Results 31 to 40 of about 389 (99)

Structure–Activity Prediction of ACE Inhibitory/Bitter Dipeptides—A Chemometric Approach Based on Stepwise Regression

Molecules, 2019
Forward and backward stepwise regression (FR and BR, respectively) was applied for the structure–bioactivity prediction of angiotensin converting enzyme (ACE)-inhibitory/bitter-tasting dipeptides.
Monika Hrynkiewicz, Anna Iwaniak, Justyna Bucholska, Piotr Minkiewicz, Małgorzata Darewicz   +4 more
doaj   +1 more source

Alternative Proteins as a Source of Bioactive Peptides: The Edible Snail and Generation of Hydrolysates Containing Peptides with Bioactive Potential for Use as Functional Foods

Foods, 2021
Members of the Phylum Mollusca include shellfish such as oysters and squid but also the edible garden snail known as Helix aspersa. This snail species is consumed as a delicacy in countries including France (where they are known as petit-gris), southern ...
Maria Hayes, Leticia Mora
doaj   +1 more source

Antioxidant Properties and Prediction of Bioactive Peptides Produced from Flixweed (sophia, Descurainis sophia L.) and Camelina (Camelina sativa (L.) Crantz) Seed Meal: Integrated In Vitro and In Silico Studies

Plants, 2023
Flixweed (sophia) seed meal and camelina, both by-products of oil processing, were employed to generate protein hydrolysates by applying Flavourzyme and Alcalase. This study aimed to integrate in vitro and in silico methods to analyze sophia and camelina
Na Thi Ty Ngo, Tharindu R. L. Senadheera, Fereidoon Shahidi   +2 more
doaj   +1 more source

Antioxidant Profiling of Botryocladia leptopoda Based on In Silico and In Vitro Studies

Squalen
Seaweed has long been recognized as an excellent source of antioxidants. The presence of antioxidant activity from Botryocladia leptopoda was investigated. The study aims to estimate the potential antioxidative peptides released by B. leptopoda sequences
Fenny Crista Anastasia Panjaitan, Huey-Jine Chai   +1 more
doaj   +1 more source

Isolation, Identification and Characterization of Two Novel Peptide Inhibitors of Dipeptidyl Peptidase 4 From Mung Bean (Vigna radiata) Protein Hydrolysate: Gastric Stability and Mechanistic Insight

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
The growing global burden of diabetes warrants search for natural, food‐derived bioactive molecules, including peptides. In this paper, dipeptidyl peptidase 4 (DPP4), a type 2 diabetes drug target,inhibitory peptides from the seed protein hydrolysates of mung bean (Vigna radiata) were studied.
Gaurav Srivastava, Dharmendra K. Maurya, Sahayog N. Jamdar, Akhilesh K. Verma   +3 more
wiley   +1 more source

Debittering and Masking Soy Peptides for Oral Consumption and Immune‐Boosting Function

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Soy peptides (SPs) have been extensively studied with an emphasis on their immune‐boosting effects and production‐associated bitterness. This associated bitterness affects SPs’ oral consumption despite their bioactivities. In this review, the immune‐boosting functions, factors affecting bitterness, and consumers’ perceptions of SPs are explored ...
Wei Li, Chaoling Wen, Opeyemi Joshua Olatunji, Chi Ching Lee, Tolulope Joshua Ashaolu, Anupama Bose   +5 more
wiley   +1 more source

Anti‐Thrombotic Effect of Hemp Seed Peptides in Zebrafish by Dual Regulation of vegfr1 Signaling and Caspase‐3‐Mediated Apoptosis

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Characterize the thrombin‐inhibitory capacity of hemp seed peptides. Evaluate antithrombotic efficacy through hemodynamic and vascular parameters. Elucidate mechanisms via vegfr1 and caspase‐3 gene expression analysis. ABSTRACT This study aimed to investigate the antithrombotic activity of hemp seed peptides derived from trypsin hydrolysates and ...
Jie Shi, Jingyi Ge, Zhenghai Zhang, Lianhui Wei, Yan Dong, Guowei Li, Qingli Yang, Jing Pan, Yanru Ji   +8 more
wiley   +1 more source

GRU4ACE: Enhancing ACE inhibitory peptide prediction by integrating gated recurrent unit with multi‐source feature embeddings

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Accurate identification of angiotensin‐I‐converting enzyme (ACE) inhibitory peptides is essential for understanding the primary factor regulating the renin‐angiotensin system and guiding the development of new drug candidates. Given the inherent challenges in experimental processes, computational methods for in silico peptide identification ...
Saeed Ahmed, Nalini Schaduangrat, Pramote Chumnanpuen, Watshara Shoombuatong   +3 more
wiley   +1 more source

Revitalising Brewers' Spent Grains and Enriching With Biogenic Compounds Through the Fermentation of Fructophilic Lactic Acid Bacteria and Yeasts

Microbial Biotechnology, Volume 18, Issue 6, June 2025.
Non‐conventional starters (F. fructosus PL22 and W. anomalus GY1) enrich brewer's spent grain (BSG) portfolio of bioactive compounds. Fermented BSG showed antioxidant and antifungal activities and boosted keratinocyte proliferation, FLG expression, and wound healing.
Alessandro Stringari, Ali Zein Alabiden Tlais, Stefano Tonini, Daniela Pinto, Giorgia Mondadori, Pasquale Filannino, Raffaella Di Cagno, Marco Gobbetti   +7 more
wiley   +1 more source

In Silico Evaluation of Human α‐S1‐Casein, β‐Casein, and κ‐Casein as a Source of Bioactive Peptides

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Human caseins (α‐S1, β, and κ‐casein) represent a potential source of bioactive peptides with possible therapeutic applications, particularly for neonates. Due to the relevance of obtaining bioactive peptides, an in silico simulation of enzymatic hydrolysis with pepsin (pH > 2) was performed on these proteins using the PeptideCutter tool from Expasy ...
Diego Arturo Zavala Trejo, Blanca Rosa Aguilar Uscanga, Ariana Rodríguez Arreola, Esperanza González Quezada, Josué Raymundo Solís Pacheco, Anupama Bose   +5 more
wiley   +1 more source