Results 61 to 70 of about 143,872 (300)
Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]
, 2017 In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
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HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain
eLife, 2021 Aberrant liquid-to-solid phase transitions of biomolecular condensates have been linked to various neurodegenerative diseases. However, the underlying molecular interactions that drive aging remain enigmatic.
Edgar E Boczek +18 more
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Quantum walk of a Bose-Einstein condensate in the Brillouin zone
, 2017 We propose a realistic scheme to implement discrete-time quantum walks in the Brillouin zone (i.e., in quasimomentum space) with a spinor Bose-Einstein condensate. Relying on a static optical lattice to suppress tunneling in real space, the condensate is
Alberti, Andrea, Wimberger, Sandro
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Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes [PDF]
, 2014 The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ∼5 nm must bind to nuclear transport receptors to overcome a selective ...
A Goryaynov +39 more
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Mechanisms of active regulation of biomolecular condensates [PDF]
Trends in Cell Biology, 2019 AbstractLiquid-liquid phase separation is a key organizational principle in eukaryotic cells, on par with intracellular membranes. It allows cells to concentrate specific proteins into condensates, increasing reaction rates and achieving switch-like regulation.
Söding, Johannes +4 more
openaire +5 more sources
Cell Communication and Signaling, 2021 Background Biomolecular condensates are non-stoichiometric assemblies that are characterized by their capacity to spatially concentrate biomolecules and play a key role in cellular organization.
Ryan J. Emenecker +2 more
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Nature Communications, 2021 KLF4, OCT4, SOX2 and MYC cooperate to reorganize chromatin during somatic cell reprogramming. Here the authors show that KLF4 forms a liquid-like biomolecular condensate that recruits OCT4 and SOX2, and that condensation of the isolated KLF4 DNA binding ...
Rajesh Sharma +11 more
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Shape Recovery of Deformed Biomolecular Droplets: Dependence on Condensate Viscoelasticity
bioRxiv, 2021 A theoretical study on the shape dynamics of phase-separated biomolecular droplets is presented, highlighting the importance of condensate viscoelasticity.
Huan‐Xiang Zhou
semanticscholar +1 more source
, 2003 We demonstrate that stabilization of solitons of the multidimensional Schrodinger equation with a cubic nonlinearity may be achieved by a suitable periodic control of the nonlinear term.
Montesinos, Gaspar D. +2 more
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Nfix Phase Separation Underlies Potential Mechanisms Of Craniofacial Abnormalities
International Dental JournalAim or purpose: This study explores alternative regulatory mechanisms of NFIX in Marshall-Smith syndrome (characterized by midface hypoplasia and micrognathia) and Malan syndrome (marked by macrocephaly and frontal bossing), hypothesizing that their ...
Jiayi Wang, Chenchen Zhou
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