Results 61 to 70 of about 10,366 (238)

Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions

Nature Communications, 2023
Prion-like low-complexity domains (PLCDs) are involved in the formation and regulation of distinct biomolecular condensates that form via phase separation coupled to percolation.
Mina Farag, Wade M. Borcherds, Anne Bremer, Tanja Mittag, Rohit V. Pappu   +4 more
doaj   +1 more source

Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components

Biomolecules, 2021
Biomolecular condensates, which assemble via the process of liquid–liquid phase separation (LLPS), are multicomponent compartments found ubiquitously inside cells.
Ignacio Sanchez-Burgos, Jorge R. Espinosa, Jerelle A. Joseph, Rosana Collepardo-Guevara   +3 more
doaj   +1 more source

Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. [PDF]

, 2017
As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis.
Antkowiak, Mark, Brust-Mascher, Ingrid, Castro, Noemi M, Cheung, Lee, Christensen, Lana N, Huang, Bo, Jao, Li-En, Jiang, Xueer, Mahe, Karan, Ou, Tingyoung, Sepulveda, Guadalupe, Yoon, Daniel   +11 more
core   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Pulsed Laser‐Assisted Phase Engineering of Multimetallic Colloidal Nanocrystals With Complex Compositions

Advanced Materials, EarlyView.
The engineering of colloidal nanocrystals with complex compositions has emerged as a highly active area of research within nanomaterials science. This review covers key aspects of colloidal solid‐solution nanocrystal formation using pulsed laser irradiation.
Marina T. Candela, Sergio Triviño‐Sánchez, Andrés Guerrero‐Martínez, Luis M. Liz‐Marzán, Guillermo González‐Rubio   +4 more
wiley   +1 more source

Diffusiophoresis promotes phase separation and transport of biomolecular condensates

Nature Communications
The internal microenvironment of a living cell is heterogeneous and comprises a multitude of organelles with distinct biochemistry. Amongst them are biomolecular condensates, which are membrane-less, phase-separated compartments enriched in system ...
Viet Sang Doan, Ibraheem Alshareedah, Anurag Singh, Priya R. Banerjee, Sangwoo Shin   +4 more
doaj   +1 more source

Transfer of BECs through discrete breathers in an optical lattice

, 2010
We study the stability of a stationary discrete breather (DB) on a nonlinear trimer in the framework of the discrete nonlinear Schr\"odinger equation (DNLS).
D. K. Campbell, H. Hennig, J. Dorignac, K. Ø. Rasmussen   +3 more
core   +3 more sources

Understanding Operando Water Management in Hydroxide‐Exchange‐Membrane Fuel Cells

Advanced Materials Interfaces, EarlyView.
Effective water management is vital for high‐performance hydroxide‐exchange‐membrane fuel cells. Using a custom water‐flux station, this study quantifies how membrane thickness, microporous layers, and operating conditions dictate internal water transport.
Catherine M. Weiss, Shiyi Wang, Brian P. Setzler, Yushan Yan, Adam Z. Weber   +4 more
wiley   +1 more source

Shear relaxation governs fusion dynamics of biomolecular condensates

Nature Communications, 2021
Phase-separated biomolecular condensates are implicated in a myriad of biological processes. Here the authors apply optical tweezers to characterize the viscoelasticity and interfacial tension of a range of condensates, finding that condensates can ...
Archishman Ghosh, Divya Kota, Huan-Xiang Zhou   +2 more
doaj   +1 more source

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source