Results 51 to 60 of about 143,872 (300)
Coactivator condensation at super-enhancers links phase separation and gene control [PDF]
, 2019 Super-enhancers (SEs) are clusters of enhancers that cooperatively assemble a high density of the transcriptional apparatus to drive robust expression of genes with prominent roles in cell identity.
Abraham, Brian J. +20 more
core +1 more source
Scaffolding viral protein NC nucleates phase separation of the HIV-1 biomolecular condensate.
Cell Reports, 2022 Membraneless biomolecular condensates (BMCs) contribute to the replication of a growing number of viruses but remain to be functionally characterized.
A. Monette +4 more
semanticscholar +1 more source
Mobile Localization in nonlinear Schrodinger lattices [PDF]
, 2004 Using continuation methods from the integrable Ablowitz-Ladik lattice, we have studied the structure of numerically exact mobile discrete breathers in the standard Discrete Nonlinear Schrodinger equation.
Ablowitz +37 more
core +2 more sources
Biomolecular condensates in autophagy regulation
Current Opinion in Cell Biology, 2021 Autophagy is an intracellular degradation system that contributes to cellular homeostasis. Autophagosome formation is a landmark event in autophagy, which sequesters and delivers cytoplasmic components to the lysosome for degradation. Based on selectivity, autophagy can be classified into bulk and selective autophagy, which are mechanistically distinct
Yuko, Fujioka, Nobuo N, Noda
openaire +2 more sources
mSphere, 2019 The social amoeba Dictyostelium discoideum’s proteome contains a vast array of simple sequence repeats, providing a unique model to investigate proteostasis. Upon conditions of cellular stress, D.
Stephanie Santarriaga +3 more
doaj +1 more source
When two became three: Shaping the nucleolus with Treacle
Cell Reports, 2023 The nucleolus is a multiphase biomolecular condensate responsible for the initial steps of ribosome biogenesis. Jaberi-Lashkari et al.1 report that Treacle, a protein associated with a craniofacial distortion disease, played an evolutionary role in the ...
Denis L.J. Lafontaine
doaj +1 more source
bioRxiv, 2022 Condensation/dissolution has become a widely acknowledged biological macromolecular assembly phenomenon in subcellular compartmentalization. MARTINI force field offers a coarse-grained protein model with a resolution that preserves molecular details with
Gül H. Zerze
semanticscholar +1 more source
Symmetry breaking and electrostatic attraction between two identical surfaces [PDF]
, 2008 By allowing the surface charge of one surface to affect the adsorption equilibrium of the other, we establish the existence of a long-range attractive interaction between two identical surfaces in an electrolyte containing polyvalent counterions with a ...
Chang, Hsueh-Chia, Plouraboué, Franck
core +3 more sources
Getting ready for DNA duplication
eLife, 2019 The discovery of a biomolecular condensate involved in DNA replication has wide-ranging implications.
Nina Y Yao, Michael E O'Donnell
doaj +1 more source
A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network. [PDF]
, 2019 Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic enzymes robustly form structures,
Begovich, Kyle +5 more
core +3 more sources