Results 1 to 10 of about 389 (99)

BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities. [PDF]

Int J Mol Sci, 2019
The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified.
Minkiewicz P, Iwaniak A, Darewicz M.
europepmc   +4 more sources

BIOPEP-UWM Virtual—A Novel Database of Food-Derived Peptides with In Silico-Predicted Biological Activity

Applied Sciences, 2022
The novel BIOPEP-UWM Virtual database is designed as a repository of peptide sequences whose bioactivity or taste information was the result of in silico predictions.
Piotr Minkiewicz, Anna Iwaniak, Małgorzata Darewicz   +2 more
doaj   +3 more sources

Hybrid Approach in the Analysis of Bovine Milk Protein Hydrolysates as a Source of Peptides Containing Di- and Tripeptide Bitterness Indicators

Polish Journal of Food and Nutrition Sciences, 2020
The aim of this study was to employ a hybrid approach combined with a fragmentomic idea of research used to analyze bovine milk protein hydrolysates as a source of peptides with a potential bitter taste.
Anna Iwaniak, Piotr Minkiewicz, Monika Hrynkiewicz, Justyna Bucholska, Małgorzata Darewicz   +4 more
doaj   +3 more sources

Plant-Derived Proteins and Peptides as Potential Immunomodulators [PDF]

Molecules, 2023
The immune response of humans may be modulated by certain biopeptides. The present study aimed to determine the immunomodulatory potential of plant-derived food proteins and hydrolysates obtained from these proteins via monocatalytic in silico hydrolysis
Iwona Szerszunowicz, Szymon Kozicki
doaj   +2 more sources

Prediction of the Potential of Food Proteins as Sources of Biopeptides Using BIOPEP-UWM Database

Proceedings
Peptides derived from food proteins exhibit a variety of bioactivities, such as the inhibition of angiotensin converting enzyme (ACE; EC 3.4.15.1), dipeptidyl peptidase IV (DPP4; EC 3.4.14.5), α-glucosidase (EC 3.2.1.20), α-amylase (EC 3.2.1.1), etc., as
Anna Iwaniak, Małgorzata Darewicz, Piotr Minkiewicz   +2 more
doaj   +2 more sources

Influence of the Casein Genotype on Goat Milk Bioactivity: An In Silico Analysis of the Casein Peptidome [PDF]

Molecules
Goat caseins are highly polymorphic proteins that affect milk functional properties. In this study, an in silico approach was employed to analyze the influence of goat casein allelic variants on the quantity and bioactivity potential of peptides released
Aram Y. Rubio-Reyes, Iván Delgado-Enciso, Eduardo Casas, Estela Garza-Brenner, Ana M. Sifuentes-Rincón   +4 more
doaj   +2 more sources

Unraveling bitter peptides in wheat protein hydrolysates [PDF]

Food Chemistry: Molecular Sciences
Wheat protein hydrolysates (WPHs) hold promise for functional food applications, but papain (EC 3.4.22.2)-mediated hydrolysis often results in undesirable bitterness and low yields of small peptides.
Wenmeng He, Shiqin Wang, Beibei Wang, Mingming Wang, Pan Liao   +4 more
doaj   +2 more sources

Mining anticoagulant peptides from Poecilobdella manillensis by peptidomics analysis [PDF]

Natural Products and Bioprospecting
Thrombosis triggers various severe diseases, while antithrombotic drugs carry bleeding risks, making the development of novel natural anticoagulants a subject of widespread attention.
Han-xue Zheng, Xiao-li Deng, Teng-teng Li, Guo-hua Xia, Huan Yang, Jiang-song Peng, Yu-ping Shen   +6 more
doaj   +2 more sources

Analysis of Structure–Activity Relationships of Food-Derived DPP IV-Inhibitory Di- and Tripeptides Using Interpretable Descriptors

Applied Sciences, 2023
This study aimed to analyze the structural requirements for di- and tripeptides exhibiting a DPP IV-inhibitory effect. The sequences of 46 di- and 33 tripeptides, including their bioactivity (IC50; μM), were implemented from the BIOPEP-UWM database ...
Monika Hrynkiewicz, Anna Iwaniak, Piotr Minkiewicz, Małgorzata Darewicz, Wojciech Płonka   +4 more
doaj   +1 more source

Evaluation of Protein Profiles, Bioactivity, Allergenicity and Toxicity of Peptides Generated After in silico Digestion of Common Wheat and Einkorn Wheat

Turkish Journal of Agriculture: Food Science and Technology, 2023
The belief that ancient wheat is more beneficial than common wheat has been growing trend in recent years among the consumers. The present study aims to compare bioactive peptide, allergen peptide and toxic peptide generation after gastrointestinal ...
Pelin Sultan Perçin, Sibel Karakaya
doaj   +1 more source