Unlocking Antimicrobial Peptides: In Silico Proteolysis and Artificial Intelligence-Driven Discovery from Cnidarian Omics [PDF]
MoleculesOvercoming the growing challenge of antimicrobial resistance (AMR), which affects millions of people worldwide, has driven attention for the exploration of marine-derived antimicrobial peptides (AMPs) for innovative solutions. Cnidarians, such as corals,
Agostinho Antunes +2 more
exaly +8 more sources
Discovery of Anti-Hypertensive Oligopeptides from Adlay Based on In Silico Proteolysis and Virtual Screening [PDF]
International Journal of Molecular Sciences, 2016 Adlay (Coix larchryma-jobi L.) was the commonly used Traditional Chinese Medicine (TCM) with high content of seed storage protein. The hydrolyzed bioactive oligopeptides of adlay have been proven to be anti-hypertensive effective components. However, the
Liansheng Qiao +2 more
exaly +7 more sources
Novel dipeptidyl peptidase‐IV and angiotensin‐I‐converting enzyme inhibitory peptides released from quinoa protein by in silico proteolysis [PDF]
Food Science and Nutrition, 2020 Quinoa protein has been paid more and more attention because of its nutritional properties and beneficial effects. With the development of bioinformatics, bioactive peptide database and computer‐assisted simulation provide an efficient and time‐saving ...
Nadia Everaert +2 more
exaly +6 more sources
In silico proteolysis and analysis of bioactive peptides from sequences of fatty acid desaturase 3 (FAD3) of flaxseed protein. [PDF]
Saudi J Biol Sci, 2021 Flaxseed (Linum usitatissimum), commonly known as linseed is an oilseed crop, emerging as an important and functional ingredient of food and has been paid more attention due to its nutritional value as well as beneficial effects.
Langyan S +7 more
europepmc +4 more sources
Potential Biological Activities of Peptides Generated during Casein Proteolysis by Curly Kale (Brassica oleracea L. var. sabellica L.) Leaf Extract: An In Silico Preliminary Study [PDF]
Foods, 2021 This study is a brief report on the proteolytic activity of curly kale leaf extract against casein. Casein degradation products and an in silico analysis of the biological activity of the peptides obtained was performed.
Magdalena Polak-Berecka +5 more
doaj +4 more sources
Catalysts, 2023 Despite their potential as a protein source for human consumption, the health benefits of black soldier fly larvae (BSFL) proteins following human gastrointestinal (GI) digestion are poorly understood.
Mohamad Zulkeflee Sabri +2 more
exaly +6 more sources
IP Indian Journal of Clinical and Experimental DermatologySkin diseases represent a significant burden on global healthcare systems, with protein deposition playing a pivotal role in their pathogenesis, including conditions such as macular amyloidosis.
Vrushali Neve +4 more
exaly +3 more sources
Identification of Novel Umami Peptides from Yak Bone Collagen and Mechanism Exploration Through In Silico Discovery, Molecular Docking, and Electronic Tongue [PDF]
FoodsUmami peptides were screened and identified from yak bone collagen for the first time by in silico analysis, molecular docking, and electronic tongue.
Yimeng Mei +9 more
doaj +3 more sources
Characteristics of Biopeptides Released In Silico from Collagens Using Quantitative Parameters
Foods, 2020 The potential of collagens to release biopeptides was evaluated using the BIOPEP-UWM-implemented quantitative criteria including the frequency of the release of fragments with a given activity by selected enzyme(s) (AE), relative frequency of release of ...
Anna Iwaniak +2 more
exaly +3 more sources
A Model of Demasking and Hydrolysis of Peptide Bonds During Tryptic Digestion of β-Casein and β-Lactoglobulin [PDF]
MoleculesThe prediction of polypeptide chain fragmentation during digestion (proteolysis) of protein substrates by trypsin was carried out for globular β-lactoglobulin (β-LG) and micellar β-casein (β-CN).
Mikhail M. Vorob’ev
doaj +2 more sources