Dietary sphinganine is selectively assimilated by members of the mammalian gut microbiome
Journal of Lipid Research, 2021 Functions of the gut microbiome have a growing number of implications for host metabolic health, with diet being one of the most significant influences on microbiome composition.
Min-Ting Lee +2 more
doaj +1 more source
The O-carbamoyl-transferase albis is responsible for the modification of albicidin [PDF]
, 2016 Albicidin is a potent antibiotic and phytotoxin produced by the sugarcane pathogenic bacterium Xanthomonas albilineans which targets the plant and bacterial DNA gyrase.[1] The infection occurs through the xylem vessels of the plants where the pathogen ...
Arasté, Julie +10 more
core +1 more source
Deep Learning‐Assisted Coherent Raman Scattering Microscopy
Advanced Intelligent Discovery, EarlyView.The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu +4 more
wiley +1 more source
Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates
AggregateThe resulting product of biocoupling is a bioconjugate, typically formed by linking molecules to proteins, oligosaccharides, nucleic acids, or synthetic polymers.
Xinzhe Yang +3 more
doaj +1 more source
Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications
Frontiers in Chemistry, 2015 Bioorthogonal chemistry has recently emerged to be one of the most powerful tools in drug discovery and chemical biology. The exploration of it has successfully advanced the field of natural product research.
Xuejun eZhu, Wenjun eZhang
doaj +1 more source
Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry. [PDF]
PLoS ONE, 2017 Prostate specific membrane antigen (PSMA) targeted microbubbles (MBs) were developed using bioorthogonal chemistry. Streptavidin-labeled MBs were treated with a biotinylated tetrazine (MBTz) and targeted to PSMA expressing cells using trans-cyclooctene ...
Aimen Zlitni +9 more
doaj +1 more source
Advances in chemical protein modification. [PDF]
, 2015 Chemical protein modification has emerged as an invaluable tool for the development of modified proteins. The complementary use of both genetic and chemical methods has provided a large toolbox that allows the preparation of almost unlimited protein ...
Bernardes, Gonçalo JL, Boutureira, Omar
core +2 more sources
Angewandte Chemie, EarlyView.Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe +7 more
wiley +1 more source
Fluorogenic and Bioorthogonal Modification of RNA Using Photoclick Chemistry
Biomolecules, 2020 A bromoaryltetrazole-modified uridine was synthesized as a new RNA building block for bioorthogonal, light-activated and postsynthetic modification with commercially available fluorescent dyes.
Katja Krell, Hans-Achim Wagenknecht
doaj +1 more source
Visualizing in situ translational activity for identifying and sorting slow-growing archaeal−bacterial consortia [PDF]
, 2016 To understand the biogeochemical roles of microorganisms in the environment, it is important to determine when and under which conditions they are metabolically active.
Connon, Stephanie A. +5 more
core +2 more sources