Results 141 to 150 of about 5,912 (181)

Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for <i>N</i>-Acetylglucosaminyltransferase I. [PDF]

J Am Chem Soc
Liu Y, Pieters S, Bineva-Todd G, Sagiroglugil M, Burnap SA, Hoddle F, Cioce A, Ohara A, Schmidt SD, Bruemmer K, Bertozzi CR, Polizzi K, Struwe WB, Rovira C, Schumann B.   +14 more
europepmc   +1 more source

Non-specific cysteine modifications on proteins induced by <i>trans</i>-cyclooctene. [PDF]

RSC Chem Biol
Yan Z, Qin W.
europepmc   +1 more source

Machine Learning-Optimized Single-Atom Catalysts Enable Microenvironment-Adaptive Chemodynamic-Bioorthogonal Cancer Therapy. [PDF]

Adv Mater
Chao X, Zhao Z, Du C, Zhou X, Wu C, Feng W, Xia L, Chen Y.   +7 more
europepmc   +1 more source

Photo-Triggered, Fast, and Fluorogenic Thiophene-Based Cycloalkynes for the Bioorthogonal Fluorescent Labeling of 1,3-Dipole-Tagged Molecules in No-Wash Conditions. [PDF]

Angew Chem Int Ed Engl
Schulz J, Chinoy ZS, Khalaf T, Li Y, Ma P, Svatunek D, Houk KN, Friscourt F.   +7 more
europepmc   +1 more source

Tunable Cell Surface Proximity Labeling via Photocatalytic and Enzymatic Activation of Fast Bioorthogonal Chemistry. [PDF]

J Am Chem Soc
Scinto SL, Makara CA, Nguyen MS, Ramaraj PK, Xie Y, Thorpe C, West GM, Am Ende CW, Xu Y, Fox JM.   +9 more
europepmc   +1 more source

Bioorthogonal Reactions of Triarylphosphines and Related Analogues

Chemical Reviews, 2021
Bioorthogonal phosphines were introduced in the context of the Staudinger ligation over 20 years ago. Since that time, phosphine probes have been used in myriad applications to tag azide-functionalized biomolecules. The Staudinger ligation also paved the way for the development of other phosphorus-based chemistries, many of which are widely employed in
Robert S Dorn, Jennifer A Prescher
exaly   +5 more sources

Nanostructured Heterogeneous Catalysts for Bioorthogonal Reactions

Angewandte Chemie - International Edition, 2023
AbstractBioorthogonal chemistry has inspired a new subarea of chemistry providing a powerful tool to perform novel biocompatible chemospecific reactions in living systems. Following the premise that they do not interfere with biological functions, bioorthogonal reactions are increasingly applied in biomedical research, particularly with respect to ...
Ana Sousa-Castillo, Begoña Puértolas Lacambra, Miguel A Correa-Duarte   +2 more
exaly   +4 more sources

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Dissociative Bioorthogonal Reactions

ChemBioChem, 2019
AbstractBioorthogonal reactions that proceed readily under physiological conditions without interference from biomolecules have found widespread application in the life sciences. Complementary to the bioorthogonal reactions that ligate two molecules, reactions that release a molecule or cleave a linker are increasingly attracting interest.
Raphael M Franzini, Julian Tu, Minghao Xu   +2 more
exaly   +3 more sources

Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions

Chemical Reviews, 2021
Bioorthogonal chemical reactions have emerged as convenient and rapid methods for incorporating unnatural functionality into living systems. Different prototype reactions have been optimized for use in biological settings. Optimization of 3 + 2 dipolar cycloadditions involving nitrones has resulted in highly efficient reaction conditions for ...
John Paul Pezacki, Didier A Bilodeau
exaly   +3 more sources