Edible Yellow Mealworm-Derived Antidiabetic Peptides: Dual Modulation of α-Glucosidase and Dipeptidyl-Peptidase IV Inhibition Revealed by Integrated Proteomics, Bioassays, and Molecular Docking Analysis [PDF]
FoodsType 2 diabetes mellitus (T2DM) poses a critical global health burden, necessitating safer multi-target therapies. We pioneer the exploration of novel bioactive peptides from Tenebrio molitor larvae—an underexplored, sustainable, and edible insect ...
Yuying Zhu +4 more
doaj +2 more sources
The use of a biopeptide with antiviral properties as a functional ingredient for ice cream [PDF]
BIO Web of ConferencesBiopeptides are used in food products to give them a functional orientation. The purpose of the study is to characterize and use a biopeptide with antiviral properties for the production of ice cream with functional purpose.
Merzlyakova N.V. +2 more
doaj +2 more sources
Prediction of the Potential of Food Proteins as Sources of Biopeptides Using BIOPEP-UWM Database [PDF]
ProceedingsPeptides derived from food proteins exhibit a variety of bioactivities, such as the inhibition of angiotensin converting enzyme (ACE; EC 3.4.15.1), dipeptidyl peptidase IV (DPP4; EC 3.4.14.5), α-glucosidase (EC 3.2.1.20), α-amylase (EC 3.2.1.1), etc., as
Anna Iwaniak +2 more
doaj +2 more sources
Honey-Conjugated Honeybee Brood Biopeptides Improve Gastrointestinal Stability, Antioxidant Capacity, and Alleviate Diet-Induced Metabolic Syndrome in a Rat Model. [PDF]
FoodsOunjaijean S +7 more
europepmc +3 more sources
Characterization and Identification of Cryptic Biopeptides inCarya illinoinensis(Wangenh K. Koch) Storage Proteins [PDF]
BioMed Research International, 2017 The objective of this research was to identify and characterize the encoded peptides present in nut storage proteins ofCarya illinoinensis. It was found, through in silico prediction, proteomic analysis, and MS spectrometry, that bioactive peptides were mainly found in albumin and glutelin fractions. Glutelin was the major fraction with ~53% of the nut
Everardo Mares‐Mares +5 more
openalex +3 more sources
A novel approach to assessing the bioavailability of biopeptide inhibitor of HMG CoA reductase from germinated and ungerminated Kara Kratok (<i>Phaseolus lunatus</i> L.). [PDF]
PeerJBudiyanto C +3 more
europepmc +3 more sources
Marine sourced tripeptide SRP and its sustained-release formulation SRP-PLGA-MS exhibiting antihypertensive effect in spontaneously hypertensive rats and HUVECs [PDF]
Frontiers in NutritionBiopeptides from Sipunculus nudus were reported with good ACE inhibitory activity, and the tripeptide SRP was one with the highest ACE inhibition rate. However, the disadvantage of short half-life limited the development of peptide drugs.
Miaoen Huang +17 more
doaj +2 more sources
Discovery of a novel tetrapeptide as glucose homeostasis modulator with bifunctionalities of targeting DPP-IV and microbiota. [PDF]
ImetaAI‐driven and computation‐based high‐throughput methods were developed to mine novel dipeptidyl peptidase IV (DPP‐IV) inhibitory peptides from hemp seed proteins. The identified peptide VAMP demonstrates a glucose‐lowering effect through dual mechanisms: inhibition of DPP‐IV activity and selective promotion of intestinal Akkermansia muciniphila growth.
Chen H +10 more
europepmc +2 more sources
Clinical Evaluation of an Integrated Tri-Modal Transdermal Device for Enhanced Serum Absorption. [PDF]
J Cosmet DermatolJournal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
Kim Y +7 more
europepmc +2 more sources
Biopeptides and immune exclusion [PDF]
Canadian Medical Association Journal, 2006 Successful probiotics have the ability to adhere to the gut preventing attachment of pathogenic bacteria and help to restore immunologic quiescence. Unfortunately, Nandini Dendukuri and colleagues' systematic review[1][1] was unable to find clinical benefit for treatment of Clostridium difficile –
Sujoy Khan
openalex +3 more sources