Ultrasound-Mediated OFF-to-ON Switching of Bone Regeneration via a Bioorthogonal Cell-Capture Hydrogel, Enabling Spatiotemporal Control and Monitoring. [PDF]
Xu R +10 more
europepmc +1 more source
A Chemical Framework for Engineering Extracellular Vesicles' Biointerface to Advance Precision Therapeutics. [PDF]
Pourtalebi Jahromi L +3 more
europepmc +1 more source
Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates. [PDF]
Cho YT +5 more
europepmc +1 more source
Spatiotemporal control of protein degradation: Advances in stimuli-responsive nano-PROTACs for precision cancer therapy. [PDF]
Wang A +4 more
europepmc +1 more source
Non-specific cysteine modifications on proteins induced by <i>trans</i>-cyclooctene. [PDF]
Yan Z, Qin W.
europepmc +1 more source
Spontaneous Non-Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications. [PDF]
Cai Y, Zhao C.
europepmc +1 more source
Bioorthogonal Gold-Catalyzed Hydrothiolation Leading to Amide Bond Cleavage of Ethynylated Biarylbutanamide Precursors. [PDF]
Huang J, Li Y, Du J, Liu Y, Vong K.
europepmc +1 more source
Nanostructured Heterogeneous Catalysts for Bioorthogonal Reactions [PDF]
AbstractBioorthogonal chemistry has inspired a new subarea of chemistry providing a powerful tool to perform novel biocompatible chemospecific reactions in living systems. Following the premise that they do not interfere with biological functions, bioorthogonal reactions are increasingly applied in biomedical research, particularly with respect to ...
Ana Sousa-Castillo +2 more
exaly +5 more sources
In Vivo Applications of Bioorthogonal Reactions: Chemistry and Targeting Mechanisms [PDF]
Bioorthogonal chemistry involves selective biocompatible reactions between functional groups that are not normally present in biology. It has been used to probe biomolecules in living systems, and has advanced biomedical strategies such as diagnostics ...
Helen Osborn
exaly +2 more sources
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Dissociative Bioorthogonal Reactions
ChemBioChem, 2019AbstractBioorthogonal reactions that proceed readily under physiological conditions without interference from biomolecules have found widespread application in the life sciences. Complementary to the bioorthogonal reactions that ligate two molecules, reactions that release a molecule or cleave a linker are increasingly attracting interest.
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