Results 21 to 30 of about 117,925,879 (224)

In-silico structural and functional characterization of a V. cholerae O395 hypothetical protein containing a PDZ1 and an uncommon protease domain. [PDF]

PLoS ONE, 2013
Vibrio cholerae, the causative agent of epidemic cholera, has been a constant source of concern for decades. It has constantly evolved itself in order to survive the changing environment.
Avirup Dutta, Atul Katarkar, Keya Chaudhuri   +2 more
doaj   +1 more source

The use of UniProtKB/BIOPEP for the analysis of oat globulin physicochemical parameters and bioactivity

Czech Journal of Food Sciences, 2018
The physico-chemical properties of oat proteins (globulins) were determined and an analysis was done whether products of in silico proteolysis contain mono- and multi-functional peptides with various biological activity.
Iwona SZERSZUNOWICZ, Dorota NAŁĘCZ
doaj   +1 more source

Evaluation of Antioxidant Activities from a Sustainable Source of Okara Protein Hydrolysate Using Enzymatic Reaction

Molecules, 2023
Okara is a solid byproduct created during the processing of soy milk. The production of protein hydrolysates utilizing enzymatic tests such as papain can result in the production of bioactive peptides (BPs), which are amino acid sequences that can also ...
Andriati Ningrum, Dian Wahyu Wardani, Nurul Vanidia, Manikharda, Achmat Sarifudin, Rima Kumalasari, Riyanti Ekafitri, Dita Kristanti, Woro Setiaboma, Heli Siti Helimatul Munawaroh   +9 more
doaj   +1 more source

The acceptance of in silico models for REACH: Requirements, barriers, and perspectives [PDF]

, 2011
In silico models have prompted considerable interest and debate because of their potential value in predicting the properties of chemical substances for regulatory purposes.
Antonio Cassano, R. Gonella Diaza, Giuseppina Gini, Simon Pardoe, Rodolfo Gonella Diaza, Rodolfo Diaza, Knauf Ralf, Pardoe, Simon, Benighaus, Ludger, L. Benighaus, Cassano Antonio, A. Cassano, E. Benfenati, Mays, Claire, S. Pardoe, C. Mays, Ludger Benighaus, R. Knauf, Ralf Knauf, Benighaus Ludger, Gini Giuseppina, Emilio Benfenati, Knauf, Ralf, Claire Mays, Mays Claire, Benfenati Emilio, Gini, Giuseppina, Diaza Rodolfo, Gonella Diaza, Rodolfo, Cassano, Antonio, Benfenati, Emilio, Pardoe Simon   +31 more
core   +1 more source

Soybean (Glycine max) Protein Hydrolysates as Sources of Peptide Bitter-Tasting Indicators: An Analysis Based on Hybrid and Fragmentomic Approaches

Applied Sciences, 2020
The aim of this study was to analyze soybean proteins as sources of peptides likely to be bitter using fragmentomic and hybrid approaches involving in silico and in vitro studies.
Anna Iwaniak, Monika Hrynkiewicz, Piotr Minkiewicz, Justyna Bucholska, Małgorzata Darewicz   +4 more
doaj   +1 more source

Function of SYDE C2-RhoGAP family as signaling hubs for neuronal development deduced by computational analysis

Scientific Reports, 2022
Recent investigations of neurological developmental disorders have revealed the Rho-family modulators such as Syde and its interactors as the candidate genes.
Zen Kouchi, Masaki Kojima
doaj   +1 more source

Online tools to support teaching and training activities in chemical engineering: enzymatic proteolysis

Frontiers in Education, 2023
The practical teaching or training of enzymatic proteolysis can prove challenging because of the lengthy duration of the process, the complexity of identifying short amino acid sequences, the high cost of the enzymes, and the need to use very specific ...
Silvia Villaró-Cos, Silvia Villaró-Cos, Tomas Lafarga, Tomas Lafarga   +3 more
doaj   +1 more source

Antigen processing and presentation in cancer immunotherapy

Journal for ImmunoTherapy of Cancer, 2020
Background Knowledge about and identification of T cell tumor antigens may inform the development of T cell receptor-engineered adoptive cell transfer or personalized cancer vaccine immunotherapy.
Maxwell Y Lee, Cem Sievers, Clint T Allen, Jun W Jeon   +3 more
doaj   +1 more source

Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development

Scientific Reports, 2021
Fungal infection is an important health problem in Latin America, and in Brazil in particular. Paracoccidioides (mainly P. brasiliensis and P. lutzii) is responsible for paracoccidioidomycosis, a disease that affects mainly the lungs.
Thyago R. Cardim-Pires, Ricardo Sant’Anna, Debora Foguel   +2 more
doaj   +1 more source

Specific inhibitors of urokinase plasminogen activator for treatment of cancers; In silico approach

Translation, 2020
Invasion, metastasis and angiogenesis are fundamental processes in the development of solid cancers. All these depend on the proteolysis where plasminogen activation system (PAS) is the prominent component.
Benjamin Talbot, Jerzy Jankun
doaj   +1 more source