Potential Biological Activities of Peptides Generated during Casein Proteolysis by Curly Kale (Brassica oleracea L. var. sabellica L.) Leaf Extract: An In Silico Preliminary Study [PDF]
Foods, 2021 This study is a brief report on the proteolytic activity of curly kale leaf extract against casein. Casein degradation products and an in silico analysis of the biological activity of the peptides obtained was performed.
Magdalena Polak-Berecka +5 more
doaj +3 more sources
In silico proteolysis and analysis of bioactive peptides from sequences of fatty acid desaturase 3 (FAD3) of flaxseed protein. [PDF]
Saudi J Biol Sci, 2021 Flaxseed (Linum usitatissimum), commonly known as linseed is an oilseed crop, emerging as an important and functional ingredient of food and has been paid more attention due to its nutritional value as well as beneficial effects. It is mainly rich in is α-linolenic acid (ALA, omega-3 fatty acid), fibres and lignans that have potential health benefits ...
Langyan S +7 more
europepmc +3 more sources
Zinc metalloproteinases and amyloid Beta-Peptide metabolism : the positive side of proteolysis in Alzheimer's disease [PDF]
, 2011 Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (Aβ-)peptides in the brain causing progressive neuronal death.
Gough, Mallory +2 more
core +5 more sources
Catalysts, 2023 Despite their potential as a protein source for human consumption, the health benefits of black soldier fly larvae (BSFL) proteins following human gastrointestinal (GI) digestion are poorly understood. This computational study explored the potential of BSFL proteins to release healthpromoting peptides after human GI digestion.
Chai, Tsun-Thai +4 more
openaire +4 more sources
Food Hydrocolloids for Health, 2023 The protein hydrolysate that contains bioactive peptides of yellowfin tuna (Thunnus albacares) skin collagen with antioxidant activity has been successfully studied by using in silico and in vitro assays. We found that using the in silico assessment, the
Dian Wahyu Wardani +6 more
doaj +1 more source
Characteristics of Potential Protein Nutraceuticals of Plant Origin with Antioxidant Activity
Molecules, 2020 This study used selected plant proteins and the tools available in the BIOPEP-UWM database to profile proteins and release antioxidant nutraceuticals from their primary structures. The frequency of the occurrence of fragments with antioxidant activity in
Iwona Szerszunowicz, Jan Kłobukowski
doaj +1 more source
An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII. [PDF]
PLoS ONE, 2017 Coagulation Factor VIII is activated by an ordered limited thrombin proteolysis with different catalytic efficiency at three P1 Arginine residues: Arg759> Arg1708>Arg391, indicating the flanking residues of the latter to be less optimal. This study aimed
Behnaz Pezeshkpoor +7 more
doaj +1 more source
Marine Drugs, 2022 Bioinformatic tools are widely used in predicting potent bioactive peptides from food derived materials. This study was focused on utilizing sea cucumber processing by-products for generating antioxidant and ACE inhibitory peptides by application of a ...
Tharindu R. L. Senadheera +3 more
doaj +1 more source
Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras [PDF]
, 2021 A current bottleneck in the development of proteolysis targeting chimeras (PROTACs) is the empirical nature of linker length structure-activity relationships (SARs). A multidisciplinary approach to alleviate the bottleneck is detailed here.
Bemis, Troy A +8 more
core +1 more source
Green seaweed Ulva lactuca, a potential source of bioactive peptides revealed by in silico analysis
Informatics in Medicine Unlocked, 2022 The green seaweed Ulva lactuca is found in coastal areas. Potential bioactive peptides have a wide range of uses, including antibacterial, antifungal, antiviral, alpha-amylase inhibitory, antiamnestic, ACE inhibitory, immunomodulatory, anticancer ...
Md.Ariful Amin +3 more
doaj +1 more source