Results 111 to 120 of about 24,172 (228)

Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Pioglitazone is an antidiabetic drug acting as a peroxisome proliferator‐activated receptor γ (PPARγ) agonist and later repositioned as a monoamine oxidase B (MAO‐B) inhibitor. Despite promising preclinical premises, it showed a lack of efficacy in clinical trials as a treatment for neurodegenerative diseases.
Filippo Basagni, Maria Luisa Di Paolo, Antonio Laghezza, Giorgio Cozza, Francesco Piazzola, Laura Facci, Emma Marcolin, Elena Roggiolani, Luca Piemontese, Anna Minarini, Morena Zusso, Lisa Dalla Via, Michela Rosini   +12 more
wiley   +1 more source

Extending Cofactor‐Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow

ChemSusChem, Volume 19, Issue 15, 14 August 2026.
Engineered enzyme fusions bearing covalently tethered PEG–nicotinamide cofactors enable intramolecular cofactor retention and recycling within self‐sufficient biocatalytic nanomachines. These nanomachines support cofactor‐autonomous operation of complex redox multienzyme cascades under continuous‐flow conditions, as demonstrated in a 10‐step glucose‐to‐
Zinnia Dsouza, Jan‐Simon Jeshua Friedrichs, Okke Melse, Gerhard Schenk, Volker Sieber   +4 more
wiley   +1 more source

Biological Stability of Wine and Biogenic Amines [PDF]

, 2003
Biogenic amines should not be present in wines and they are always an indication for the activity of undesired micro-organisms with a high amino decarboxylase activity as found in the lactic acid bacteria Pediococcus damnosus.
Gafner, Jurg
core  

Biogenic Amines Determination in “Plant Milks” [PDF]

, 2019
“Plant milks” are water-based beverages, such as, extracts from cereals, pseudo-cereals, oil seeds, legumes or fruits. Plant milk consumption is rising in European and North American markets due to problems related to cow milk allergies, intolerances ...
Mattia Rapa, Ciano, Salvatore, Gobbi, Laura, Laura Gobbi, Roberto Ruggieri, Rapa, Mattia, Ruggieri, Roberto, Salvatore Ciano   +7 more
core   +1 more source

Optimized SPE‐HPLC‐FLD Method for the Simultaneous Determination of Olaparib, Propranolol, and Furosemide in Human Urine

Biomedical Chromatography, Volume 40, Issue 8, August 2026.
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris, Antonia Kalagia, Catherine K. Markopoulou   +2 more
wiley   +1 more source

Discovery of a Potent and Selective MAO‐B Inhibitor From a Donepezil‐Linked Chalcone Library With Promising Antiparkinsonian Activity

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A focused library of 19 donepezil‐linked chalcones (DLCs) was efficiently synthesised through microwave‐assisted Claisen‐Schmidt condensation and subsequently profiled for their inhibitory activities against cholinesterases (AChE and BuChE) as well as monoamine oxidases (MAO‐A and MAO‐B).
Azize Kirac‐Aydin, Bishnu Prasad Pandey, Satyajit Mohanty, Rupsa Mondal, Abanish Biswas, Ashok Kumar Pattnaik, Subodh Mondal, Vinay N. Basavanakatti, Nilüfer Bayrak, Venkatesan Jayaprakash, Hoon Kim, Amaç Fatih TuYuN   +11 more
wiley   +1 more source

Acumuation of biogenic amines in Lithuanian vegetables. [PDF]

, 2007
The amounts of biogenic amines (putrescine, histamine, cadaverine and tyramine) were determined in fresh vegetables: carrot, potato, beetroot, yellow pepper, cauliflower, broccoli, spinach and tomato.
Garmienė, Galina,, Šalaševičienė, Alvija,, Zaborskienė, Gintarė,, Jasutienė, Ina,   +3 more
core  

Identification of Volatile Odor Compounds in Extracts of Four Types of Herbaceous Plant Spices via GC × GC–O‐TOF MS

eFood, Volume 7, Issue 4, August 2026.
In this study, sensory evaluation, electronic nose, solid‐phase microextraction, and comprehensive two‐dimensional gas chromatography‐olfactometry‐time‐of‐flight mass spectrometry were used to analyze the volatile compounds and key odor‐active components in the extracts of sour horn, alfalfa, chicory, and fenugreek, and a total of 59 odor‐active ...
Suxing Tuo, Qinghui Jia, Shuang Bi, Yixin Dai, Ting Deng, Hongbing Lu, Jiaxiao Cai, Zifeng Li, Cheng Yang, Kejun Zhong, Bo Kong, Ye Liu   +11 more
wiley   +1 more source

Impact of Lactic Acid and Fermented Dairy‐Based Marinades on Quality Attributes and Biogenic Amine Formation in Turkey Breast Meat

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Turkey breast meat was marinated with lactic acid (pH 4.0), yogurt whey, kefir, or yogurt (1:1, w/w) for 24 h at 4°C and then cooked at 185°C for 15 min. Fermented dairy‐based marinades improved meat quality without promoting excessive biogenic amine formation.
Gülsüme Biçakci, Ercan Sarica
wiley   +1 more source

Effect of Steaming and Boiling on the Antioxidant Properties and Biogenic Amines Content in Green Bean (Phaseolus vulgaris) Varieties of Different Colours

Journal of Food Quality, 2017
Effects of boiling and steaming cooking methods were studied on total polyphenols, antioxidant capacity, and biogenic amines of three green bean varieties, purple, yellow, and green.
Raffaella Preti, Mattia Rapa, Giuliana Vinci   +2 more
doaj   +1 more source