Results 91 to 100 of about 8,062,393 (179)

ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Purinergic Receptor Complex: Generating Adenine Nucleotide-Sensitive Adenosine Receptors

Journal of Pharmacological Sciences, 2004
Adenosine A1 receptors (A1R) are able to form a heteromeric complex with P2Y1 receptors (P2Y1R) that generates A1R with P2Y1R-like agonistic pharmacology.
Kazuaki Yoshioka, Hiroyasu Nakata
doaj   +1 more source

Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. [PDF]

Transl Oncol, 2021
Bishnu A, Mehrotra M, Dhadve A, Dimri S, De A, Ray P.   +5 more
europepmc   +1 more source

Setting up a Bioluminescence Resonance Energy Transfer high throughput screening assay to search for protein/protein interaction inhibitors in mammalian cells.

Frontiers in Endocrinology, 2012
Each step of the cell life and its response or adaptation to its environment are mediated by a network of protein/protein interactions termed interactome.
Cyril eCouturier, Benoit eDeprez
doaj   +1 more source

Application of FRET- and BRET-based live-cell biosensors in deorphanization and ligand discovery studies on orphan G protein-coupled receptors

SLAS Discovery
Bioluminescence- and fluorescence-based resonance energy transfer assays have gained considerable attention in pharmacological research as high-throughput scalable tools applicable to drug discovery. To this end, G protein-coupled receptors represent the
Joanna J. Sajkowska, Choi Har Tsang, Paweł Kozielewicz   +2 more
doaj   +1 more source

Means and methods for bioluminescence resonance energy transfer (bret) analysis in a biological sample

The invention relates to the field of in vitro detection methods using luminescence. Provided is a sensor molecule for detecting an analyte of interest in a sample using bioluminescence resonance energy transfer (BRET), the sensor molecule comprising a ...
Johnsson, Kai Peter, Schena, Alberto, Griss, Rudolf   +2 more
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Bioluminescence Imaging of Inflammation in Vivo Based on Bioluminescence and Fluorescence Resonance Energy Transfer Using Nanobubble Ultrasound Contrast Agent

, 2019
Inflammation is an immunological response involved in various inflammatory disorders ranging from neurodegenerative diseases to cancers. Luminol has been reported to detect myeloperoxidase (MPO) activity in an inflamed area through a light-emitting ...
Yunxue Xu, Zhifei Dai (1515892), Jie Tang (46802), Jie Tang, Renfa Liu, Renfa Liu (1515895), Zhifei Dai, Yunxue Xu (4388278)   +7 more
core   +1 more source

Global DNA Methylation Detection System Using MBD-Fused Luciferase Based on Bioluminescence Resonance Energy Transfer Assay

, 2016
DNA methylation plays an important role in the regulation of gene expression. In normal cells, transposable elements that constitute approximately 45% of the human genome are highly methylated to silence their expression.
Yuji Baba (2534092), Wataru Yoshida (417955), Isao Karube (2868176)   +2 more
core   +1 more source

Unraveling ER dimerization dynamics in endocrine disruption based on a BRET-focused approach

Animal Cells and Systems
Endocrine-disrupting chemicals (EDCs) are exogenous compounds that interact with the estrogen receptor (ER), thereby disrupting estrogen-mediated signaling.
Soomin Yum, Haksoo Lee, Yong-Kook Kwon, Gunyoung Lee, Hye-Young Lee, HyeSook Youn, BuHyun Youn   +6 more
doaj   +1 more source

Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein–protein interactions in live cells

, 2006
Bioluminescence resonance energy transfer (BRET) is an increasingly popular technique for studying protein–protein interactions in live cells. It is particularly suitable for real-time monitoring of such interactions, however, the timescale over which ...
Dalrymple, Matthew B., Pfleger, Kevin D. G., Thomas, Walter G., Eidne, Karin A., Dromey, Jasmin R., Lim, Esther M. L.   +5 more
core   +1 more source

Energy transfer, Dakota Access Pipeline Project

Energy T ransfer Dakota Access Pipeline Project August 20, 2014 ENERGY TRANSFER USAGE DAPL0071137Suggested Meeting Agenda Introduction of Attendees Project Description Iowa and Illinois Counties Being Crossed USACE Jurisdictional Boundaries/Buffers ...
Energy Transfer Partners, L.P.;
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