Results 21 to 30 of about 16,756 (205)

Evaluation of Antioxidant Activities from a Sustainable Source of Okara Protein Hydrolysate Using Enzymatic Reaction

Molecules, 2023
Okara is a solid byproduct created during the processing of soy milk. The production of protein hydrolysates utilizing enzymatic tests such as papain can result in the production of bioactive peptides (BPs), which are amino acid sequences that can also ...
Andriati Ningrum, Dian Wahyu Wardani, Nurul Vanidia, Manikharda, Achmat Sarifudin, Rima Kumalasari, Riyanti Ekafitri, Dita Kristanti, Woro Setiaboma, Heli Siti Helimatul Munawaroh   +9 more
doaj   +1 more source

Function of SYDE C2-RhoGAP family as signaling hubs for neuronal development deduced by computational analysis

Scientific Reports, 2022
Recent investigations of neurological developmental disorders have revealed the Rho-family modulators such as Syde and its interactors as the candidate genes.
Zen Kouchi, Masaki Kojima
doaj   +1 more source

Soybean (Glycine max) Protein Hydrolysates as Sources of Peptide Bitter-Tasting Indicators: An Analysis Based on Hybrid and Fragmentomic Approaches

Applied Sciences, 2020
The aim of this study was to analyze soybean proteins as sources of peptides likely to be bitter using fragmentomic and hybrid approaches involving in silico and in vitro studies.
Anna Iwaniak, Monika Hrynkiewicz, Piotr Minkiewicz, Justyna Bucholska, Małgorzata Darewicz   +4 more
doaj   +1 more source

Online tools to support teaching and training activities in chemical engineering: enzymatic proteolysis

Frontiers in Education, 2023
The practical teaching or training of enzymatic proteolysis can prove challenging because of the lengthy duration of the process, the complexity of identifying short amino acid sequences, the high cost of the enzymes, and the need to use very specific ...
Silvia Villaró-Cos, Silvia Villaró-Cos, Tomas Lafarga, Tomas Lafarga   +3 more
doaj   +1 more source

Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development

Scientific Reports, 2021
Fungal infection is an important health problem in Latin America, and in Brazil in particular. Paracoccidioides (mainly P. brasiliensis and P. lutzii) is responsible for paracoccidioidomycosis, a disease that affects mainly the lungs.
Thyago R. Cardim-Pires, Ricardo Sant’Anna, Debora Foguel   +2 more
doaj   +1 more source

Antioxidant Properties and Prediction of Bioactive Peptides Produced from Flixweed (sophia, Descurainis sophia L.) and Camelina (Camelina sativa (L.) Crantz) Seed Meal: Integrated In Vitro and In Silico Studies

Plants, 2023
Flixweed (sophia) seed meal and camelina, both by-products of oil processing, were employed to generate protein hydrolysates by applying Flavourzyme and Alcalase. This study aimed to integrate in vitro and in silico methods to analyze sophia and camelina
Na Thi Ty Ngo, Tharindu R. L. Senadheera, Fereidoon Shahidi   +2 more
doaj   +1 more source

Antigen processing and presentation in cancer immunotherapy

Journal for ImmunoTherapy of Cancer, 2020
Background Knowledge about and identification of T cell tumor antigens may inform the development of T cell receptor-engineered adoptive cell transfer or personalized cancer vaccine immunotherapy.
Maxwell Y Lee, Cem Sievers, Clint T Allen, Jun W Jeon   +3 more
doaj   +1 more source

Specific inhibitors of urokinase plasminogen activator for treatment of cancers; In silico approach

Translation, 2020
Invasion, metastasis and angiogenesis are fundamental processes in the development of solid cancers. All these depend on the proteolysis where plasminogen activation system (PAS) is the prominent component.
Benjamin Talbot, Jerzy Jankun
doaj   +1 more source

Identification of Antibacterial Peptide Candidates Encrypted in Stress-Related and Metabolic Saccharomyces cerevisiae Proteins

Pharmaceuticals, 2022
The protein-rich nature of Saccharomyces cerevisiae has led this yeast to the spotlight concerning the search for antimicrobial peptides. Herein, a
Maria Fernanda da Silva Santos, Cyntia Silva Freitas, Giovani Carlo Verissimo da Costa, Patricia Ribeiro Pereira, Vania Margaret Flosi Paschoalin   +4 more
doaj   +1 more source

New compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Aβ aggregation, AChE, and BACE1 in the Alzheimer disease

PLoS ONE, 2022
The preset neurodegenerations in Alzheimer disease (AD) are due to several mechanisms such as amyloidogenic proteolysis, neuroinflammation, mitochondrial dysfunction, neurofibrillary tangles, cholinergic dysfunction, among others.
Iohanan Daniel García Marín, Raúl Horacio Camarillo López, Oscar Aurelio Martínez, Itzia Irene Padilla-Martínez, José Correa-Basurto, Martha Cecilia Rosales-Hernández   +5 more
doaj   +2 more sources