Results 41 to 50 of about 439,213 (293)

Identification, biogenesis, function, and mechanism of action of circular RNAs in plants

open access: yesPlant Communications, 2023
Circular RNAs (circRNAs) are a class of single-stranded, closed RNA molecules with unique functions that are ubiquitously expressed in all eukaryotes.
Ruiqi Liu, Yu Ma, Tao Guo, Guanglin Li
doaj   +1 more source

Biogenesis of Cytochrome c in Neurospora crassa [PDF]

open access: yes, 1978
# 1. Precipitating antibodies specific for apocytochrome c and holocytochrome c, respectively, were employed to study synthesis and intracellular transport of cytochrome c in Neurospora in vitro. # 2.
Korb, Harald, Neupert, Walter
core   +1 more source

Platelet bioreactor: accelerated evolution of design and manufacture

open access: yesPlatelets, 2017
Platelets, responsible for clot formation and blood vessel repair, are produced by megakaryocytes in the bone marrow. Platelets are critical for hemostasis and wound healing, and are often provided following surgery, chemotherapy, and major trauma ...
Jonathan N. Thon   +2 more
doaj   +1 more source

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production

open access: yesCell Reports, 2015
Polyadenylation of mRNA is a key step in eukaryotic gene expression. However, despite the major impact of poly(A) tails on mRNA metabolism, the precise roles of poly(A)-binding proteins (PABPs) in nuclear mRNA biogenesis remain elusive.
Manfred Schmid   +5 more
doaj   +1 more source

Endoplasmic Reticulum Membrane and Contact Site Dynamics in Autophagy Regulation and Stress Response

open access: yesFrontiers in Cell and Developmental Biology, 2020
Autophagy mobilizes a variety of intracellular endomembranes to ensure a proper stress response and the maintenance of cellular homeostasis. While the process of de novo biogenesis of pre-autophagic structures is not yet fully characterized, the role of ...
Etienne Morel
doaj   +1 more source

Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation

open access: yesJournal of Extracellular Vesicles, 2021
Extracellular vesicles (EVs) are important players in cell to cell communication in reproductive systems. Notably, EVs have been found and characterized in the male reproductive tract, however, direct functional evidence for their importance in mediating
Natalie J. Foot   +10 more
doaj   +1 more source

CircRNA: A new class of targets for gastric cancer drug resistance therapy

open access: yesPathology and Oncology Research, 2023
Gastric cancer (GC) is one of the most common malignancies worldwide. Patients with advanced GC need palliative care to ensure survival. This includes the use of chemotherapy agents, such as cisplatin, 5-fluorouracil, oxaliplatin, paclitaxel, and ...
Ying Zheng   +15 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Co-targeting RNA Polymerases IV and V Promotes Efficient De Novo DNA Methylation in Arabidopsis. [PDF]

open access: yes, 2019
The RNA-directed DNA methylation (RdDM) pathway in plants controls gene expression via cytosine DNA methylation. The ability to manipulate RdDM would shed light on the mechanisms and applications of DNA methylation to control gene expression.
Chory, Joanne   +9 more
core   +2 more sources

Circular RNAs—The Road Less Traveled

open access: yesFrontiers in Molecular Biosciences, 2020
Circular RNAs are the most recent addition in the non-coding RNA family, which has started to gain recognition after a decade of obscurity. The first couple of reports that emerged at the beginning of this decade and the amount of evidence that has ...
Ashirbad Guria   +3 more
doaj   +1 more source

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