chitosan

Advanced Drug Delivery Reviews, 2010
Chitosan is a natural polysaccharide that has attracted significant scientific interest during the last two decades. It is a potentially biologically compatible material that is chemically versatile (-NH2 groups and various M(w)). These two basic properties have been used by drug delivery and tissue engineering scientists to create a plethora of ...
Kean, T., Thanou, M.
exaly   +4 more sources

In Vivo Bacteriophage Biodistribution

, 2017
At the dawn of the renaissance of bacteriophage therapy, the full acceptation of bacteriophages as anti-bacterial agents requires the determination of their basic pharmacokinetic parameters. Such data, known for all conventional drugs used in human and veterinary medicine, allow optimizing dose regimens, efficacy, and help to limit toxicity.
Dufour, Nicolas, Delattre, Raphaëlle, Debarbieux, Laurent   +2 more
openaire   +5 more sources

The biodistribution of metaiodobenzylguanidine

Seminars in Nuclear Medicine, 1992
M E T A I O D O B E N Z Y L G U A N I D I N E can be (MIBG) labeled with iodine-(123I) or 1311. The nearly ideal emission properties m a k e 1231 the preferred radionuclide? MIBG is a guanethidine analogue and was originally studied as a potential antihypertensive agent.
M T, Parisi, E D, Sandler, R S, Hattner
openaire   +2 more sources

Pharmacokinetics and Biodistribution of Nanoparticles

Molecular Pharmaceutics, 2008
Nanoparticles show their promise for improving the efficacy of drugs with a narrow therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based drugs. The pharmacokinetics (PK) and tissue distribution of the nanoparticles largely define their therapeutic effect and toxicity.
Shyh-Dar, Li, Leaf, Huang
openaire   +2 more sources

Biodistribution of photosensitizing agents

International Journal of Biochemistry, 1993
1. The features of neoplasia which predict for drug responsiveness are rapid growth and/or inefficient repair of damage, especially to DNA. 2. PDT has the advantage of yielding responses regardless of the growth fraction of a tumor, and repair appears to play only a minor role. 3. While an entirely different spectrum of tumors can be targeted with PDT,
D, Kessel, K, Woodburn
openaire   +2 more sources